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chemistry, medicinal (262) 262
humans (234) 234
carbonic anhydrase inhibitors - chemistry (195) 195
carbonic anhydrase (193) 193
carbonic anhydrases - metabolism (190) 190
carbonic anhydrase inhibitors - pharmacology (186) 186
structure-activity relationship (170) 170
chemistry, organic (152) 152
biochemistry & molecular biology (130) 130
sulfonamides (119) 119
carbonic anhydrase inhibitors - chemical synthesis (117) 117
carbonic anhydrases - chemistry (115) 115
sulfonamides - chemistry (112) 112
sulfonamides - pharmacology (96) 96
molecular structure (80) 80
sulfonamide (79) 79
therapeutic applications (77) 77
isoenzymes - antagonists & inhibitors (74) 74
kinetics (70) 70
amino acid sequence (68) 68
sulfonamides - chemical synthesis (66) 66
dose-response relationship, drug (61) 61
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molecular sequence data (60) 60
animals (59) 59
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carbonic anhydrase ix (51) 51
derivatives (49) 49
isoenzymes - metabolism (49) 49
isozyme-ii (49) 49
crystal-structure (48) 48
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expression (44) 44
activators (42) 42
binding (42) 42
isoenzymes (42) 42
cancer (41) 41
carbonic anhydrases - genetics (41) 41
mycobacterium-tuberculosis (40) 40
models, molecular (38) 38
transmembrane (37) 37
carbonic anhydrase ii - antagonists & inhibitors (36) 36
drug targets (36) 36
helicobacter-pylori (36) 36
hypoxia (35) 35
metalloenzymes (34) 34
protein binding (34) 34
carbonic anhydrase inhibitors - metabolism (33) 33
inhibitor (33) 33
antigens, neoplasm - metabolism (31) 31
sequence alignment (31) 31
carbonic anhydrase i - antagonists & inhibitors (30) 30
cloning (30) 30
cryptococcus-neoformans (30) 30
active-site (29) 29
anions (29) 29
isoenzymes - chemistry (29) 29
carbonic anhydrase ii - metabolism (28) 28
cloning, molecular (28) 28
phylogeny (28) 28
anion (27) 27
ophthalmic drugs (27) 27
crystallography, x-ray (26) 26
heterocyclic sulfonamides (26) 26
carbonic anhydrases - drug effects (25) 25
catalytic domain (25) 25
anion inhibition (24) 24
anions - chemistry (24) 24
antigens, neoplasm - chemistry (24) 24
carbonic anhydrase i - metabolism (24) 24
class enzyme (24) 24
male (24) 24
organic chemistry (24) 24
recombinant proteins - chemistry (24) 24
tumors (24) 24
cytosol - enzymology (23) 23
drug discovery (23) 23
carbonic anhydrase ii - chemistry (22) 22
catalysis (22) 22
neoplasms - enzymology (22) 22
protein isoforms - metabolism (22) 22
analysis (21) 21
carbon dioxide (21) 21
chemical sciences (21) 21
diatom thalassiosira-weissflogii (21) 21
enzyme activation - drug effects (21) 21
therapy (21) 21
acetazolamide (20) 20
coumarins (20) 20
plasmodium-falciparum (20) 20
sulfonic acids - chemistry (20) 20
antineoplastic agents - chemistry (19) 19
drugs (19) 19
enzyme (19) 19
female (19) 19
pharmacology & pharmacy (19) 19
porphyromonas-gingivalis (19) 19
carbonic anhydrase i - chemistry (18) 18
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by Kirmeier, Eva and Eriksson, Lars I and Lewald, Heidrun and Jonsson Fagerlund, Malin and Hoeft, Andreas and Hollmann, Markus and Meistelman, Claude and Hunter, Jennifer M and Ulm, Kurt and Blobner, Manfred and Abad Gurumeta, Alfredo and Abernethy, Caroline and Abigail, Patrick and Achaibar, Kira and Adam, Emily and Afshari, Arash and Agudelo Montoya, M. Elizabeth and Akgün, Fatma Nur and Aletti, Gabriele and Alkış, Neslihan and Allan, Katie and Allan, Ashley and Allaouchiche, Bernard and Allcock, Clare and Almasy, Emoke and Amey, Isobel and Amigoni, Maria and Andersen, Elin and Andersson, Peder and Anipchenko, Natalya and Antunes, Pedro and Armstrong, Earlene and Aslam, Tayyba Naz and Aslin, Bjorn and Assunção, José Pedro and Ausserer, Julia and Avvai, Mary and Awad, Nahla and Ayas Montero, Begoña and Ayuso, Mercedes and Azevedo, Patricia and Badarau, Victoria and Badescu, Roxana and Baiardo Redaelli, Martina and Baird, Yolanda and Baird, Colin and Baker, Tim and Balaji, Packianathaswamy and Bălan, Cristina and Balandin, Alina and Balescu-Arion, Carmen and Baliuliene, Vilda and Baltasar Isabel, Jorge and Baluch, Saif Nasr and Bandrabur, Daniela and Bankewitz, Carla and Barber, Katrina and Barbera, Francesco and Barcraft-Barnes, Helena and Barletti, Valentina and Barnett, Gill and Baron, Kirsty and Barros, Ana and Barsan, Victoria and Bartlett, Pauline and Batistaki, Chrysanthi and Baumgarten, Georg and Baytas, Volkan and Beauchamp, Nigel and Becerra Cayetano, Isabel A and Bell, Stephanie and Bellandi, Mattia and Belletti, Alessandro and Belmonte Cuenca, Julio and Benitez-Cano, Adela and Beretta, Luigi and Berger, Marc and Bergmann, Nicole and Bergmark, Kristina and Bermudez Lopez, Maria and Bernotaite, Monika and Beurskens, Charlotte and Bidd, Heena and Bifulco, Francesca and Bignami, Elena and Bilic, Aleksandar and Bilskiene, Diana and Bischoff, Petra and Bishop, Luke and Bjonness, Therese and Blaylock, Hether and Blethyn, Kate and Blincoe, Thomas and Blokhin, Ivan and Blunt, Nadia and Boer, Christa and Bois, Grégory and Bonicolini, Eleonora and Booth, Joanna and Borecka-Kedzierska, Miroslawa and ... and POPULAR Contributors
The Lancet Respiratory Medicine, ISSN 2213-2600, 02/2019, Volume 7, Issue 2, pp. 129 - 140
Results from retrospective studies suggest that use of neuromuscular blocking agents during general anaesthesia might be linked to postoperative pulmonary... 
SURGERY | TRACHEAL INTUBATION | SURGICAL CONDITIONS | EVENTS | RESPIRATORY SYSTEM | RISK | BLOCKADE | ASSOCIATION | NEUROMUSCULAR-BLOCKING-AGENTS | RESIDUAL PARALYSIS | REVERSAL | CRITICAL CARE MEDICINE
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 12/2014, Volume 51, Issue 2, pp. 302 - 305
A structural study of the adduct which 2-benzylsulfinylbenzoic acid forms with human carbonic anhydrase II is reported, showing a binding mode completely... 
Binding | Enzymes | Inhibitors | Carbonic anhydrase | Pocket | Carboxylates | Adducts
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 03/2013, Volume 21, Issue 6, pp. 1465 - 1469
We report the biochemical characterization of a new carbonic anhydrase (CA, EC 4.2.1.1), named SazCA, identified by translated genome inspection in... 
Esterase | Protein purification | Fastest enzyme | Thermostable α-CA | hydrase | Metalloenzymes
Journal Article
Journal Article
ChemMedChem, ISSN 1860-7179, 10/2018, Volume 13, Issue 19, pp. 2024 - 2029
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 9/2018, Volume 75, Issue 17, pp. 3283 - 3296
Journal Article