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1. Full Text Protein kinase D inhibitor CRT0066101 suppresses bladder cancer growth in vitro and xenografts via blockade of the cell cycle at G2/M
by Li, Qingdi Quentin and Li, Qingdi Quentin and Hsu, Iawen and Hsu, Iawen and Sanford, Thomas and Sanford, Thomas and Railkar, Reema and Railkar, Reema and Balaji, Navin and Balaji, Navin and Sourbier, Carole and Sourbier, Carole and Vocke, Cathy and Vocke, Cathy and Balaji, K C and Balaji, K C and Agarwal, Piyush K and Agarwal, Piyush K
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 3/2018, Volume 75, Issue 5, pp. 939 - 963
Life Sciences | Biomedicine, general | Biochemistry, general | c-Jun phosphorylation | RNA interference | Life Sciences, general | TCGA database | Invasion and migration | Protein kinase D inhibitor | Cell Biology | G2/M cell cycle arrest | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Proteins | Prevention | RNA | Growth | Analysis | Cell cycle | Development and progression | Bladder cancer | Protein kinases | Cancer | Flow cytometry | Biotechnology | Regulators | Bladder | Kinases | Tissues | Cyclin B1 | Anticancer properties | Urinary bladder | Xenografts | Inhibition | Urothelial carcinoma | Explants | CHK1 protein | Tumor cell lines | Ribonucleic acid--RNA | Cytometry | 14-3-3 protein | Inhibitors | Protein kinase | Isoforms | Cyclin-dependent kinase inhibitor p27 | Antitumor activity | Cell migration | Index Medicus
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2. Full Text An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
by Liu, Jianfang and Lichtenberg, Tara and Hoadley, Katherine A and Poisson, Laila M and Cherniack, Andrew D and Kovatich, Albert J and Benz, Christopher C and Lee, Adrian V and Omberg, Larsson and Shriver, Craig D and Thorsson, Vesteinn and Caesar-Johnson, Samantha J and Kasapi, Melpomeni and Ferguson, Martin L and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Zenklusen, Jean C and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Noble, Michael S and Saksena, Gordon and Voet, Doug and Zhang, Hailei and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Reynolds, Sheila and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Kanchi, Rupa S and Korkut, Anil and Li, Jun and Liang, Han and Ling, Shiyun and Mills, Gordon B and Rao, Arvind and Ryan, Michael and Wang, Jing and Weinstein, John N and Zhang, Jiexin and Abeshouse, Adam and Armenia, Joshua and Chakravarty, Debyani and Chatila, Walid K and de Bruijn, Ino and Gao, Jianjiong and Gross, Benjamin E and Kundra, Ritika and Ladanyi, Marc and Luna, Augustin and Nissan, Moriah G and Ochoa, Angelica and Phillips, Sarah M and Reznik, Ed and Sander, Chris and Sheridan, Robert and Taylor, Barry S and Wang, Jioajiao and Peto, Myron and Spellman, Paul and Wilkerson, Matthew D and Brooks, Denise and Chuah, Eric and Dhalla, Noreen and Holt, Robert and Jones, Steven J.M and Lee, Darlene and Marra, Marco A and Moore, Richard A and Mungall, Andrew J and Mungall, Karen and Robertson, A. Gordon and Sadeghi, Sara and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Thiessen, Nina and Tse, Kane and Wong, Tina and Beroukhim, Rameen and Cherniack, Andrew D and Gao, Galen F and Ha, Gavin and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell (Cambridge), ISSN 0092-8674, 04/2018, Volume 173, Issue 2, pp. 400 - 416.e11
disease-specific survival | disease-free interval | overall survival | Cox proportional hazards regression model | translational research | progression-free interval | TCGA | follow-up time | The Cancer Genome Atlas | clinical data resource | Biochemistry, Genetics and Molecular Biology(all) | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - genetics | Genomics | Humans | Kaplan-Meier Estimate | Proportional Hazards Models | Databases, Genetic | Neoplasms - mortality | Neoplasms - pathology | Index Medicus
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3. Full Text Comprehensive Characterization of Cancer Driver Genes and Mutations
by Bailey, Matthew H and Porta-Pardo, Eduard and Sengupta, Sohini and Weerasinghe, Amila and Colaprico, Antonio and Wendl, Michael C and Kim, Jaegil and Reardon, Brendan and Ng, Patrick Kwok-Shing and Jeong, Kang Jin and Cao, Song and Wang, Zixing and Gao, Jianjiong and Gao, Qingsong and Liu, Eric Minwei and Mularoni, Loris and Rubio-Perez, Carlota and Nagarajan, Niranjan and Zhou, Daniel Cui and Liang, Wen-Wei and Gonzalez-Perez, Abel and Suphavilai, Chayaporn and Park, Peter J and Van Allen, Eliezer M and Liang, Han and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Hutter, Carolyn M and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zhang, Jiashan (Julia) and Chudamani, Sudha and Naresh, Rashi and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Heiman, David I and Noble, Michael S and Voet, Doug and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Leinonen, Kalle and Miller, Michael and Reynolds, Sheila and Shmulevich, Ilya and Zhang, Wei and Akbani, Rehan and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Li, Jun and Liang, Han and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and Wang, Jing and Zhang, Jiexin and Abeshouse, Adam and Armenia, Joshua and Chakravarty, Debyani and Chatila, Walid K and de Bruijn, Ino and Ladanyi, Marc and Luna, Augustin and Ochoa, Angelica and Reznik, Ed and Sanchez-Vega, Francisco and Sander, Chris and Schultz, Nikolaus and Sheridan, Robert and Sumer, S. Onur and Sun, Yichao and Taylor, Barry S and Anur, Pavana and Peto, Myron and Benz, Christopher and Stuart, Joshua M and Wong, Christopher K and Yau, Christina and Parker, Joel S and Wilkerson, Matthew D and Balasundaram, Miruna and Bowlby, Reanne and Brooks, Denise and Chuah, Eric and Dhalla, Noreen and Holt, Robert and Jones, Steven J.M and Kasaian, Katayoon and Lee, Darlene and Ma, Yussanne and Marra, Marco A and ... and The MC3 Working Group and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and MC3 Working Grp and MC3 Working Group and Cancer Genome Atlas Research Network
Cell (Cambridge), ISSN 0092-8674, 04/2018, Volume 173, Issue 2, pp. 371 - 385.e18
structure analysis | mutations of clinical relevance | oncology | driver gene discovery | Biochemistry, Genetics and Molecular Biology(all) | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus | Oncology | driver discovery
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4. Full Text Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas
by Liu, Yang and Sethi, Nilay S and Hinoue, Toshinori and Cherniack, Andrew D and Sanchez-Vega, Francisco and Kim, Jaegil and Kanchi, Rupa S and Willis, Joseph E and Wang, Kenneth K and McCall, Shannon J and Mishra, Lopa and Ojesina, Akinyemi I and Bullman, Susan and Pedamallu, Chandra Sekhar and Caesar-Johnson, Samantha J and Demchok, John A and Kasapi, Melpomeni and Ferguson, Martin L and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean C and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Wan, Yunhu and DeFreitas, Timothy and Frazer, Scott and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Noble, Michael S and Saksena, Gordon and Voet, Doug and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Liu, Yuexin and Miller, Michael and Reynolds, Sheila and Thorsson, Vesteinn and Zhang, Wei and Akbani, Rehan and Broom, Bradley M and Ju, Zhenlin and Korkut, Anil and Li, Jun and Liang, Han and Ling, Shiyun and Wang, Jing and Weinstein, John N and Abeshouse, Adam and Chakravarty, Debyani and Chatila, Walid K and Bruijn, Inode and Gross, Benjamin E and Ladanyi, Marc and Luna, Augustin and Nissan, Moriah G and Ochoa, Angelica and Sanchez-Vega, Francisco and Sander, Chris and Schultz, Nikolaus and Sheridan, Robert and Sumer, S. Onur and Sun, Yichao and Taylor, Barry S and Anur, Pavana and Peto, Myron and Spellman, Paul and Benz, Christopher and Stuart, Joshua M and Yau, Christina and Wilkerson, Matthew D and Ally, Adrian and Bowlby, Reanne and Brooks, Denise and Carlsen, Rebecca and Dhalla, Noreen and Kasaian, Katayoon and Lee, Darlene and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Robertson, A. Gordon and Schein, Jacqueline E and Sipahimalani, Payal and Thiessen, Nina and Tse, Kane and Wong, Tina and Berger, Ashton C and Beroukhim, Rameen and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cancer cell, ISSN 1535-6108, 04/2018, Volume 33, Issue 4, pp. 721 - 735.e8
genomic | colorectal | epigenetic | tumor | methylation | colon | cancer | stomach | rectum | esophagus | Oncology | Cell Biology | Cancer Research | Life Sciences & Biomedicine | Science & Technology | Gastrointestinal Neoplasms - classification | Microsatellite Instability | Gastrointestinal Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Adenocarcinoma - classification | Epigenesis, Genetic | Humans | Poly-ADP-Ribose Binding Proteins - genetics | Aneuploidy | Male | Gene Regulatory Networks | Heterogeneous-Nuclear Ribonucleoproteins - genetics | DNA Methylation | MutL Protein Homolog 1 - genetics | Female | Adenocarcinoma - genetics | Polymorphism, Single Nucleotide | Mutation | Chromosomal Instability | DNA Polymerase II - genetics | SOX9 Transcription Factor - genetics | Index Medicus | Stomach | Colorectal | Rectum | Tumor | Colon | Epigenetic | Methylation | Genomic | Cancer | Esophagus
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5. Full Text Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
by Linehan, W. Marston and Spellman, Paul T and Ricketts, Christopher J and Creighton, Chad J and Fei, Suzanne S and Davis, Caleb and Wheeler, David A and Murray, Bradley A and Schmidt, Laura and Vocke, Cathy D and Peto, Myron and Al Mamun, Abu Amar M and Shinbrot, Eve and Sethi, Anurag and Brooks, Samira and Rathmell, W. Kimryn and Brooks, Angela N and Hoadley, Katherine A and Robertson, A. Gordon and Brooks, Denise and Bowlby, Reanne and Sadeghi, Sara and Shen, Hui and Weisenberger, Daniel J and Bootwalla, Moiz and Baylin, Stephen B and Laird, Peter W and Cherniack, Andrew D and Saksena, Gordon and Haake, Scott and Li, Jun and Liang, Han and Lu, Yiling and Mills, Gordon B and Akbani, Rehan and Leiserson, Mark D.M and Raphael, Benjamin J and Anur, Pavana and Bottaro, Donald and Albiges, Laurence and Barnabas, Nandita and Choueiri, Toni K and Czerniak, Bogdan and Godwin, Andrew K and Hakimi, A. Ari and Ho, Thai H and Hsieh, James and Ittmann, Michael and Kim, William Y and Krishnan, Bhavani and Merino, Maria J and Shaw, Kenna R. Mills and Reuter, Victor E and Reznik, Ed and Shelley, Carl S and Shuch, Brian and Signoretti, Sabina and Srinivasan, Ramaprasad and Tamboli, Pheroze and Thomas, George and Tickoo, Satish and Burnett, Kenneth and Crain, Daniel and Gardner, Johanna and Lau, Kevin and Mallery, David and Morris, Scott and Paulauskis, Joseph D and Penny, Robert J and Shelton, Candace and Shelton, W. Troy and Sherman, Mark and Thompson, Eric and Yena, Peggy and Avedon, Melissa T and Bowen, Jay and Gastier-Foster, Julie M and Gerken, Mark and Leraas, Kristen M and Lichtenberg, Tara M and Ramirez, Nilsa C and Santos, Tracie and Wise, Lisa and Zmuda, Erik and Demchok, John A and Felau, Ina and Hutter, Carolyn M and Sheth, Margi and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean C and Zhang, Jiashan and Ayala, Brenda and Baboud, Julien and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
The New England journal of medicine, ISSN 0028-4793, 01/2016, Volume 374, Issue 2, pp. 135 - 145
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Proto-Oncogene Proteins c-met - metabolism | RNA, Neoplasm - chemistry | Carcinoma, Papillary - genetics | Kidney Neoplasms - genetics | Humans | Kidney Neoplasms - metabolism | CpG Islands - physiology | Carcinoma, Papillary - metabolism | Proto-Oncogene Proteins c-met - genetics | DNA Methylation | Phenotype | Sequence Analysis, RNA | NF-E2-Related Factor 2 - metabolism | NF-E2-Related Factor 2 - genetics | RNA, Messenger - chemistry | Signal Transduction - physiology | Mutation | Proto-Oncogene Proteins c-met - chemistry | MicroRNAs - chemistry | Care and treatment | Histology | Carcinoma, Renal cell | Research | Gene mutations | Analysis | Phenotypes | Carcinoma | Cell survival | mRNA | Genomes | Antioxidants | Fumarate hydratase | Kidney cancer | DNA methylation | miRNA | Molecular biology | Chromosomes | Clear cell-type renal cell carcinoma | DNA sequencing | CpG islands | Tumors | Index Medicus | Abridged Index Medicus
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