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Nature Biotechnology, ISSN 1087-0156, 04/2018, Volume 36, Issue 4, pp. 1 - 10
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Degeneration | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e15009 - e15009
Melanopsin photoreception plays a vital role in irradiance detection for non-image forming responses to light. However, little is known about the involvement... 
SUPERIOR COLLICULUS | PUPILLARY CONSTRICTION | RETINAL GANGLION-CELLS | NON-ROD | VISUAL-CORTEX | MOUSE MODEL | BIOLOGY | NON-CONE | OCULAR PHOTORECEPTORS | RETROSPLENIAL CORTEX | MICE LACKING | Immunohistochemistry | Retina - metabolism | Visual Cortex - radiation effects | Humans | Channelrhodopsins | Motor Activity - drug effects | Rod Opsins - physiology | Mice, 129 Strain | Avoidance Learning - radiation effects | Motor Activity - radiation effects | Rod Opsins - genetics | Transducin - physiology | GTP-Binding Protein alpha Subunits - physiology | Light | Electroretinography | Transducin - genetics | Mice, Inbred C57BL | Cyclic Nucleotide-Gated Cation Channels - genetics | Proto-Oncogene Proteins c-fos - metabolism | Cyclic Nucleotide-Gated Cation Channels - physiology | Atropine - pharmacology | GTP-Binding Protein alpha Subunits - genetics | Parasympatholytics - pharmacology | Mice, Knockout | Regression Analysis | Animals | Avoidance Learning - drug effects | Mice | Kinetics | Visual Cortex - metabolism | Genetically modified organisms | Photoreception | Migraine | Spatial discrimination | Retina | Biology | Interdisciplinary aspects | Irradiance | Melanopsin | Image detection | Studies | Signaling | Brain research | Rodents | Aversion | Atropine | Physiology | Trends | Genetic modification | Animal cognition | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e15063 - e15063
The mammalian visual system relies upon light detection by outer-retinal rod/cone photoreceptors and melanopsin-expressing retinal ganglion cells. Gnat1(-/-);... 
ALPHA-SUBUNIT | SIGNALING PATHWAY | MELANOPSIN | ROD TRANSDUCIN | MOUSE | LIGHT | BIOLOGY | KNOCKOUT MICE | CONE TRANSDUCIN | TRANSGENIC MICE | PHOTORECEPTORS | Retina - metabolism | Adaptation, Ocular - drug effects | Male | Light Signal Transduction - genetics | Retinal Rod Photoreceptor Cells - metabolism | Geniculate Bodies - physiology | Visual Cortex - physiology | Rod Opsins - genetics | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Rod Opsins - metabolism | Transducin - metabolism | Light Signal Transduction - physiology | Cyclic Nucleotide-Gated Cation Channels - metabolism | Electroretinography | Transducin - genetics | GTP-Binding Protein alpha Subunits - metabolism | Visual Perception - genetics | Visual Perception - physiology | Geniculate Bodies - metabolism | Cyclic Nucleotide-Gated Cation Channels - genetics | Phosphodiesterase Inhibitors - pharmacology | GTP-Binding Protein alpha Subunits - genetics | Mice, Knockout | Visual Cortex - enzymology | Retina - physiology | Animals | Retinal Rod Photoreceptor Cells - physiology | Mice | Visual Cortex - metabolism | Cornea | Electromagnetic absorption | Transducin | Retina | Melanopsin | Critical components | Signal transduction | Visual system | Missense mutation | Transgenic animals | Cascades | Rodents | Life sciences | Photoreception | Cortex (visual) | Mammals | Light effects | Phospholipase C | Electroretinograms | Retinal ganglion cells | Phospholipase | Phototransduction | Silence | Opsins | Photoreceptors | Mutation | Lateral geniculate nucleus | Disruption | Index Medicus
Journal Article
Experimental Eye Research, ISSN 0014-4835, 02/2014, Volume 119, pp. 8 - 18
Journal Article
Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 09/2018, Volume 12, pp. 730 - 740
Leber congenital amaurosis type 10 (LCA10) is a severe inherited retinal dystrophy associated with mutations in . The deep intronic c.2991+1655A>G mutation in... 
retinal dystrophy | stem cell | QR-110 | therapy | oligonucleotide | organoid | RETINAL DEGENERATION | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | LEBER CONGENITAL AMAUROSIS | IN-VITRO | OPTIC CUPS | MUTATION | GENE-THERAPY | ANTISENSE OLIGONUCLEOTIDES | DISEASE MECHANISMS | PRIMARY CILIA
Journal Article
Experimental Neurology, ISSN 0014-4886, 2008, Volume 214, Issue 2, pp. 347 - 361
Journal Article