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Journal of biopharmaceutical statistics, ISSN 1054-3406, 07/2019, pp. 1 - 11
The traditional rule-based design, 3 + 3, has been shown to be less likely to achieve the objectives of dose-finding trials when compared with model-based... 
Journal Article
Journal of Biopharmaceutical Statistics, ISSN 1054-3406, 07/2019, Volume 29, Issue 4, pp. 722 - 727
Journal Article
Statistics in Medicine, ISSN 0277-6715, 02/2016, Volume 35, Issue 3, pp. 348 - 349
Journal Article
Journal of Biopharmaceutical Statistics, ISSN 1054-3406, 07/2019, Volume 29, Issue 4, pp. 722 - 727
While 2-in-1 designs give a flexibility to make a clinical trial either an information generation Phase 2 trial or a full scale confirmatory Phase 3 trial,... 
clinical trial | efficiency | power | Sample size | adaptive design | SEQUENTIAL DESIGN | CONFIDENCE-INTERVALS | CLINICAL-TRIALS | SAMPLE-SIZE REESTIMATION | PHARMACOLOGY & PHARMACY | STATISTICS & PROBABILITY
Journal Article
Journal of biopharmaceutical statistics, 06/2019, p. 1
While 2-in-1 designs give a flexibility to make a clinical trial either an information generation Phase 2 trial or a full scale confirmatory Phase 3 trial,... 
Journal Article
Contemporary Clinical Trials, ISSN 1551-7144, 2015, Volume 45, Issue Pt B, pp. 426 - 434
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Statistics in Biosciences, ISSN 1867-1764, 08/2018, Volume 10, Issue 2, pp. 460 - 472
Journal Article
Statistics in Biopharmaceutical Research, ISSN 1946-6315, 07/2019, Volume 11, Issue 3, pp. 239 - 251
Polycystic kidney disease is a genetic disorder that causes cysts to grow in the kidney. It is slowly progressing and often leads to end-stage kidney disease,... 
Enrichment | Biomarker | Chronic kidney disease | STATISTICS & PROBABILITY | MATHEMATICAL & COMPUTATIONAL BIOLOGY
Journal Article
Translational Cancer Research, ISSN 2218-676X, 06/2014, Volume 3, Issue 3, pp. 279 - 292
Predictive biomarkers are used to develop (binary) classifiers to identify patients as either good or poor candidates for clinical decision to optimize... 
Adaptive signature design (ASD) | Subgroup analysis | Subgroup identification | Predictive classifier | Personalized medicine | Classification | ONCOLOGY | subgroup analysis | predictive classifier | classification | personalized medicine | subgroup identification
Journal Article
Journal of Biopharmaceutical Statistics, ISSN 1054-3406, 03/2016, Volume 26, Issue 2, pp. 405 - 405
Journal Article
Biometrical Journal, ISSN 0323-3847, 05/2013, Volume 55, Issue 3, pp. 271 - 274
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63431
Journal Article
by Shi, Leming and Campbell, Gregory and Jones, Wendell D and Campagne, Fabien and Wen, Zhining and Walker, Stephen J and Su, Zhenqiang and Chu, Tzu-Ming and Goodsaid, Federico M and Pusztai, Lajos and Shaughnessy, John D and Oberthuer, André and Thomas, Russell S and Paules, Richard S and Fielden, Mark and Barlogie, Bart and Chen, Weijie and Du, Pan and Fischer, Matthias and Furlanello, Cesare and Gallas, Brandon D and Ge, Xijin and Megherbi, Dalila B and Symmans, W Fraser and Wang, May D and Zhang, John and Bitter, Hans and Brors, Benedikt and Bushel, Pierre R and Bylesjo, Max and Chen, Minjun and Cheng, Jie and Cheng, Jing and Chou, Jeff and Davison, Timothy S and Delorenzi, Mauro and Deng, Youping and Devanarayan, Viswanath and Dix, David J and Dopazo, Joaquin and Dorff, Kevin C and Elloumi, Fathi and Fan, Jianqing and Fan, Shicai and Fan, Xiaohui and Fang, Hong and Gonzaludo, Nina and Hess, Kenneth R and Hong, Huixiao and Huan, Jun and Irizarry, Rafael A and Judson, Richard and Juraeva, Dilafruz and Lababidi, Samir and Lambert, Christophe G and Li, Li and Li, Yanen and Li, Zhen and Lin, Simon M and Liu, Guozhen and Lobenhofer, Edward K and Luo, Jun and Luo, Wen and McCall, Matthew N and Nikolsky, Yuri and Pennello, Gene A and Perkins, Roger G and Philip, Reena and Popovici, Vlad and Price, Nathan D and Qian, Feng and Scherer, Andreas and Shi, Tieliu and Shi, Weiwei and Sung, Jaeyun and Thierry-Mieg, Danielle and Thierry-Mieg, Jean and Thodima, Venkata and Trygg, Johan and Vishnuvajjala, Lakshmi and Wang, Sue Jane and Wu, Jianping and Wu, Yichao and Xie, Qian and Yousef, Waleed A and Zhang, Liang and Zhang, Xuegong and Zhong, Sheng and Zhou, Yiming and Zhu, Sheng and Arasappan, Dhivya and Bao, Wenjun and Lucas, Anne Bergstrom and Berthold, Frank and Brennan, Richard J and Buness, Andreas and Catalano, Jennifer G and Chang, Chang and Chen, Rong and Cheng, Yiyu and ... and MAQC Consortium and Umeå universitet and Teknisk-naturvetenskapliga fakulteten and Kemiska institutionen
Nature Biotechnology, ISSN 1087-0156, 08/2010, Volume 28, Issue 8, pp. 827 - 838
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Biometrical Journal, ISSN 0323-3847, 01/2016, Volume 58, Issue 1, pp. 133 - 153
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Statistics in Biosciences, ISSN 1867-1764, 6/2016, Volume 8, Issue 1, pp. 129 - 158
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Biometrical Journal, ISSN 0323-3847, 05/2013, Volume 55, Issue 3, pp. 275 - 293
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Journal of Virology, ISSN 0022-538X, 11/2019
The strongest evidence of the oncogenicity of Epstein-Barr virus (EBV) in vitro is its ability to immortalize human primary B lymphocytes into lymphoblastoid... 
Journal Article
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