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by Secrier, Maria and Li, Xiaodun and De Silva, Nadeera and Eldridge, Matthew D and Contino, Gianmarco and Bornschein, Jan and Macrae, Shona and Grehan, Nicola and O'Donovan, Maria and Miremadi, Ahmad and Yang, Tsun-Po and Bower, Lawrence and Chettouh, Hamza and Crawte, Jason and Galeano-Dalmau, Núria and Grabowska, Anna and Saunders, John and Underwood, Tim and Waddell, Nicola and Barbour, Andrew P and Nutzinger, Barbara and Achilleos, Achilleas and Edwards, Paul A. W and Lynch, Andy G and Tavaré, Simon and Fitzgerald, Rebecca C and Noorani, Ayesha and Elliott, Rachael Fels and Weaver, Jamie and Ross-Innes, Caryn and Smith, Laura and Abdullahi, Zarah and De La Rue, Rachel and Cluroe, Alison and Malhotra, Shalini and Hardwick, Richard and Ford, Hugo and Smith, Mike L and Davies, Jim and Turkington, Richard and Hayes, Stephen J and Ang, Yeng and Preston, Shaun R and Oakes, Sarah and Bagwan, Izhar and Save, Vicki and Skipworth, Richard J.E and Hupp, Ted R and O'Neill, J. Robert and Tucker, Olga and Taniere, Philippe and Noble, Fergus and Owsley, Jack and Lovat, Laurence and Haidry, Rehan and Eneh, Victor and Crichton, Charles and Barr, Hugh and Shepherd, Neil and Old, Oliver and Lagergren, Jesper and Gossage, James and Davies, Andrew and Chang, Fuju and Zylstra, Janine and Sanders, Grant and Berrisford, Richard and Harden, Catherine and Bunting, David and Lewis, Mike and Cheong, Ed and Kumar, Bhaskar and Parsons, Simon L and Soomro, Irshad and Kaye, Philip and Collier, Pamela and Igali, Laszlo and Welch, Ian and Scott, Michael and Sothi, Shamila and Suortamo, Sari and Lishman, Suzy and Beardsmore, Duncan and Francies, Hayley E and Garnett, Mathew J and Pearson, John V and Nones, Katia and Patch, Ann-Marie and Grimmond, Sean M and OCCAMS Consortium and Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium and the Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium
Nature Genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1131 - 1141
Journal Article
by Li, Jun and Woods, Susan L and Healey, Sue and Beesley, Jonathan and Chen, Xiaoqing and Lee, Jason S and Sivakumaran, Haran and Wayte, Nicci and Nones, Katia and Waterfall, Joshua J and Pearson, John and Patch, Anne-Marie and Senz, Janine and Ferreira, Manuel A and Kaurah, Pardeep and Mackenzie, Robertson and Heravi-Moussavi, Alireza and Hansford, Samantha and Lannagan, Tamsin R.M and Spurdle, Amanda B and Simpson, Peter T and da Silva, Leonard and Lakhani, Sunil R and Clouston, Andrew D and Bettington, Mark and Grimpen, Florian and Busuttil, Rita A and Di Costanzo, Natasha and Boussioutas, Alex and Jeanjean, Marie and Chong, George and Fabre, Aurélie and Olschwang, Sylviane and Faulkner, Geoffrey J and Bellos, Evangelos and Coin, Lachlan and Rioux, Kevin and Bathe, Oliver F and Wen, Xiaogang and Martin, Hilary C and Neklason, Deborah W and Davis, Sean R and Walker, Robert L and Calzone, Kathleen A and Avital, Itzhak and Heller, Theo and Koh, Christopher and Pineda, Marbin and Rudloff, Udo and Quezado, Martha and Pichurin, Pavel N and Hulick, Peter J and Weissman, Scott M and Newlin, Anna and Rubinstein, Wendy S and Sampson, Jone E and Hamman, Kelly and Goldgar, David and Poplawski, Nicola and Phillips, Kerry and Schofield, Lyn and Armstrong, Jacqueline and Kiraly-Borri, Cathy and Suthers, Graeme K and Huntsman, David G and Foulkes, William D and Carneiro, Fatima and Lindor, Noralane M and Edwards, Stacey L and French, Juliet D and Waddell, Nicola and Meltzer, Paul S and Worthley, Daniel L and Schrader, Kasmintan A and Chenevix-Trench, Georgia
The American Journal of Human Genetics, ISSN 0002-9297, 05/2016, Volume 98, Issue 5, pp. 830 - 842
Journal Article
by Oates, Emily C and Jones, Kristi J and Donkervoort, Sandra and Charlton, Amanda and Brammah, Susan and Smith, John E and Ware, James S and Yau, Kyle S and Swanson, Lindsay C and Whiffin, Nicola and Peduto, Anthony J and Bournazos, Adam and Waddell, Leigh B and Farrar, Michelle A and Sampaio, Hugo A and Teoh, Hooi Ling and Lamont, Phillipa J and Mowat, David and Fitzsimons, Robin B and Corbett, Alastair J and Ryan, Monique M and O'Grady, Gina L and Sandaradura, Sarah A and Ghaoui, Roula and Joshi, Himanshu and Marshall, Jamie L and Nolan, Melinda A and Kaur, Simranpreet and Punetha, Jaya and Töpf, Ana and Harris, Elizabeth and Bakshi, Madhura and Genetti, Casie A and Marttila, Minttu and Werlauff, Ulla and Streichenberger, Nathalie and Pestronk, Alan and Mazanti, Ingrid and Pinner, Jason R and Vuillerot, Carole and Grosmann, Carla and Camacho, Ana and Mohassel, Payam and Leach, Meganne E and Foley, A. Reghan and Bharucha‐Goebel, Diana and Collins, James and Connolly, Anne M and Gilbreath, Heather R and Iannaccone, Susan T and Castro, Diana and Cummings, Beryl B and Webster, Richard I and Lazaro, Leïla and Vissing, John and Coppens, Sandra and Deconinck, Nicolas and Luk, Ho‐Ming and Thomas, Neil H and Foulds, Nicola C and Illingworth, Marjorie A and Ellard, Sian and McLean, Catriona A and Phadke, Rahul and Ravenscroft, Gianina and Witting, Nanna and Hackman, Peter and Richard, Isabelle and Cooper, Sandra T and Kamsteeg, Erik‐Jan and Hoffman, Eric P and Bushby, Kate and Straub, Volker and Udd, Bjarne and Ferreiro, Ana and North, Kathryn N and Clarke, Nigel F and Lek, Monkol and Beggs, Alan H and Bönnemann, Carsten G and MacArthur, Daniel G and Granzier, Henk and Davis, Mark R and Laing, Nigel G
Annals of Neurology, ISSN 0364-5134, 06/2018, Volume 83, Issue 6, pp. 1105 - 1124
Journal Article
by Bailey, Peter and Chang, David K and Nones, Katia and Johns, Amber L and Patch, Ann-Marie and Gingras, Marie-Claude and Miller, David K and Christ, Angelika N and Bruxner, Tim J. C and Quinn, Michael C and Nourse, Craig and Murtaugh, L. Charles and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourbakhsh, Ehsan and Wani, Shivangi and Fink, Lynn and Holmes, Oliver and Chin, Venessa and Anderson, Matthew J and Kazakoff, Stephen and Leonard, Conrad and Newell, Felicity and Waddell, Nick and Wood, Scott and Xu, Qinying and Wilson, Peter J and Cloonan, Nicole and Kassahn, Karin S and Taylor, Darrin and Quek, Kelly and Robertson, Alan and Pantano, Lorena and Mincarelli, Laura and Sanchez, Luis N and Evers, Lisa and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Jones, Marc D and Colvin, Emily K and Nagrial, Adnan M and Humphrey, Emily S and Chantrill, Lorraine A and Mawson, Amanda and Humphris, Jeremy and Chou, Angela and Pajic, Marina and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Lovell, Jessica A and Merrett, Neil D and Toon, Christopher W and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Moran-Jones, Kim and Jamieson, Nigel B and Graham, Janet S and Duthie, Fraser and Oien, Karin and Hair, Jane and Grützmann, Robert and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Rusev, Borislav and Capelli, Paola and Salvia, Roberto and Tortora, Giampaolo and Mukhopadhyay, Debabrata and Petersen, Gloria M and Munzy, Donna M and Fisher, William E and Karim, Saadia A and Eshleman, James R and Hruban, Ralph H and Pilarsky, Christian and Morton, Jennifer P and Sansom, Owen J and Scarpa, Aldo and Musgrove, Elizabeth A and Bailey, Ulla-Maja Hagbo and Hofmann, Oliver and Sutherland, Robert L and Wheeler, David A and Gill, Anthony J and Gibbs, Richard A and Pearson, John V and Waddell, Nicola and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 47 - 52
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-beta,... 
NETWORK ANALYSIS | BREAST-CANCER | DUCTAL ADENOCARCINOMA | PACKAGE | MULTIDISCIPLINARY SCIENCES | TUMOR | MUTATIONS | DIFFERENTIATION | CELL FORMATION | RNA-SEQ DATA | EXPRESSION DATA | Pancreatic Neoplasms - metabolism | Prognosis | Hepatocyte Nuclear Factor 3-beta - genetics | Genomics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Hepatocyte Nuclear Factor 3-gamma - genetics | Gene Regulatory Networks | Histone Demethylases - genetics | Tumor Suppressor Protein p53 - genetics | Carcinoma, Pancreatic Ductal - genetics | DNA Methylation | Tumor Suppressor Proteins - genetics | Carcinoma, Pancreatic Ductal - classification | Trans-Activators - genetics | Pancreatic Neoplasms - classification | Transcription, Genetic | Nuclear Proteins - genetics | Carcinoma, Pancreatic Ductal - immunology | Genes, Neoplasm - genetics | Basic Helix-Loop-Helix Transcription Factors - genetics | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Carcinoma, Pancreatic Ductal - pathology | Genome, Human - genetics | Homeodomain Proteins - genetics | Animals | Pancreatic Neoplasms - immunology | Survival Analysis | Cell Line, Tumor | Mice | Physiological aspects | Pancreatic cancer | Methods | Genes | Genomes | Mutation | Gene expression | Tumors | Index Medicus
Journal Article
by Waddell, Nicola and Pajic, Marina and Patch, Ann-Marie and Chang, David K and Kassahn, Karin S and Bailey, Peter and Johns, Amber L and Miller, David and Nones, Katia and Quek, Kelly and Quinn, Michael C. J and Robertson, Alan J and Fadlullah, Muhammad Z. H and Bruxner, Tim J. C and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wani, Shivangi and Wilson, Peter J and Markham, Emma and Cloonan, Nicole and Anderson, Matthew J and Fink, J. Lynn and Holmes, Oliver and Kazakoff, Stephen H and Leonard, Conrad and Newell, Felicity and Poudel, Barsha and Song, Sarah and Taylor, Darrin and Waddell, Nick and Wood, Scott and Xu, Qinying and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Lee, Hong C and Jones, Marc D and Nagrial, Adnan M and Humphris, Jeremy and Chantrill, Lorraine A and Chin, Venessa and Steinmann, Angela M and Mawson, Amanda and Humphrey, Emily S and Colvin, Emily K and Chou, Angela and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Pettitt, Jessica A and Merrett, Neil D and Toon, Christopher and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Jamieson, Nigel B and Graham, Janet S and Niclou, Simone P and Bjerkvig, Rolf and Grützmann, Robert and Aust, Daniela and Hruban, Ralph H and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Falconi, Massimo and Zamboni, Giuseppe and Tortora, Giampaolo and Tempero, Margaret A and Gill, Anthony J and Eshleman, James R and Pilarsky, Christian and Scarpa, Aldo and Musgrove, Elizabeth A and Pearson, John V and Biankin, Andrew V and Grimmond, Sean M and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7540, pp. 495 - 501
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 175 - 180
Melanoma of the skin is a common cancer only in Europeans, whereas it arises in internal body surfaces (mucosal sites) and on the hands and feet (acral sites)... 
TERT PROMOTER MUTATIONS | UVEAL MELANOMA | SEQUENCE DATA | MULTIDISCIPLINARY SCIENCES | RECURRENT MUTATIONS | FREQUENT SOMATIC MUTATIONS | MALIGNANT-MELANOMA | GENERAL FRAMEWORK | CANCER GENOMES | ACTIVATING MUTATIONS | DRIVER MUTATIONS | Membrane Proteins - genetics | Humans | X-linked Nuclear Protein | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Mutation - genetics | Genes, p16 | Genome, Human - genetics | Tumor Suppressor Protein p53 - genetics | Ultraviolet Rays - adverse effects | Telomerase - genetics | Signal Transduction - drug effects | GTP Phosphohydrolases - genetics | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Mitogen-Activated Protein Kinases - genetics | Neurofibromatosis 1 - genetics | Melanoma - classification | Nuclear Proteins - genetics | DNA Helicases - genetics | Telomere - genetics | Genetic research | Genetic aspects | Genomes | Research | Melanoma | Pathogenesis | Copy number | Mucosa | p53 Protein | Radiation | Security | Epidemiology | Metastases | Reproduction (copying) | Coding | Mismatch repair | Clusters | Eye (anatomy) | Fellowships | Deoxyribonucleic acid--DNA | Medical research | Breakpoints | Radiation effects | MAP kinase | Exposure | Sun | Amplification | Bridges | Pathology | Ultraviolet radiation | Mutagenesis | Computation | Skin | Mutation | Internet | Aberration | Biotechnology | Genes | DNA damage | Carcinogens | Infrastructure | Signatures | Health | U.V. radiation | Inversions | Foldback | Data processing | Energy policy | Readers | Deamination | Protein kinase | Cell lines | Gene mapping | Tumors | Cancer | Index Medicus | Biological Science | 60 APPLIED LIFE SCIENCES
Journal Article