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by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Index Medicus | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article
Advances in Global Change Research, ISSN 1574-0919, 2019, Volume 64, pp. 153 - 172
Journal Article
by Jayasinghe, Reyka G and Cao, Song and Gao, Qingsong and Gao, Jianjiong and Gao, Galen F and Wendl, Michael C and Vo, Nam Sy and Reynolds, Sheila and Reynolds, Sheila M and Zhao, Fengmei and Zhao, Yanyan and Climente-González, Héctor and Chai, Shengjie and Wang, Zhining and Wang, Fang and Wang, Min and Wang, Jing and Wang, Timothy and Wang, Linghua and Wang, Jioajiao and Varghese, Rajees and Huang, Mo and Liang, Wen-Wei and Liang, Han and Wyczalkowski, Matthew A and Sengupta, Sohini and Li, Zhi and Li, Wei and Li, Jun and Payne, Samuel H and Fenyö, David and Miner, Jeffrey H and Walter, Matthew J and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Liming and Yang, Ju Dong and Yang, Ian and Yang, Hannah and Zenklusen, Jean C and Zhang, Hailei and Zhang, Wei and Zhang, Jiashan (Julia) and Zhang, Lizhi and Zhang, Jiexin and Zhang, Hongxin and Zhang, Hongzheng and Chudamani, Sudha and Liu, Wenbin and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Judy and Miller, Christopher A and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 270 - 281.e3
For the past decade, cancer genomic studies have focused on mutations leading to splice-site disruption, overlooking those having splice-creating potential.... 
RNA | mutations of clinical relevance | splicing | BREAST-CANCER | INACTIVATION | RETINOBLASTOMA | REPORTER MINIGENE | MESSENGER-RNA | TRANSCRIPTOME | UNCLASSIFIED VARIANTS | GENETIC-VARIANTS | ABERRANT | SYNONYMOUS MUTATIONS | CELL BIOLOGY | BASIC BIOLOGICAL SCIENCES
Journal Article
01/2016, ISBN 1369683960
Advances in technologies currently produce more and more cost-effective, high-throughput, and large-scale biological data. As a result, there is an urgent need... 
Computer science | Statistics | Bioinformatics
Dissertation
World Academy of Science, Engineering and Technology, ISSN 2010-376X, 03/2009, Volume 39, pp. 478 - 484
Journal Article
Journal Article
Journal Article
Canadian Respiratory Journal, ISSN 1198-2241, 2018, Volume 2018, pp. 1732946 - 11
Introduction. Subjects with asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) share common features of patients with asthma and COPD. Our study... 
OBSTRUCTIVE PULMONARY-DISEASE | RESPIRATORY SYSTEM | ADULTS | SMOKING | PREVALENCE | EXHALED NITRIC-OXIDE | CARE | Medicine, Experimental | Medical research | Sleep apnea syndromes | Comparative analysis | Asthma | Dyspnea | Statistical analysis | Laboratories | Critical care | Chronic obstructive pulmonary disease | Family medical history | Medical diagnosis | Primary care | Index Medicus
Journal Article