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PLoS ONE, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, p. e9367
Background: Mitochondrial dysfunction and degradation takes a central role in current paradigms of neurodegeneration in Parkinson's disease (PD). Loss of DJ-1... 
PINK1 | FUSION | GENE | MULTIDISCIPLINARY SCIENCES | ENERGETIC DEPRESSION | CYSTEINE-SULFINIC ACID | MUSCLE | DEGRADATION | MUTATIONS | PATHOLOGY | FISSION | Oncogene Proteins - genetics | Phosphorylation | Reactive Oxygen Species - metabolism | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy | Fibroblasts - ultrastructure | Lysosomes - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Fibroblasts - metabolism | Parkinson Disease - pathology | Oncogene Proteins - metabolism | Oxidative Phosphorylation | Mitochondria - metabolism | Parkinson Disease - genetics | Microscopy, Electron | Blotting, Western | Mice, Knockout | Peroxiredoxins | Lysosomes - ultrastructure | Protein Deglycase DJ-1 | Animals | Fibroblasts - cytology | Mice | Mutation | Mitogen-Activated Protein Kinase 1 - metabolism | Genes | Genetic aspects | Oxidative stress | Cell culture | Reactive oxygen species | Animal models | Parkinson's disease | Laboratories | Downstream effects | Parkinsons disease | Homeostasis | Lysosomes | Kinases | Accumulation | Degradation | Proteins | Mitochondria | Neurodegeneration | Penicillin | Fibroblasts | Aging | Physiology | Membrane potential | Movement disorders | Neurodegenerative diseases | Extracellular signal-regulated kinase | Organelles | PARK7 protein | Neurology | Brain research | Hypoxia | Electron transport | Respiration | Alzheimers disease | Phagocytosis | Apoptosis | Integrity
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2007, Volume 282, Issue 18, pp. 13680 - 13691
Mutations in the PARK7 gene encoding DJ-1 cause autosomal recessive Parkinson disease. The most deleterious point mutation is the L166P substitution, which... 
APOPTOSIS | OXIDATIVE STRESS | RESOLUTION CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | FAMILIAL PARKINSONS-DISEASE | ALPHA-SYNUCLEIN | TUMOR-SUPPRESSOR PTEN | DROSOPHILA DJ-1 | EARLY-ONSET PARKINSONISM | CELL-DEATH | Oncogene Proteins - genetics | Oxidants - pharmacology | Apoptosis - drug effects | Humans | Protein Processing, Post-Translational - genetics | Cell Survival - genetics | Apoptosis - genetics | Structure-Activity Relationship | Mutation, Missense | PC12 Cells | Embryo, Mammalian - metabolism | Proto-Oncogene Proteins c-akt - genetics | Protein Processing, Post-Translational - drug effects | Cytoprotection - drug effects | Oncogene Proteins - biosynthesis | Parkinson Disease - metabolism | MAP Kinase Kinase Kinase 5 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Fibroblasts - metabolism | Cell Survival - drug effects | Mutagenesis, Site-Directed | MAP Kinase Kinase Kinase 5 - genetics | Hydrogen Peroxide - pharmacology | Rats | Protein Structure, Tertiary - genetics | Signal Transduction - genetics | Parkinson Disease - genetics | Protein Folding | Mice, Knockout | Peroxiredoxins | Protein Deglycase DJ-1 | Animals | Signal Transduction - drug effects | Cytoprotection - genetics | Mice | Amino Acid Motifs - genetics
Journal Article
FASEB Journal, ISSN 0892-6638, 2009, Volume 23, Issue 8, pp. 2478 - 2489
The Parkinson's disease (PD)-associated gene DJ-1 mediates direct neuroprotection. The up-regulation of DJ-1 in reactive astrocytes also suggests a role in... 
Lipopolysaccharide | Mitogen-activated protein kinase | Neuroinflammation | Nitric oxide synthase | Toll-like receptor signaling | LOCALIZATION | OXIDATIVE STRESS | PROTEIN STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROPROTECTION | CELL BIOLOGY | mitogen-activated protein kinase | neuroinflammation | IN-VIVO | BIOLOGY | NITRIC-OXIDE | nitric oxide synthase | MUTATIONS | lipopolysaccharide | DJ-1-DEFICIENT MICE | EXPRESSION | Inflammation - pathology | Oncogene Proteins - genetics | Nitric Oxide Synthase Type II - biosynthesis | Apoptosis - drug effects | Astrocytes - pathology | DNA, Complementary - genetics | Parkinsonian Disorders - metabolism | Inflammation - metabolism | Cyclooxygenase 2 - genetics | Base Sequence | Intercellular Adhesion Molecule-1 - biosynthesis | Toll-Like Receptor 4 - agonists | Parkinsonian Disorders - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Astrocytes - drug effects | Nitric Oxide - biosynthesis | Lipopolysaccharides - toxicity | Interleukin-6 - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Mice, Knockout | Peroxiredoxins | Protein Deglycase DJ-1 | Animals | Parkinsonian Disorders - pathology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Oncogene Proteins - deficiency | Mice | Pyridines - pharmacology | Astrocytes - metabolism | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 2646 - 2646
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 01/2012, Volume 26, Issue 5, pp. 1799 - 1809
Impaired insulin action in the brain represents an early step in the progression toward type 2 diabetes, and elevated levels of saturated free fatty acids are... 
Journal Article
The Journal of Biological Chemistry, ISSN 0021-9258, 5/2009, Volume 284, Issue 21, pp. 14245 - 14257
Parkinson disease (PD)-associated genomic deletions and the destabilizing L166P point mutation lead to loss of the cytoprotective DJ-1 protein. The effects of... 
Protein Synthesis, Post-Translational Modification, and Degradation
Journal Article
Journal of Neural Transmission, ISSN 0300-9564, 5/2010, Volume 117, Issue 5, pp. 599 - 604
DJ-1 is a neuroprotective gene mutated in recessive Parkinson’s disease (PD). In addition to direct protective functions in neurons, DJ-1 regulates... 
Neurology | Caenorhabditis elegans | p38 MAPK pathway | Medicine & Public Health | Innate immunity | DJ-1 | Pharmacology/Toxicology | Psychiatry | Parkinson’s disease
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2007, Volume 282, Issue 18, pp. 13680 - 13691
Mutations in the PARK7 gene encoding DJ-1 cause autosomal recessive Parkinson disease. The most deleterious point mutation is the L166P substitution, which... 
Journal Article
Tübingen, Univ., Diss., 2009 
Dissertation
Welt am Sonntag, 08/2017
Badeleiter André Tabbert vom Berliner Prinzenbad uber Bademoden-Trends, Toleranz, Pedikure in der Dusche und die neu eroffnete Transgender-Umkleide In diesem... 
Transgender persons
Newspaper Article
Die Welt, 10/2019
Newspaper Article
Welt am Sonntag, 09/2019
Newspaper Article
Die Welt, 05/2018
Newspaper Article
Welt am Sonntag, 03/2018
Die scheinbar obsolete Kommunikationsmethode aus den fruhen Tagen des Internets erwies sich dann auch schnell als Erfolg: Heute bekommen 500.000 Leserinnen... 
Newspaper Article
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