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Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 2669 - 2669
Cancer cells reprogram their metabolism to meet their energetic and biosynthetic needs, with many cancer cells showing increased aerobic glycolysis and... 
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7517, pp. 251 - 255
Journal Article
Cancer Cell, ISSN 1535-6108, 11/2012, Volume 22, Issue 5, pp. 631 - 644
Journal Article
Cancer Research, ISSN 0008-5472, 07/2012, Volume 72, Issue 14 Supplement, pp. A88 - A88
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2011, Volume 17, Issue 7, pp. 875 - 882
Cells that are deficient in homologous recombination, such as those that lack functional breast cancer-associated 1 (BRCA1) or BRCA2, are hypersensitive to... 
MEDICINE, RESEARCH & EXPERIMENTAL | POLY(ADP-RIBOSE) POLYMERASE | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | TUMORS | LINES | CELL BIOLOGY | LUNG-CANCER | REPAIR | CISPLATIN | CELL-CYCLE | HOMOLOGOUS RECOMBINATION | Neoplasm Transplantation | Phosphorylation | Humans | Male | Breast Neoplasms - physiopathology | Breast Neoplasms - metabolism | CDC2 Protein Kinase - metabolism | DNA Damage - physiology | BRCA1 Protein - metabolism | Female | Indoles - pharmacology | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - physiology | Neoplasms, Experimental - physiopathology | CDC2 Protein Kinase - physiology | Carrier Proteins - physiology | DNA Damage - drug effects | CDC2 Protein Kinase - antagonists & inhibitors | BRCA1 Protein - physiology | Nuclear Proteins - metabolism | Breast Neoplasms - drug therapy | Poly(ADP-ribose) Polymerase Inhibitors | Blotting, Western | Indazoles - pharmacology | Animals | Carrier Proteins - metabolism | Cell Line, Tumor | Benzimidazoles - pharmacology | Mice | Nuclear Proteins - physiology | Neoplasms, Experimental - metabolism | Physiological aspects | Cellular proteins | Research | Phosphotransferases | Breast cancer | Genetic recombination | DNA repair | Cyclin-dependent kinases | Tumors | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2015, Volume 22, Issue 6, pp. 1009 - 1019
The oncogene encodes MYC, a transcription factor that binds the genome through sites termed E-boxes (5′-CACGTG-3′), which are identical to the binding sites of... 
GENE | COPY NUMBER | TRANSCRIPTION | ENDOCRINOLOGY & METABOLISM | N-MYC | C-MYC | REV-ERB-ALPHA | NEUROBLASTOMA | OVARIAN-CANCER | DIFFERENTIATION | EXPRESSION | CELL BIOLOGY | Humans | CLOCK Proteins - chemistry | Glutamine - metabolism | CLOCK Proteins - genetics | RNA, Messenger - metabolism | Nuclear Receptor Subfamily 1, Group D, Member 1 - antagonists & inhibitors | Repressor Proteins - antagonists & inhibitors | CLOCK Proteins - metabolism | Period Circadian Proteins - genetics | RNA Interference | Base Sequence | Binding Sites | Dimerization | Nuclear Receptor Subfamily 1, Group D, Member 1 - metabolism | Genes, Reporter | Repressor Proteins - metabolism | Promoter Regions, Genetic | ARNTL Transcription Factors - genetics | Nuclear Receptor Subfamily 1, Group D, Member 1 - genetics | ARNTL Transcription Factors - metabolism | Repressor Proteins - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Circadian Rhythm | Proto-Oncogene Proteins c-myc - metabolism | Period Circadian Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | ARNTL Transcription Factors - chemistry | Cell Line, Tumor | Glucose - metabolism | Proto-Oncogene Proteins c-myc - genetics | RNA, Small Interfering - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Glucose metabolism | Medical colleges | Genomics | Cancer cells | Physiological aspects | Glucose | Dextrose | Cancer | Resveratrol | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 17, Issue 6, pp. 547 - 559
In mice, deletion and activation of results in lung tumors with a high penetrance of lymph node and distant metastases. We analyzed these primary and... 
CELLCYCLE | SIGNALING | EPITHELIAL-MESENCHYMAL TRANSITION | ONCOGENIC K-RAS | CANCER-CELLS | SUPPRESSOR | GENE | ONCOLOGY | SRC | KINASE INHIBITOR | EXPRESSION PROFILES | MUTATIONS | TUMORIGENESIS | Lung Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - deficiency | Protein-Tyrosine Kinases - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Genomics | Humans | Lung Neoplasms - metabolism | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Cell Movement - genetics | Phosphorylation - genetics | RNA Interference | Gene Expression Regulation, Neoplastic - genetics | MAP Kinase Kinase 1 - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - metabolism | Signal Transduction - genetics | Enzyme Inhibitors - therapeutic use | Focal Adhesion Protein-Tyrosine Kinases - antagonists & inhibitors | Focal Adhesion Protein-Tyrosine Kinases - genetics | Focal Adhesions - genetics | Signal Transduction - drug effects | Mice, Nude | Cell Line, Tumor | Mice | TOR Serine-Threonine Kinases | src-Family Kinases - genetics | Protein-Tyrosine Kinases - antagonists & inhibitors | ras Proteins - genetics | Lung Neoplasms - pathology | Cell Transdifferentiation - genetics | Protein-Tyrosine Kinases - genetics | Neoplasm Metastasis - drug therapy | Mice, Mutant Strains | Protein-Serine-Threonine Kinases - antagonists & inhibitors | src-Family Kinases - metabolism | Female | Drug Therapy, Combination | Lung Neoplasms - genetics | Cell Adhesion - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Focal Adhesion Protein-Tyrosine Kinases - metabolism | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | src-Family Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Up-Regulation - genetics | Xenograft Model Antitumor Assays | Neoplasm Metastasis - genetics | Animals | MAP Kinase Kinase 2 - antagonists & inhibitors | Protein Kinase Inhibitors - therapeutic use | Focal Adhesions - metabolism | Proteomics | Protein Kinase Inhibitors - pharmacology | Oncology, Experimental | Analysis | Lung cancer | Development and progression | Metastasis | Research | Cancer | Index Medicus
Journal Article