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FUTURE MEDICINAL CHEMISTRY, ISSN 1756-8919, 08/2012, Volume 4, Issue 12, pp. 1537 - 1539
Loren D Walensky is an Associate Professor of Pediatrics at Harvard Medical School, faculty member in the Department of Pediatric Hematology/Oncology at... 
CHEMISTRY, MEDICINAL | Small Molecule Libraries - chemistry | Peptides - chemistry | Protein Structure, Secondary | Humans | Peptides - pharmacokinetics | Proto-Oncogene Proteins c-bcl-2 - chemistry | Small Molecule Libraries - pharmacokinetics | Peptides - therapeutic use | Neoplasms - drug therapy
Journal Article
Future Medicinal Chemistry, ISSN 1756-8919, 08/2012, Volume 4, Issue 12, pp. 1537 - 1539
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 04/2019, Volume 25, Issue 4, pp. 259 - 261
BAX is a formidable BCL-2 family protein that executes cellular suicide in response to physiologic and pathologic stress. A new article in (Garner ) reports... 
BAX | apoptosis | small molecule | BCL-2 family | inhibitor | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Cell death
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. SY37-01 - SY37-01
Journal Article
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2016, Volume 110, Issue 3, pp. 415a - 416a
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 03/2013, Volume 9, Issue 3, pp. 141 - 143
  PUMA is a BCL-2 family protein that transmits stress signals to promote apoptosis. Upon DNA damage, a unique binding determinant within PUMA triggers partial... 
APOPTOSIS | BAX | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | P53 | Proto-Oncogene Proteins - metabolism | Protein Unfolding | Humans | Tumor Suppressor Protein p53 - metabolism | bcl-X Protein - metabolism | Apoptosis | Apoptosis Regulatory Proteins - metabolism | Proteins | Biochemistry | DNA damage | Genomics | Cell cycle
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. SY06-03 - SY06-03
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2012, Volume 46, Issue 5, pp. 554 - 556
In this issue of , report that hES cells localize a conformationally activated form of proapoptotic BAX to the trans Golgi network, a previously unanticipated... 
APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Cells
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2016, Volume 110, Issue 3, p. 415
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1901 - 1901
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 2158 - 2158
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 2024 - 2024
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 3552 - 3552
The BH3-only proteins BIM, BID, and PUMA have emerged as both inhibitors of anti-apoptotic BCL-2 family proteins and direct activators of the pro-apoptotic... 
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. 3845 - 3845
The development of selective inhibitors for the individual anti-apoptotic BCL-2 family proteins implicated in oncogenesis and chemoresistance remains a... 
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 3845 - 3845
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 03/2013, Volume 9, Issue 3, pp. 141 - 143
PUMA is a BCL-2 family protein that transmits stress signals to promote apoptosis. Upon DNA damage, a unique binding determinant within PUMA triggers partial... 
Journal Article
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 12/2011, Volume 36, Issue 12, p. 642
BAX, the BCL-2-associated X protein, is a cardinal proapoptotic member of the BCL-2 family, which regulates the critical balance between cellular life and... 
Proteins | Mitochondria | Biochemistry | Cells | Apoptosis
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2954 - 2954
Journal Article
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