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PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27690
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2013, Volume 123, Issue 10, pp. 4464 - 4478
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2018, Volume 13, Issue 4, pp. e0191926 - e0191926
CTLA-4 and CD28 exemplify a co-inhibitory and co-stimulatory signaling axis that dynamically sculpts the interaction of antigen-specific T cells with... 
UNTREATED MELANOMA | CYTOKINE RELEASE ASSAYS | LUNG-CANCER | IN-VITRO | MEDIATED CYTOTOXICITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | CTLA-4 | ANTITUMOR ACTIVITIES | NIVOLUMAB PLUS IPILIMUMAB | Antineoplastic Agents, Immunological - toxicity | Epitope Mapping | Adjuvants, Immunologic - pharmacology | Antineoplastic Agents, Immunological - pharmacokinetics | Cricetulus | Cancer Vaccines - pharmacology | Humans | Immunoglobulin G - toxicity | Macaca fascicularis | Antineoplastic Agents, Immunological - chemistry | T-Lymphocytes, Regulatory - immunology | Adjuvants, Immunologic - pharmacokinetics | Neoplasms - therapy | Immunity, Cellular - drug effects | Adjuvants, Immunologic - chemistry | Immunoglobulin G - pharmacology | CHO Cells | Amino Acid Sequence | Immunoglobulin G - chemistry | Cells, Cultured | Models, Molecular | Adjuvants, Immunologic - toxicity | CTLA-4 Antigen - immunology | Antineoplastic Agents, Immunological - pharmacology | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocyte Activation - drug effects | Neoplasms - immunology | Antibody Formation - drug effects | CTLA-4 Antigen - antagonists & inhibitors | Toxicology | Pharmacology, Experimental | Research | Immunoglobulin G | Analysis | CD86 antigen | PD-1 protein | Lung cancer | Antibodies | Biochemistry | Lymphocytes T | CD28 antigen | Immunity | CTLA-4 protein | Lymphocytes | Immunotherapy | Combined vaccines | Primates | Repressing | Medical research | Immunoglobulins | Cytokines | Immunoregulation | Immunomodulation | Research & development--R&D | CD80 antigen | Pharmacology | T cell receptors | Chemical compounds | Signaling | Antigen-presenting cells | Biomarkers | Index Medicus | Research & development | R&D
Journal Article
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 58, pp. 31171 - 31172
Journal Article
OncoImmunology, ISSN 2162-4011, 07/2012, Volume 1, Issue 4, pp. 550 - 551
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2014, Volume 289, Issue 22, pp. 15642 - 15652
Tyrosine kinase inhibitors such as imatinib can effectively target the BCR-ABL oncoprotein in a majority of patients with chronic myeloid leukemia (CML).... 
CHRONIC MYELOGENOUS LEUKEMIA | STAT Transcription Factor | TYROSINE PHOSPHORYLATION | Leukemia | CONSTITUTIVE ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ABL | PERIPHERAL T-CELLS | HEMATOPOIETIC PROGENITORS | WILMS-TUMOR | Cancer Therapy | ICSBP DEFICIENCY | Cell Death | Tumor Suppressor Gene | SEQUENCE BINDING-PROTEIN | EXPRESSION | Transcription, Genetic - drug effects | Humans | Middle Aged | Interferon Regulatory Factors - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Molecular Sequence Data | Male | Gene Knockdown Techniques | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Base Sequence | Genes, Tumor Suppressor - physiology | Tumor Suppressor Proteins - genetics | Adult | Female | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Tumor Suppressor Proteins - metabolism | Gene Expression Regulation, Leukemic - drug effects | Interferon Regulatory Factors - genetics | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Gene Expression Regulation, Leukemic - physiology | Transcription, Genetic - physiology | Animals | Promoter Regions, Genetic - physiology | K562 Cells | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Aged | Mice | Gene Regulation
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2018, Volume 33, Issue 6, pp. 1033 - 1047.e5
Journal Article
Journal of Applied Ecology, ISSN 0021-8901, 12/1998, Volume 35, Issue 6, pp. 829 - 846
Journal Article
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 45, pp. 7913 - 7919
Highlights ► Further analysis of results from a trial of two pandemic vaccines was performed. ► Immune response was increased in those with post vaccination... 
Allergy and Immunology | Pandemic vaccine | Immunogenicity | Reactogenicity | Fever | Atopy | MEDICINE, RESEARCH & EXPERIMENTAL | MULTICENTER | SAFETY | TETANUS | OPEN-LABEL | IMMUNOLOGY | CHILDREN | PARALLEL-GROUP | INFECTION | ENGLAND | AGE | Influenza A Virus, H1N1 Subtype - immunology | Influenza Vaccines - administration & dosage | alpha-Tocopherol - administration & dosage | Adjuvants, Immunologic - administration & dosage | Humans | Child, Preschool | Infant | Male | Antibodies, Viral - blood | Adjuvants, Immunologic - adverse effects | Hemagglutination Inhibition Tests | Polysorbates - administration & dosage | Female | Vaccines, Subunit - adverse effects | Child | Polysorbates - adverse effects | Influenza Vaccines - adverse effects | Squalene - administration & dosage | Vaccines, Subunit - immunology | Squalene - adverse effects | Vaccines, Inactivated - adverse effects | Vaccines, Inactivated - immunology | Influenza Vaccines - immunology | Vaccines, Inactivated - administration & dosage | alpha-Tocopherol - adverse effects | Vaccines, Subunit - administration & dosage | Influenza, Human - prevention & control | Drug Combinations | Influenza, Human - immunology | Influenza vaccines | Epidemics | Immune response | Analysis | Influenza | Vaccination | Studies | Confidence intervals | Variables | Ethnicity | Clinical trials | Statistical methods | Infections | Vaccines | Gender | Age
Journal Article
Oncoimmunology, ISSN 2162-4011, 07/2012, Volume 1, Issue 4, pp. 550 - 551
Myeloid-derived suppressor cells (MDSC) induced during neoplasia display potent pro-tumorigenic activities. Tumor-derived factors influence MDSC development,... 
Immunosuppression | tumor progression | myeloid-derived suppressor Cells | Author's View | immunosurveillance | inflammation and cancer
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e14126 - e14126
e14126 Background: Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is an inhibitory receptor that modulates T cell priming and CD28-dependent T cell... 
Journal Article