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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 12
Integrative analyses that summarize and link molecular data to treatment sensitivity are crucial to capture the biological complexity which is essential to... 
Biotechnology | Integration | Factor analysis | Sensitivity analysis | Data integration | Xenotransplantation | Predictions | Xenografts | Cell lines | Cancer
Journal Article
Cell, ISSN 0092-8674, 07/2016, Volume 166, Issue 3, pp. 740 - 754
Journal Article
Metabolomics, ISSN 1573-3882, 2008, Volume 4, Issue 1, pp. 81 - 89
Journal Article
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 09/2015, Volume 7, Issue 9, pp. 1104 - 1118
Journal Article
Bioinformatics, ISSN 1367-4803, 2016, Volume 32, Issue 17, pp. i413 - i420
Motivation: Clinical response to anti-cancer drugs varies between patients. A large portion of this variation can be explained by differences in molecular... 
SIGNALING PATHWAYS | ENCYCLOPEDIA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEASOME | KNOWLEDGE | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | SENSITIVITY | INHIBITOR | HDAC6 | Cell Line | Gene Expression | Neoplasms - genetics | Humans | Gene Dosage | Gene Expression Profiling | DNA Damage | Mutation | Drug Delivery Systems | Neoplasms - drug therapy
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2018, Volume 33, Issue 6, pp. 1078 - 1093.e12
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 2007, Volume 8, Issue 1, pp. 322 - 322
Journal Article
Cell Research, ISSN 1001-0602, 07/2018, Volume 28, Issue 7, pp. 719 - 729
Activation of the mitogen-activated protein kinase (MAPK) pathway is frequent in cancer. Drug development efforts have been focused on kinases in this pathway,... 
COMPREHENSIVE MOLECULAR PORTRAITS | COLON-CANCER | SURVIVAL | DRUG-SENSITIVITY | CLINICAL-TRIAL | LOBULAR BREAST-CANCER | GROWTH | C-JUN | EXPRESSION | EGFR | CELL BIOLOGY | Tyrosine | Xenotransplantation | MEK inhibitors | MAP kinase | Raf protein | Activation | Feedback loops | Drug development | Kinases | Proteins | Sensitivity | Inhibitors | Protein kinase | Coding | Xenografts | Tumor suppressor genes | Mutation | Colon | Inhibition | Prostate | Cancer | Tumors
Journal Article
American Journal of Physiology, ISSN 0193-1849, 02/2010, Volume 298, Issue 2, p. E146
  The detection of hormone secretion episodes is important for understanding normal and abnormal endocrine functioning, but pulse identification from hormones... 
Simulation | Endocrine system | Growth hormones | Methods | Validation studies
Journal Article
Cell Reports, ISSN 2211-1247, 07/2017, Volume 20, Issue 1, pp. 48 - 60
Diffuse and uncontrollable brain invasion is a hallmark of glioblastoma (GBM), but its mechanism is understood poorly. We developed a 3D ex vivo organotypic... 
collagen | interferon regulatory factor 3 | glioblastoma | invasion | casein kinase 2 | extracellular matrix | MIGRATION | GLIOMAS | INVASION | ACTIVATION | TGF-BETA | MODELS | PROTEIN-KINASE CK2 | GROWTH | EXTRACELLULAR-MATRIX | CULTURE | CELL BIOLOGY
Journal Article
International Journal of Cancer, ISSN 0020-7136, 10/2018, Volume 143, Issue 7, pp. 1764 - 1773