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chemistry, multidisciplinary (16) 16
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Dalton Transactions, ISSN 1477-9226, 2015, Volume 44, Issue 40, pp. 17482 - 17493
The ruthenium anticancer compound NAMI-A, imidazolium [trans-RuCl4(1H-imidazole)(DMSO-S)], is currently undergoing advanced clinical evaluation. As with other... 
MOLECULAR-STRUCTURE | ANTIMETASTATIC ACTIVITY | X-RAY-STRUCTURE | DOUBLE-RESONANCE | CAPILLARY-ELECTROPHORESIS | TUMOR-CELLS | DRUG CANDIDATES | EGG-WHITE LYSOZYME | BOVINE SERUM-ALBUMIN | RUTHENIUM(III) COMPLEXES | CHEMISTRY, INORGANIC & NUCLEAR | Phosphates | Alanine | Histidine | Analogue | Imidazole | Amino acids | Ligands | Diagnostic systems | Electron paramagnetic resonance
Journal Article
ISSN 1477-9226, 10/2015, Volume 44, Issue 4, pp. 17482 - 17493
The ruthenium anticancer compound NAMI-A, imidazolium [ trans -RuCl 4 (1 H -imidazole)(DMSO- S )], is currently undergoing advanced clinical evaluation. As... 
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 6, pp. 1634 - 1643
Alzheimer's disease (AD) is a multifaceted disease that is characterized by increased oxidative stress, metal-ion dysregulation, and the formation of... 
Binding | Peptides | Toxicity | Agglomeration | Weight | Constraining | Antioxidants | Histidine | Catalase | Aggregates | Electron paramagnetic resonance | Catalysis | Coordination compounds | Alzheimers disease | Alzheimer's disease
Journal Article
ISSN 1359-7345, 1/2017, Volume 53, Issue 3, pp. 651 - 654
Rapid and low overpotential oxidation of water to dioxygen remains a key hurdle for storage of solar energy. Here, we address this issue by demonstrating that... 
Journal Article
FRONTIERS IN CHEMISTRY, ISSN 2296-2646, 12/2019, Volume 7, p. 838
Alzheimer's disease (AD) is the most common form of dementia, leading to loss of cognition, and eventually death. The disease is characterized by the formation... 
peptide aggregation | RUTHENIUM METALATION | ALZHEIMERS-DISEASE | X-RAY-STRUCTURE | REACTIVITY | COPPER-BINDING | Ru(III) complexes | amyloid-beta peptide | CHEMISTRY, MULTIDISCIPLINARY | PLATINUM-BASED INHIBITORS | NAMI-A | HISTIDINE | AMYLOID-BETA | dementia | SOLUBLE OLIGOMERS | Alzheimer's disease
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 04/2012, Volume 18, Issue 14, pp. 4170 - 4173
Supporting evidence: Supported dihydrogen–metal complexes have been proposed for room‐temperature hydrogen storage, however, there has been little experimental... 
neutron scattering | dihydrogen compounds | density functional calculations | hydrogen storage | STORAGE | FRAGMENTS | ETHYLENE | MOLECULAR-HYDROGEN | COMPLEXES | ADSORPTION | CHEMISTRY, MULTIDISCIPLINARY | TI(III) IONS | Binding | Activated | Hydrogen storage | Formations | Neutron scattering | Organometallic compounds
Journal Article
Dalton transactions (Cambridge, England : 2003), ISSN 1477-9226, 10/2015, Volume 44, Issue 40, pp. 17482 - 17493
The ruthenium anticancer compound NAMI-A, imidazolium [trans-RuCl4(1H-imidazole)(DMSO-S)], is currently undergoing advanced clinical evaluation. As with other... 
Electron Spin Resonance Spectroscopy | Dimethyl Sulfoxide - chemistry | Humans | Protein Binding | Alanine - chemistry | Ligands | Organometallic Compounds - chemistry | Cysteine - chemistry | Dimethyl Sulfoxide - analogs & derivatives | Antineoplastic Agents - chemistry | Buffers | Serum Albumin - chemistry
Journal Article
ISSN 1756-5901, 11/2013, Volume 5, Issue 12, pp. 1624 - 1633
EPR (electron paramagnetic resonance) has been used to study interactions of the Ru( iii ) anticancer compounds imidazolium [ trans -RuCl 4 (1 H... 
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 05/2016, Volume 55, Issue 10, pp. 4850 - 4863
Journal Article
European Journal of Inorganic Chemistry, ISSN 1434-1948, 03/2017, Volume 2017, Issue 12, pp. 1573 - 1585
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 01/2017, Volume 53, Issue 3, pp. 651 - 654
Rapid and low overpotential oxidation of water to dioxygen remains a key hurdle for storage of solar energy. Here, we address this issue by demonstrating that... 
Catalysts | Imidazole | Solar energy | Ligands | Oxidation | Copper | Speciation | Bearing
Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 53, Issue 3, pp. 651 - 654
Rapid and low overpotential oxidation of water to dioxygen remains a key hurdle for storage of solar energy. Here, we address this issue by demonstrating that... 
CATALYSIS | HYDROGEN-ATOM TRANSFER | COMPLEXES | PHOTOSYSTEM-II | HYDROLYSIS | REACTIVITY | RUTHENIUM | ELECTROCATALYST | RIESKE CLUSTERS | CHEMISTRY, MULTIDISCIPLINARY | PROTONATION
Journal Article
Journal Article
ISSN 1477-9226, 11/2016, Volume 45, Issue 45, pp. 1879 - 1883
A Ru( ii ) arene complex with a NO-releasing 4-nitrooxymethyl-pyridine ligand shows increased cytotoxicity against the non-small cell lung cancer cell line... 
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 12/2013, Volume 19, Issue 50, pp. 17031 - 17042
A series of pyridine‐based derivatives of the clinically successful RuIII‐based complexes indazolium [trans‐RuCl4(1 H‐indazole)2] (KP1019) and sodium... 
ligand design | ruthenium | hydrophobic interactions | cytotoxicity | albumin | Albumin | Care and treatment | Ruthenium | Colon cancer | Pyridine | Cancer | Proteins | Berries | Cytotoxicity
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 04/2018, Volume 24, Issue 24, pp. 6334 - 6338
Low aqueous solubility is a major barrier to the clinical application of otherwise promising drug candidates. We demonstrate that this issue can be resolved in... 
bioinorganic | copper | cancer | nuclear magnetic resonance | zinc | Chemotherapy | RNA | Transition metal compounds | Cancer | Incubation | Toxicity | Cytotoxicity | Bioavailability | Hydrophobicity | Solubilization | Drug development | pH effects | DNA-directed RNA polymerase | Zinc | Polymerase | Ribonucleic acids | Pyrazine | Computer applications | Copper | Metal ions
Journal Article