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Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A14009 - A14009
IntroductionIn observational studies, major circulating lipids (e.g. low density lipoprotein cholesterol) are associated with risk of myocardial infarction... 
Journal Article
by Jacquemont, S and Reymond, A and Zufferey, F and Harewood, L and Walters, R.G and Kutalik, Z and Martinet, D and Shen, Y and Valsesia, A and Beckmann, N.D and Thorleifsson, G and Belfiore, M and Bouquillon, S and Campion, D and Leeuw, N. de and Vries, L.B.A. de and Esko, T and Fernandez, B.A and Fernandez-Aranda, F and Fernandez-Real, J.M and Gratacos, M and Guilmatre, A and Hoyer, J and Jarvelin, M.R and Kooy, R.F and Kurg, A and Caignec, C. Le and Mannik, K and Platt, O.S and Sanlaville, D and Haelst, M.M. van and Villatoro Gomez, S and Walha, F and Wu, B.L and Yu, Y and Aboura, A and Addor, M.C and Alembik, Y and Antonarakis, S.E and Arveiler, B and Barth, M and Bednarek, N and Bena, F and Bergmann, S and Beri, M and Bernardini, L and Blaumeiser, B and Bonneau, D and Bottani, A and Boute, O and Brunner, H.G and Cailley, D and Callier, P and Chiesa, J and Chrast, J and Coin, L and Coutton, C and Cuisset, J.M and Cuvellier, J.C and David, A and Freminville, B. de and Delobel, B and Delrue, M.A and Demeer, B and Descamps, D and Didelot, G and Dieterich, K and Disciglio, V and Doco-Fenzy, M and nat, S and Duban-Bedu, B and Dubourg, C and El-Sayed Moustafa, J.S and Elliott, P and Faas, B.H.W and Faivre, L and Faudet, A and Fellmann, F and Ferrarini, A and Fisher, R and Flori, E and Forer, L and Gaillard, D and Gerard, M and Gieger, C and Gimelli, S and Gimelli, G and Grabe, H.J and Guichet, A and Guillin, O and Hartikainen, A.L and Heron, D and Hippolyte, L and Holder, M and Homuth, G and Isidor, B and Jaillard, S and Jaros, Z and Jimenez-Murcia, S and Helas, G.J and ...
Nature, ISSN 0028-0836, 2011, Volume 478, Issue 7367, pp. 97 - 102
Both obesity and being underweight have been associated with increased mortality. Underweight, defined as a body mass index (BMI) DEPENDENT PROBE AMPLIFICATION | FAILURE-TO-THRIVE | METABOLIC SYNDROME | RELATIVE QUANTIFICATION | SNP GENOTYPING DATA | HIDDEN-MARKOV MODEL | MULTIDISCIPLINARY SCIENCES | BODY-MASS INDEX | TIME QUANTITATIVE PCR | COPY NUMBER VARIATION | CIRCULAR BINARY SEGMENTATION | Humans | Middle Aged | Child, Preschool | RNA, Messenger - analysis | Head - anatomy & histology | Infant | Male | Developmental Disabilities - genetics | Gene Expression Profiling | North America | Obesity - genetics | Case-Control Studies | Young Adult | Mental Disorders - genetics | Aging | Gene Duplication - genetics | Adult | Female | Transcription, Genetic | Energy Metabolism - genetics | Child | Infant, Newborn | Chromosomes, Human, Pair 16 - genetics | Body Mass Index | Gene Dosage - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Europe | RNA, Messenger - genetics | Mutation - genetics | Body Height - genetics | Thinness - genetics | Phenotype | Comparative Genomic Hybridization | Adolescent | Heterozygote | Aged | Cohort Studies | Sequence Deletion - genetics | Obesity | Chromosome mapping | Usage | Genetic variation | Genetic aspects | Cognition disorders | Research | Risk factors | Schizophrenia | Gender | Behavior | Gene expression | Bias | Index Medicus | Life Sciences | Human health and pathology | Genetics | Endocrinology and metabolism | Gene Duplication | Developmental Disabilities | Sequence Deletion | Thinness | genetics | Genetic Predisposition to Disease | Head | Gene Dosage | analysis | Energy Metabolism | Mental Disorders | Chromosomes, Human, Pair 16 | Body Height | Mutation | anatomy & histology | RNA, Messenger
Journal Article
by Wain, Louise V and Shrine, Nick R. G and Artigas, Maria Soler and Erzurumluoglu, A Mesut and Noyvert, Boris and Bossini-Castillo, Lara and Obeidat, Ma'en and Henrys, Amanda P and Portelli, Michael A and Hall, Robert J and Billington, Charlotte K and Rimington, Tracy L and Fenech, Anthony G and John, Catherine and Blake, Tineka and Jackson, Victoria E and Allen, Richard J and Prins, Bram P and Campbell, Archie and Porteous, David J and Jarvelin, Marjo-Riitta and Wielscher, Matthias and Jamess, Alan L and Hui, Jennie and Wareham, Nicholas J and Zhao, Jing Hua and Wilson, James F and Joshi, Peter K and Stubbe, Beate and Rawal, Rajesh and Schulz, Holger and Imboden, Medea and Probst-Hensch, Nicole M and Karrasch, Stefan and Gieger, Christian and Deary, Ian J and Harris, Sarah E and Marten, Jonathan and Rudan, Igor and Enroth, Stefan and Gyllensten, Ulf and Kerr, Shona M and Polasek, Ozren and Kahonen, Mika and Surakka, Ida and Vitart, Veronique and Hayward, Caroline and Lehtimaki, Terho and Raitakari, Olli T and Evans, David M and Henderson, A. John and Pennell, Craig E and Wang, Carol A and Sly, Peter D and Wan, Emily S and Busch, Robert and Hobbs, Brian D and Litonjua, Augusto and Sparrow, David W and Gulsvik, Amund and Bakke, Per S and Crapo, James D and Beaty, Terri H and Hansel, Nadia N and Mathias, Rasika A and Ruczinski, Ingo and Barnes, Kathleen C and Bosse, Yohan and Joubert, Philippe and van den Berge, Maarten and Brandsma, Corry-Anke and Pare, Peter D and Sin, Don and Nickle, David C and Hao, Ke and Gottesman, Omri and Dewey, Frederick E and Bruse, Shannon E and Carey, David J and Kirchner, H Lester and Jonsson, Stefan and Thorleifsson, Gudmar and Jonsdottir, Ingileif and Gislason, Thorarinn and Stefansson, Kari and Schurmann, Claudia and Nadkarni, Girish N and Bottinger, Erwin P and Loos, Ruth J. F and Walters, Robin G and Chen, Zhengming and Millwood, Iona Y and Vaucher, Julien and Kurmi, Om P and Li, Liming and Hansell, Anna L and Brightling, Chris and Zeggini, Eleftheria and Cho, Michael H and Silverman, Edwin K and ... and Geisinger-Regeneron DiscovEHR and Understanding Soc Sci Grp and Understanding Society Scientific Group and Geisinger-Regeneron DiscovEHR Collaboration and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 03/2017, Volume 49, Issue 3, pp. 416 - 425
Journal Article
PLoS Medicine, ISSN 1549-1277, 05/2018, Volume 15, Issue 5, pp. e1002566 - e1002566
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 09/2009, Volume 18, Issue 17, pp. 3257 - 3265
Journal Article
The Lancet, ISSN 0140-6736, 05/2019, Volume 393, Issue 10183, pp. 1831 - 1842
Moderate alcohol intake has been associated with reduced cardiovascular risk in many studies, in comparison with abstinence or with heavier drinking. Studies... 
0.5 MILLION PEOPLE | STROKE | MORTALITY | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | VARIANTS | RISK | CORONARY-HEART-DISEASE | ASSOCIATION | BLOOD-PRESSURE | CONSUMPTION | Alcohol Dehydrogenase - metabolism | Cardiovascular Diseases - etiology | Myocardial Infarction - epidemiology | Prospective Studies | Humans | Middle Aged | Far East - epidemiology | Aldehyde Dehydrogenase, Mitochondrial - metabolism | Genotype | Male | China - epidemiology | Alcohol Drinking - adverse effects | Cardiovascular Diseases - genetics | Alcohol Drinking - genetics | Incidence | Cerebral Hemorrhage - epidemiology | Alcohol Drinking - epidemiology | Cardiovascular Diseases - epidemiology | Adult | Female | Stroke - epidemiology | Aged | Blood Pressure - physiology | Genetic research | Medicine, Experimental | Blood circulation disorders | Medical research | Drinking of alcoholic beverages | Analysis | Myocardial infarction | Spirits | Alcohol | Cardiovascular disease | Alcohol dehydrogenase | Epidemiology | Hemorrhage | Aldehyde dehydrogenase | Risk factors | Alcohol use | Vascular diseases | Risk assessment | Blood pressure | Beverages | Genotypes | Predictive control | Women | Cerebral infarction | Stroke | Drinking behavior | Health risks | Drinking | Metabolism | Disease control | Morbidity | Studies | Genetic variance | Men | Alcoholic beverages | Alcoholic drinks | Recording | Cardiovascular diseases | Health risk assessment | Index Medicus | Abridged Index Medicus
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2018, Volume 71, Issue 6, pp. 620 - 632
Blood lipids are established risk factors for myocardial infarction (MI), but uncertainty persists about the relevance of lipids, lipoprotein particles, and... 
intracerebral hemorrhage | epidemiology | metabolomics | ischemic stroke | myocardial infarction | etiology | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | RANDOMIZED-TRIALS | VASCULAR-DISEASE | LDL CHOLESTEROL | MAGNETIC-RESONANCE METABOLOMICS | HEART-DISEASE | ACUTE-PHASE GLYCOPROTEINS | GENOME-WIDE | CORONARY-ARTERY-DISEASE | GLYCA | Blood lipids | Metabolites | Heart attack | Risk factors | Myocardial infarction | Nuclear magnetic resonance--NMR | Lipids | Cardiovascular disease | Ketone bodies | Docosahexaenoic acid | Hemorrhage | Magnetic resonance spectroscopy | Ischemia | Lipid metabolism | Lipoproteins (high density) | Cerebral infarction | Stroke | Markers | Glycoprotein | Particulates | Triglycerides | Risk analysis | Low density lipoprotein | Cholesterol | Lipoproteins | Infarction | Health risk assessment | Index Medicus | Abridged Index Medicus | HDL-C, high-density lipoprotein cholesterol | IS, ischemic stroke | LDL-C, low-density lipoprotein cholesterol | PCI, percutaneous coronary intervention | CI, confidence interval | CVD, cardiovascular disease | IHD, ischemic heart disease | CKB, China Kadoorie Biobank | IDL, intermediate-density lipoprotein | SBP, systolic blood pressure | MI, myocardial infarction | CABG, coronary artery bypass grafting | BMI, body mass index | TG, triglycerides | NMR, nuclear magnetic resonance | VLDL, very low-density lipoprotein | RCT, randomized controlled trial | CHD, coronary heart disease
Journal Article
by Sun, Luanluan and Clarke, Robert and Bennett, Derrick and Guo, Yu and Walters, Robin G and Hill, Michael and Parish, Sarah and Millwood, Iona Y and Bian, Zheng and Chen, Yiping and Yu, Canqing and Lv, Jun and Collins, Rory and Chen, Junshi and Peto, Richard and Li, Liming and Chen, Zhengming and Chen, Junshi and Chen, Zhengming and Clarke, Robert and Collins, Rory and Guo, Yu and Li, Liming and Lv, Jun and Peto, Richard and Walters, Robin and Avery, Daniel and Bennett, Derrick and Boxall, Ruth and Bragg, Fiona and Chang, Yumei and Chen, Yiping and Chen, Zhengming and Clarke, Robert and Du, Huaidong and Gilbert, Simon and Hacker, Alex and Holmes, Michael and Kartsonaki, Christiana and Kerosi, Rene and Lancaster, Garry and Lin, Kuang and McDonnell, John and Millwood, Iona and Nie, Qunhua and Radhakrishnan, Jayakrishnan and Ryder, Paul and Sansome, Sam and Schmidt, Dan and Sohoni, Rajani and Turnbull, Iain and Walters, Robin and Wang, Jenny and Wang, Lin and Wright, Neil and Yang, Ling and Yang, Xiaoming and Bian, Zheng and Guo, Yu and Han, Xiao and Hou, Can and Jing, Biao and Liu, Chao and Lv, Jun and Pei, Pei and Tan, Yunlong and Yu, Canqing and Pang, Zengchang and Gao, Ruqin and Li, Shanpeng and Wang, Shaojie and Liu, Yongmei and Du, Ranran and Zang, Yajing and Cheng, Liang and Tian, Xiaocao and Zhang, Hua and Zhai, Yaoming and Ning, Feng and Sun, Xiaohui and Li, Feifei and Lv, Silu and Wang, Junzheng and Hou, Wei and Zeng, Mingyuan and Jiang, Ge and Zhou, Xue and Yang, Liqiu and He, Hui and Yu, Bo and Li, Yanjie and Xu, Qinai and Kang, Quan and Guo, Ziyan and Wang, Dan and Hu, Ximin and Wang, Hongmei and Chen, Jinyan and Fu, Yan and Fu, Zhenwang and ... and China Kadoorie Biobank and China Kadoorie Biobank Collaborative Group and National Co-ordinating Centre, Beijing and Regional Co-ordinating Centres and International Steering Committee and International Co-ordinating Centre, Oxford and on behalf of the China Kadoorie Biobank Collaborative Group
Nature Medicine, ISSN 1078-8956, 2019, Volume 25, Issue 4, pp. 569 - 569
Journal Article