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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 14, pp. 6328 - 6333
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2013, Volume 105, Issue 17, pp. 1322 - 1331
Glioblastomas exhibit a high level of chemotherapeutic resistance, including to the antimitotic agents vincristine and taxol. During the mitotic agent-induced... 
MITOSIS | SPINDLE-CHECKPOINT | MECHANISM | ONCOLOGY | GLIOMA | KINASE | PROLIFERATION | HUMAN CANCER-CELLS | MITOTIC CHECKPOINT | MICROTUBULE DYNAMICS | SMALL-MOLECULE INHIBITOR | Up-Regulation | RNA Interference - drug effects | Frozen Sections | ortho-Aminobenzoates - pharmacology | United States | Humans | M Phase Cell Cycle Checkpoints - genetics | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Cell Cycle Proteins - antagonists & inhibitors | Antineoplastic Agents, Phytogenic - administration & dosage | Netherlands | 2-Aminopurine - analogs & derivatives | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Vincristine - administration & dosage | France | Paclitaxel - administration & dosage | Cell Survival - drug effects | M Phase Cell Cycle Checkpoints - drug effects | 2-Aminopurine - pharmacology | Xenograft Model Antitumor Assays | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Antimitotic Agents - pharmacology | Mice | Glioblastoma - drug therapy | Glioblastoma - mortality | Protein-Tyrosine Kinases - antagonists & inhibitors | Antimitotic agents | Care and treatment | Physiological aspects | Drug targeting | Dosage and administration | Research | Antineoplastic agents | Glioblastoma multiforme | Protein kinases | Cell division | Inhibitor drugs | Kinases | Gene expression | Tumors | Index Medicus | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
PLoS One, ISSN 1932-6203, 2011, Volume 6, Issue 1, pp. e16282 - e16282
Angiogenesis is a balanced process controlled by pro-and anti-angiogenic molecules of which the regulation is not fully understood. Besides classical gene... 
HISTONE METHYLTRANSFERASE ACTIVITY | OVEREXPRESSION | COMPLEX | ANGIOGENESIS | BIOLOGY | H3 LYSINE-27 METHYLATION | GROUP PROTEIN EZH2 | GENE-EXPRESSION | MICRORNAS | TUMOR-GROWTH | CANCER | Endothelial Cells - metabolism | Humans | Angiogenic Proteins - physiology | Cells, Cultured | Transcription Factors - biosynthesis | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Down-Regulation - genetics | Enhancer of Zeste Homolog 2 Protein | Polycomb Repressive Complex 2 | Animals | Mice | MicroRNAs - genetics | Histones - metabolism | Methylation | DNA-Binding Proteins - biosynthesis | Vascular Endothelial Growth Factor A - physiology | Endothelial Cells - physiology | Neovascularization, Physiologic | Epigenetic inheritance | Enzymes | MicroRNA | Gliomas | Genes | Neovascularization | Genetic transcription | Health aspects | Vascular endothelial growth factor | Endothelium | Post-transcription | Pediatrics | Regulations | Regulators | Neurosciences | Chromatin | Toxicity | Gene regulation | Glioblastoma | Methyltransferase | Multiple myeloma | Oncology | Neurosurgery | Blood | Medical schools | Vascularization | Proteins | Angiogenesis | Cell growth | Inhibition | Medical research | Hematology | Blood vessels | Cultures | siRNA | Breast cancer | Gene expression | Endothelial cells | Polycomb group proteins | Gene silencing | Neurology | Signaling | Brain research | Lysine | Stem cells | Aberration | Bayesian analysis | Histone H3 | Index Medicus | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medicinsk bioteknologi
Journal Article
Cancer Research, ISSN 0008-5472, 2011, Volume 71, Issue 3, pp. 852 - 861
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 18, Issue 3, pp. 244 - 257
Journal Article
Cancer Cell, ISSN 1535-6108, 2008, Volume 14, Issue 5, pp. 382 - 393
A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here, we demonstrate that a small regulatory microRNA, miR-296,... 
CELLCYCLE | THERAPY | ONCOLOGY | VASCULAR INTEGRITY | IN-VIVO | GENE-EXPRESSION | DEGRADATION | TARGETS | OCULAR NEOVASCULARIZATION | TUMOR ANGIOGENESIS | MICRORNAS | CANCER | CELL BIOLOGY | Endothelium, Vascular - cytology | Luciferases - metabolism | MicroRNAs - antagonists & inhibitors | Humans | Neovascularization, Pathologic | Molecular Sequence Data | MicroRNAs - metabolism | Brain Neoplasms - blood supply | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Brain Neoplasms - metabolism | Glioma - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Kidney - metabolism | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Oligonucleotides - pharmacology | Base Sequence | RNA, Messenger - antagonists & inhibitors | Glioma - therapy | Umbilical Veins - cytology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Signal Transduction | Endosomal Sorting Complexes Required for Transport | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Kidney - cytology | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Homology, Nucleic Acid | Blotting, Western | Hepatocyte Growth Factor - metabolism | Glioma - blood supply | Xenograft Model Antitumor Assays | Magnetic Resonance Imaging | Animals | Endothelium, Vascular - metabolism | Brain Neoplasms - therapy | Fluorescent Antibody Technique | Mice | MicroRNAs - genetics | Cell Movement | Umbilical Veins - metabolism | Tyrosine | Medical colleges | Neurosciences | Messenger RNA | Gliomas | Oncology, Experimental | Brain tumors | Research | Growth factors | Cancer | Endothelium | Index Medicus | PDGFR | VEGFR | miRNA | cancer | HGS | angiogenesis
Journal Article