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NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 12/2015, Volume 373, Issue 24, pp. 2386 - 2388
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2016, Volume 115, Issue 11, pp. 813 - 822
Summary HIT is an acquired antibody-mediated disorder strongly associated with thrombosis, including microthrombosis secondary to disseminated intravascular... 
Theme Issue Article | Thrombosis | Platelet activation | Heparin-induced thrombocytopenia | ANTIBODIES | VENOUS LIMB GANGRENE | FONDAPARINUX | platelet activation | WARFARIN THROMBOPROPHYLAXIS | SKIN-LESIONS | PROPHYLAXIS | thrombosis | ORTHOPEDIC-SURGERY | MOLECULAR-WEIGHT HEPARIN | PERIPHERAL VASCULAR DISEASE | POSTTRANSFUSION PURPURA | HEMATOLOGY
Journal Article
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, ISSN 1520-4391, 2011, Volume 2011, Issue 1, pp. 143 - 149
Heparin-induced thrombocytopenia (HIT) is a prothrombotic drug reaction caused by platelet-activating IgG antibodies that recognize platelet factor 4... 
HEMATOLOGY | EDUCATION, SCIENTIFIC DISCIPLINES | Thrombocytopenia - drug therapy | Antithrombins - therapeutic use | Humans | Platelet Activation - immunology | Antibodies - immunology | Thrombocytopenia - diagnosis | Thrombocytopenia - chemically induced | Heparin - adverse effects | Immunoenzyme Techniques
Journal Article
Blood, ISSN 0006-4971, 12/2018, Volume 132, Issue 23, pp. 2421 - 2422
In this issue of Blood, Khandelwal and colleagues show that platelet factor 4 (PF4)/heparin complexes trigger complement activation (classical pathway) through... 
HEMATOLOGY
Journal Article
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 03/2007, Volume 356, Issue 9, pp. 891 - 893
Journal Article
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2017, Volume 70, Issue 21, pp. 2649 - 2651
[...]my colleagues and I (4) reported a retrospective analysis of 16 patients with well-documented HIT who were treated with fondaparinux: none of our 16... 
fondaparinux | heparin-induced thrombocytopenia | ANTIBODIES | SURGERY | HIT | CARDIAC & CARDIOVASCULAR SYSTEMS | ORAL ANTICOAGULANTS | CASE SERIES | EXPERIENCE | Literature reviews | Studies | Thrombocytopenia | Anticoagulants | Immunoglobulins | Side effects | Blood platelets | Heparin | Patients | Thrombosis | Catheters | Regulatory approval
Journal Article
CRITICAL CARE CLINICS, ISSN 0749-0704, 10/2011, Volume 27, Issue 4, pp. 805 - 805
Journal Article
Blood, ISSN 0006-4971, 10/2016, Volume 128, Issue 14, pp. 1781 - 1782
In this issue of Blood, Khandelwal et al show that B cells bind platelet factor 4 (PF4)/heparin complexes in a non-antigen-specific fashion, mediated by... 
ANTIBODIES | HEMATOLOGY | HEPARIN-INDUCED THROMBOCYTOPENIA | Thrombocytopenia | B-Lymphocytes | Heparin | Humans | Platelet Factor 4
Journal Article
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, ISSN 1538-7933, 02/2016, Volume 14, Issue 2, pp. 231 - 235
For unknown reasons, a small minority of critically ill patients with septic or cardiogenic shock, multiorgan failure, and disseminated intravascular... 
acute | ACTIVATION | SYMMETRICAL PERIPHERAL GANGRENE | antithrombin III | HEPARIN-INDUCED THROMBOCYTOPENIA | COAGULOPATHY | MECHANISMS | FAILURE | PATHOGENESIS | liver failure | THERAPY | gangrene | ANTITHROMBIN | PERIPHERAL VASCULAR DISEASE | protein C | HEMATOLOGY | disseminated intravascular coagulation
Journal Article
ANNALS OF THORACIC SURGERY, ISSN 0003-4975, 12/2003, Volume 76, Issue 6, pp. 2121 - 2131
Unfractionated heparin given during cardiopulmonary bypass is remarkably immunogenic, as 25% to 50% of postcardiac surgery patients develop heparin-dependent... 
SURGERY | RECOMBINANT HIRUDIN | CARDIAC & CARDIOVASCULAR SYSTEMS | DIFFERENT FILTER SYSTEMS | ECARIN CLOTTING TIME | EXTRACORPOREAL-CIRCULATION | CARDIOPULMONARY BYPASS-SURGERY | PORCINE HEPARIN | RESPIRATORY SYSTEM | MOLECULAR-WEIGHT HEPARIN | CARDIOVASCULAR-SURGERY | OPEN-HEART-SURGERY | UNFRACTIONATED HEPARIN
Journal Article