X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (13) 13
cystic fibrosis (9) 9
humans (9) 9
organoids (8) 8
journal article (7) 7
mutation (6) 6
animals (5) 5
cftr (5) 5
mice (5) 5
analysis (4) 4
cell line (4) 4
cystic fibrosis - drug therapy (4) 4
cystic fibrosis - genetics (4) 4
cystic fibrosis transmembrane conductance regulator - genetics (4) 4
cystic fibrosis transmembrane conductance regulator - metabolism (4) 4
gene (4) 4
identification (4) 4
ivacaftor (4) 4
lumacaftor (4) 4
respiratory system (4) 4
biopsy (3) 3
cell biology (3) 3
colon (3) 3
cystic fibrosis - metabolism (3) 3
disease (3) 3
lung-disease (3) 3
medicine (3) 3
organoids - drug effects (3) 3
organoids - metabolism (3) 3
potentiator (3) 3
stem-cells (3) 3
virology (3) 3
viruses (3) 3
aminophenols - pharmacology (2) 2
aminopyridines - pharmacology (2) 2
benzodioxoles - pharmacology (2) 2
biochemistry, genetics and molecular biology (2) 2
biological assay - methods (2) 2
cells (2) 2
cells, cultured (2) 2
cftr function (2) 2
cftr potentiator (2) 2
chlorides - metabolism (2) 2
coronavirus - genetics (2) 2
coronavirus - metabolism (2) 2
cultures (2) 2
diagnosis (2) 2
drug response (2) 2
efficacy (2) 2
female (2) 2
forskolin (2) 2
g551d (2) 2
genetic aspects (2) 2
genome and regulation of viral gene expression (2) 2
genome replication and regulation of viral gene expression (2) 2
genotype (2) 2
human colorectal organoids (2) 2
in-vitro (2) 2
infected-cells (2) 2
intestinal organoids (2) 2
ion transport (2) 2
issue 120 (2) 2
kidneys (2) 2
mechanism (2) 2
medicine, research & experimental (2) 2
microscopy, confocal - methods (2) 2
murine hepatitis-virus (2) 2
organoid swelling (2) 2
organoids - pathology (2) 2
personalized treatment (2) 2
phe508del cftr (2) 2
phenotype (2) 2
predicting (2) 2
primary cell culture (2) 2
quinolones - pharmacology (2) 2
rectum - pathology (2) 2
replication-transcription complexes (2) 2
respiratory syndrome coronavirus (2) 2
safety (2) 2
stem cell cultures (2) 2
stem cells (2) 2
sweat chloride (2) 2
tezacaftor-ivacaftor (2) 2
three dimensional models (2) 2
topology (2) 2
transmembrane conductance regulator (2) 2
viral nonstructural proteins - metabolism (2) 2
abstracts (1) 1
acute renal failure (1) 1
administration, oral (1) 1
adrenergic beta-2 receptor agonists - pharmacology (1) 1
adult (1) 1
adult stem cells - cytology (1) 1
adult stem cells - metabolism (1) 1
adult stem cells/cytology (1) 1
albuterol - administration & dosage (1) 1
amino acid sequence (1) 1
artificial gene fusion (1) 1
bacteriophage-t7 rna-polymerase (1) 1
biochemical phenomena, metabolism, and nutrition (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Science translational medicine, ISSN 1946-6234, 3/2019, Volume 11, Issue 485
Cystic fibrosis (CF) is a multi-organ disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). In patients with CF,... 
Journal Article
Jove-Journal of visualized experiments, ISSN 1940-087X, 02/2017, Volume 2017, Issue 120
Recently-developed cystic fibrosis transmembrane conductance regulator (CFTR)-modulating drugs correct surface expression and/or function of the mutant CFTR... 
Immunology and Microbiology(all) | Cystic fibrosis | Ivacaftor (VX-770) | Neuroscience(all) | Human colorectal organoids | Medicine | Organoid swelling | Issue 120 | Biopsy | Forskolin | Chemical Engineering(all) | Biochemistry, Genetics and Molecular Biology(all) | CFTR function | Lumacaftor (VX-809) | Primary cell culture
Journal Article
Journal of Cystic Fibrosis, ISSN 1569-1993, 05/2018, Volume 17, Issue 3, pp. 316 - 324
New functional assays using primary human intestinal adult stem cell cultures can be valuable tools to study epithelial defects in human diseases such as... 
Donor-matched | Organoids | Monolayers | Electrophysiology | Biopsies | Differentiation | CFTR | TRANSMEMBRANE CONDUCTANCE REGULATOR | GENE | RESPIRATORY SYSTEM | DISEASE | Histamine | Medical research | Stem cells | Medicine, Experimental | Cystic fibrosis | Cyclic adenylic acid | Comparative analysis | Sugars | Monosaccharides
Journal Article
Science Translational Medicine, ISSN 1946-6234, 2019, Volume 11, Issue 485, p. eaau7531
Cystic fibrosis (CF) is a multiorgan disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). In patients with CF,... 
MEDICINE, RESEARCH & EXPERIMENTAL | DISRUPTION | JUVENILE | GENE | PHENOTYPE | CFTR POTENTIATOR | CELL BIOLOGY
Journal Article
Cell reports, ISSN 2211-1247, 02/2019, Volume 26, Issue 7, pp. 1701 - 1708.e3
In vitro drug tests using patient-derived stem cell cultures offer opportunities to individually select efficacious treatments. Here, we provide a study that... 
SWEAT CHLORIDE | EFFICACY | GENE | SAFETY | TEZACAFTOR-IVACAFTOR | LUNG-DISEASE | COLON | G551D | IDENTIFICATION | POTENTIATOR
Journal Article
Cell Reports, ISSN 2211-1247, 2019, Volume 26, Issue 7, pp. 1701 - 1708.e3
Berkers et al. demonstrate that stem cell cultures (organoids) can be a tool for personalized medicine. They show a high correlation between in vitro and in... 
Journal Article
by de Vette, Ivar and Lombardo, Angelo and Berkhout, Ben and Vervoordeldonk, Margriet and Dekkers, Johanna F and Kruisselbrink, Evelien and Vonk, Annelotte M and de Jonge, Hugo R and de Winter, Karin M and de Groot, – and Janssens, Hettie M and Bronsveld, Inez and Nieuwenhuis, Edward E.S and Houwen, Roderick H.J and Vleggaar, Frank P and Escher, Hankje C and Clevers, Hans and van der Ent, Cornelis K and Buckland, Karen and Rivat, Christine and Himoudi, Nourredine and Gilmour, Kimberly and Booth, Claire and Cornetta, Kenneth and Kohn, Don B and Carbonaro, Denise and Paruzynski, Anna and Schmidt, Manfred and Thrasher, Adrian J and Schaffer, David and Hwang, Tae-Ho and Zinn, E and Khaychuk, V and Sarkar, D and Carvalho, L and Pacouret, S and Morris, H and Plovie, E and van Gent, Michiel and Gram, Anna and Boer, Ingrid and Horst, Danielle and Zaldumbide, Arnaud and Hoeben, Rob and Wiertz, Emmanuel and Maring, J and Smits, AM and Ouyang, Hong and Lin, Ying and Wang, Yujuan and Cai, Humim and Li, Gen and Patel, Sherrina and Zhu, Jie and Lin, Danni and Wen, Cindy and Zhu, Jin and Tsaalbi-Shtylik, Anastasia and Martín-Pardillos, Ana and Ferras, Cristina and Verspuy, Johan and Speksnijder, Ewoud and Jansen, Jacob and Peng, Kah Whye and Federspiel, Mark and Naik, Shruthi and Ruiz, Autumn and Lacy, Martha and Dispenzieri, Angela and O'Donovan, Liz and Arzumanov, Andrey A and Rahim, A.A and Burke, D.G and Buckley, S.M and Cullen, E and Mukherji, S and Mills, K and Sirka, E and Herbert, B and Karlsson, S and Hughes, D.A and Mehta, A.B and Howe, S.J and Heales, S and Cooper, J.D and Cheng, S.H and van Til, Niek P and Liang, Q and Stok, M and Wagemaker, G and Reiss, Ulrike M and Tuddenham, Edward G.D and Nienhuis, Arthur W and Davidoff, Andrew M and Meneghini, V and Lattanzi, A and Tiradani, L and Bravo, G and Morena, F and Martino, S and ...
Human Gene Therapy, ISSN 1043-0342, 11/2014, Volume 25, Issue 11, pp. A1 - A121
Journal Article
Life Science Alliance, ISSN 2575-1077, 01/2019, Volume 2, Issue 1, p. e201800172
Cystic fibrosis is caused by mutations in the CFTR gene, which are subdivided into six classes. Mutants of classes III and IV reach the cell surface but have... 
Plant Science | Ecology | Biochemistry, Genetics and Molecular Biology (miscellaneous) | Health, Toxicology and Mutagenesis
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.