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Nature, ISSN 0028-0836, 2013, Volume 504, Issue 7480, pp. 437 - 440
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 08/2017, Volume 114, Issue 34, pp. E7140 - E7149
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2017, Volume 114, Issue 34, p. E7140
microRNA-146a (miR-146a) has been previously implicated as an essential molecular brake, preventing immune overreaction and malignant transformation by... 
Splenomegaly | Transformation | Genes | Homeostasis | Activation | Epistasis | Genotype & phenotype | Rodents | Bone marrow | Myelopoiesis | IRAK protein | Immune response | TRAF6 protein | MiRNA | Myeloproliferation | Inflammation | Ribonucleic acid--RNA | Biological activity | Hemopoiesis | Studies | Gene silencing | Molecular modelling | Ribonucleic acids | Stem cells | Mice | Aberration | Tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148139
Even when treated with aggressive current therapies, most patients with glioblastoma survive less than two years. Rapid tumor growth, an invasive nature, and... 
TRIAL | CELLS | MELANOMA | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | RECURRENT GLIOBLASTOMA | GROWTH | MICE | OLIGODEOXYNUCLEOTIDE | CANCER | DELIVERY | Inflammation - pathology | Dacarbazine - therapeutic use | Brain Neoplasms - pathology | Polyethylene Glycols - chemistry | Antineoplastic Agents - therapeutic use | Dose-Response Relationship, Drug | Lipids - chemistry | Glioma - pathology | Immunotherapy | Dacarbazine - analogs & derivatives | Female | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Spleen - pathology | Disease Models, Animal | Oligodeoxyribonucleotides - therapeutic use | Neoplasm Invasiveness | Mice, Inbred C57BL | Treatment Outcome | Brain Neoplasms - drug therapy | Animals | Nanotubes, Carbon - chemistry | Cell Line, Tumor | Temozolomide | Glioma - drug therapy | Complications and side effects | Usage | Gliomas | Nanotubes | Dosage and administration | Research | Drug therapy | Brain tumors | Brain cancer | Glioblastoma | Oligonucleotides | Clinical trials | Cytotoxicity | Neurosurgery | Joint surgery | Cancer therapies | Anticancer properties | Toxicology | Blood-brain barrier | Splenocytes | Surgery | Drug dosages | Single wall carbon nanotubes | CpG islands | Medical research | Antigens | Effectiveness | Melanoma | Implantation | Patients | Carbon | Medicine | Chemotherapy | Brain research | Glioma | Nanotechnology | Tumors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2017, Volume 114, Issue 34, pp. E7140 - E7149
microRNA-146a (miR-146a) has been previously implicated as an essential molecular brake, preventing immune overreaction and malignant transformation by... 
miR-146a | IFN-γ | Inflammation | MicroRNA | Traf6 | ACTIVATION | SIGNALING PROTEINS | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | NLRP3 INFLAMMASOME | IFN-gamma | INTERFERON-GAMMA | inflammation | PATHWAY | microRNA | MICE | NF-KAPPA-B | APLASTIC-ANEMIA | RNA sequencing | Immune response | Genetic aspects | Health aspects | Hematopoietic stem cells | Methods | Biological Sciences | PNAS Plus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2018, Volume 24, Issue 23, pp. 6053 - 6065
Purpose: Proliferating cell nuclear antigen (PCNA) plays an essential role in regulating DNA synthesis and repair and is indispensable to cancer cell growth... 
BREAST-CANCER | ACTIVATION | PROGNOSTIC-FACTOR | INHIBITION | CELL NUCLEAR ANTIGEN | MECHANISM | ONCOLOGY | IDENTIFICATION | BINDING | PEPTIDE | DNA-REPLICATION
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2015, Volume 14, Issue 7, pp. 1614 - 1624
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 07/2018
Proliferating cell nuclear antigen (PCNA) plays an essential role in regulating DNA synthesis and repair and is indispensable to cancer cell growth and... 
Journal Article
Toxicologic Pathology, ISSN 0192-6233, 12/2008, Volume 36, Issue 7, pp. 905 - 916
Sunitinib malate (SUTENT) is a multitargeted receptor tyrosine kinase (RTK) inhibitor that is approved multinationally for the treatment of... 
Sunitinib malate | Nonclinical toxicity | Receptor tyrosine kinase inhibitor | Anti-angiogenesis | PANCREATIC ACINAR-CELLS | TUMOR | MECHANISMS | PATHOLOGY | sunitinib malate | nonclinical toxicity | SU11248 | INACTIVATION | receptor tyrosine kinase inhibitor | BLOOD CAPILLARIES | anti-angiogenesis | IN-VIVO | BIOLOGY | TYROSINE KINASE INHIBITOR | TOXICOLOGY | ENDOTHELIAL GROWTH-FACTOR | Adrenal Glands - pathology | Growth Plate - pathology | Pyrroles - pharmacokinetics | Recovery of Function - drug effects | Incisor - pathology | Macaca fascicularis | Male | Antineoplastic Agents - administration & dosage | Gastrointestinal Tract - pathology | Indoles - administration & dosage | Antineoplastic Agents - toxicity | Neovascularization, Pathologic - pathology | Pyrroles - administration & dosage | Growth Plate - drug effects | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Ovary - drug effects | Antineoplastic Agents - pharmacokinetics | Adrenal Glands - drug effects | Lymphoid Tissue - drug effects | Bone Marrow - drug effects | Ovary - pathology | Incisor - drug effects | Pancreas - drug effects | Pancreas - pathology | Rats | Gastrointestinal Tract - drug effects | Indoles - toxicity | Neovascularization, Pathologic - chemically induced | Microscopy, Electron | Rats, Sprague-Dawley | Toxicity Tests, Chronic - methods | Lymphoid Tissue - pathology | Animals | Signal Transduction - drug effects | Pyrroles - toxicity | Bone Marrow - pathology | Indoles - pharmacokinetics | Index Medicus
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 02/2015, Volume 25, Issue 4, pp. 767 - 774
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2005, Volume 174, Issue 11, pp. 7141 - 7146
Regulatory CD4 super(+)CD25 super(+) T cells (Tregs) suppress autoimmune and inflammatory diseases through mechanisms that are only partly understood. Previous... 
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2015, Volume 25, Issue 4, pp. 767 - 774
The β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) is one of the most hotly pursued targets for the treatment of Alzheimer’s disease. We used... 
Alzheimer’s disease (AD) | Aminooxazoline | 3-Azaxanthene | Amyloid | β-Secretase (BACE1) | Xanthene | Aβ peptides
Journal Article
Toxicologic Pathology, ISSN 0192-6233, 03/2007, Volume 35, Issue 2, p. 325
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2001, Volume 175, Issue 3, pp. 243 - 252
Journal Article
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