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by Lek, Monkol and Karczewski, Konrad J and Minikel, Eric V and Samocha, Kaitlin E and Banks, Eric and Fennell, Timothy and O’Donnell-Luria, Anne H and Ware, James S and Hill, Andrew J and Cummings, Beryl B and Tukiainen, Taru and Birnbaum, Daniel P and Kosmicki, Jack A and Duncan, Laramie E and Estrada, Karol and Zhao, Fengmei and Zou, James and Pierce-Hoffman, Emma and Berghout, Joanne and Cooper, David N and Deflaux, Nicole and DePristo, Mark and Do, Ron and Flannick, Jason and Fromer, Menachem and Gauthier, Laura and Goldstein, Jackie and Gupta, Namrata and Howrigan, Daniel and Kiezun, Adam and Kurki, Mitja I and Moonshine, Ami Levy and Natarajan, Pradeep and Orozco, Lorena and Peloso, Gina M and Poplin, Ryan and Rivas, Manuel A and Ruano-Rubio, Valentin and Rose, Samuel A and Ruderfer, Douglas M and Shakir, Khalid and Stenson, Peter D and Stevens, Christine and Thomas, Brett P and Tiao, Grace and Tusie-Luna, Maria T and Weisburd, Ben and Won, Hong-Hee and Yu, Dongmei and Altshuler, David M and Ardissino, Diego and Boehnke, Michael and Danesh, John and Donnelly, Stacey and Elosua, Roberto and Florez, Jose C and Gabriel, Stacey B and Getz, Gad and Glatt, Stephen J and Hultman, Christina M and Kathiresan, Sekar and Laakso, Markku and McCarroll, Steven and McCarthy, Mark I and McGovern, Dermot and McPherson, Ruth and Neale, Benjamin M and Palotie, Aarno and Purcell, Shaun M and Saleheen, Danish and Scharf, Jeremiah M and Sklar, Pamela and Sullivan, Patrick F and Tuomilehto, Jaakko and Tsuang, Ming T and Watkins, Hugh C and Wilson, James G and Daly, Mark J and MacArthur, Daniel G and Exome Aggregation Consortium
Nature (London), ISSN 1476-4687, 2016, Volume 536, Issue 7616, pp. 285 - 291
...]; Anne H. ODonnell-Luria [1, 2, 7]; James S. Ware [2, 8, 9, 10, 11]; Andrew J. Hill [1, 2, 12]; Beryl B. Cummings [1, 2, 5]; Taru Tukiainen [1, 2]; Daniel P... 
HUMAN-DISEASE | EVOLUTION | MULTIDISCIPLINARY SCIENCES | MUTATION | GUIDELINES | FRAMEWORK | SEQUENCE VARIANTS | NETWORKS | DISCOVERY | HUMAN-POPULATION HISTORY | Genetic aspects | Research | Man | Human beings | Genetic variation | Analysis | Datasets | Proteins | Databases | Disease | Genes | Principal components analysis | Genetics | Genomes
Journal Article
by Direk, Nese and Williams, Stephanie and Smith, Jennifer A and Ripke, Stephan and Air, Tracy and Amare, Azmeraw T and Amin, Najaf and Baune, Bernhard T and Bennett, David A and Blackwood, Douglas H.R and Boomsma, Dorret and Breen, Gerome and Buttenschøn, Henriette N and Byrne, Enda M and Børglum, Anders D and Castelao, Enrique and Cichon, Sven and Clarke, Toni-Kim and Cornelis, Marilyn C and Dannlowski, Udo and De Jager, Philip L and Demirkan, Ayse and Domenici, Enrico and van Duijn, Cornelia M and Dunn, Erin C and Eriksson, Johan G and Esko, Tonu and Faul, Jessica D and Ferrucci, Luigi and Fornage, Myriam and de Geus, Eco and Gill, Michael and Gordon, Scott D and Grabe, Hans Jörgen and van Grootheest, Gerard and Hamilton, Steven P and Hartman, Catharina A and Heath, Andrew C and Hek, Karin and Hofman, Albert and Homuth, Georg and Horn, Carsten and Jan Hottenga, Jouke and Kardia, Sharon L.R and Kloiber, Stefan and Koenen, Karestan and Kutalik, Zoltán and Ladwig, Karl-Heinz and Lahti, Jari and Levinson, Douglas F and Lewis, Cathryn M and Lewis, Glyn and Li, Qingqin S and Llewellyn, David J and Lucae, Susanne and Lunetta, Kathryn L and MacIntyre, Donald J and Madden, Pamela and Martin, Nicholas G and McIntosh, Andrew M and Metspalu, Andres and Milaneschi, Yuri and Montgomery, Grant W and Mors, Ole and Mosley, Thomas H and Murabito, Joanne M and Müller-Myhsok, Bertram and Nöthen, Markus M and Nyholt, Dale R and O’Donovan, Michael C and Penninx, Brenda W and Pergadia, Michele L and Perlis, Roy and Potash, James B and Preisig, Martin and Purcell, Shaun M and Quiroz, Jorge A and Räikkönen, Katri and Rice, John P and Rietschel, Marcella and Rivera, Margarita and Schulze, Thomas G and Shi, Jianxin and Shyn, Stanley and Sinnamon, Grant C and Smit, Johannes H and Smoller, Jordan W and Snieder, Harold and Tanaka, Toshiko and Tansey, Katherine E and Teumer, Alexander and Uher, Rudolf and Umbricht, Daniel and Van der Auwera, Sandra and Ware, Erin B and Weir, David R and Weissman, Myrna M and Willemsen, Gonneke and Yang, Jingyun and Zhao, Wei and ...
Biological psychiatry (1969), ISSN 0006-3223, 09/2017, Volume 82, Issue 5, pp. 322 - 329
Journal Article
by Davies, Gail and Lam, Max and Harris, Sarah E and Trampush, Joey W and Luciano, Michelle and Hill, W. David and Hagenaars, Saskia P and Ritchie, Stuart J and Marioni, Riccardo E and Fawns-Ritchie, Chloe and Liewald, David C. M and Okely, Judith A and Ahola-Olli, Ari V and Barnes, Catriona L. K and Bertram, Lars and Bis, Joshua C and Burdick, Katherine E and Christoforou, Andrea and DeRosse, Pamela and Djurovic, Srdjan and Espeseth, Thomas and Giakoumaki, Stella and Giddaluru, Sudheer and Gustavson, Daniel E and Hayward, Caroline and Hofer, Edith and Ikram, M. Arfan and Karlsson, Robert and Knowles, Emma and Lahti, Jari and Leber, Markus and Li, Shuo and Mather, Karen A and Melle, Ingrid and Morris, Derek and Oldmeadow, Christopher and Palviainen, Teemu and Payton, Antony and Pazoki, Raha and Petrovic, Katja and Reynolds, Chandra A and Sargurupremraj, Muralidharan and Scholz, Markus and Smith, Jennifer A and Smith, Albert V and Terzikhan, Natalie and Thalamuthu, Anbupalam and Trompet, Stella and van der Lee, Sven J and Ware, Erin B and Windham, B. Gwen and Wright, Margaret J and Yang, Jingyun and Yu, Jin and Ames, David and Amin, Najaf and Amouyel, Philippe and Andreassen, Ole A and Armstrong, Nicola J and Assareh, Amelia A and Attia, John R and Attix, Deborah and Avramopoulos, Dimitrios and Bennett, David A and Böhmer, Anne C and Boyle, Patricia A and Brodaty, Henry and Campbell, Harry and Cannon, Tyrone D and Cirulli, Elizabeth T and Congdon, Eliza and Conley, Emily Drabant and Corley, Janie and Cox, Simon R and Dale, Anders M and Dehghan, Abbas and Dick, Danielle and Dickinson, Dwight and Eriksson, Johan G and Evangelou, Evangelos and Faul, Jessica D and Ford, Ian and Freimer, Nelson A and Gao, He and Giegling, Ina and Gillespie, Nathan A and Gordon, Scott D and Gottesman, Rebecca F and Griswold, Michael E and Gudnason, Vilmundur and Harris, Tamara B and Hartmann, Annette M and Hatzimanolis, Alex and Heiss, Gerardo and Holliday, Elizabeth G and Joshi, Peter K and Kähönen, Mika and Kardia, Sharon L. R and Karlsson, Ida and Kleineidam, Luca and ...
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 2098 - 16
Journal Article
by Klyczek, Karen K and Bonilla, J. Alfred and Jacobs-Sera, Deborah and Adair, Tamarah L and Afram, Patricia and Allen, Katherine G and Archambault, Megan L and Aziz, Rahat M and Bagnasco, Filippa G and Ball, Sarah L and Barrett, Natalie A and Benjamin, Robert C and Blasi, Christopher J and Borst, Katherine and Braun, Mary A and Broomell, Haley and Brown, Conner B and Brynell, Zachary S and Bue, Ashley B and Burke, Sydney O and Casazza, William and Cautela, Julia A and Chen, Kevin and Chimalakonda, Nitish S and Chudoff, Dylan and Connor, Jade A and Cross, Trevor S and Curtis, Kyra N and Dahlke, Jessica A and Deaton, Bethany M and Degroote, Sarah J and DeNigris, Danielle M and DeRuff, Katherine C and Dolan, Milan and Dunbar, David and Egan, Marisa S and Evans, Daniel R and Fahnestock, Abby K and Farooq, Amal and Finn, Garrett and Fratus, Christopher R and Gaffney, Bobby L and Garlena, Rebecca A and Garrigan, Kelly E and Gibbon, Bryan C and Goedde, Michael A and Guerrero Bustamante, Carlos A and Harrison, Melinda and Hartwell, Megan C and Heckman, Emily L and Huang, Jennifer and Hughes, Lee E and Hyduchak, Kathryn M and Jacob, Aswathi E and Kaku, Machika and Karstens, Allen W and Kenna, Margaret A and Khetarpal, Susheel and King, Rodney A and Kobokovich, Amanda L and Kolev, Hannah and Konde, Sai A and Kriese, Elizabeth and Lamey, Morgan E and Lantz, Carter N and Lapin, Jonathan S and Lawson, Temiloluwa O and Lee, In Young and Lee, Scott M and Lee-Soety, Julia Y and Lehmann, Emily M and London, Shawn C and Lopez, A. Javier and Lynch, Kelly C and Mageeney, Catherine M and Martynyuk, Tetyana and Mathew, Kevin J and Mavrich, Travis N and McDaniel, Christopher M and McDonald, Hannah and McManus, C. Joel and Medrano, Jessica E and Mele, Francis E and Menninger, Jennifer E and Miller, Sierra N and Minick, Josephine E and Nabua, Courtney T and Napoli, Caroline K and Nkangabwa, Martha and Oates, Elizabeth A and Ott, Cassandra T and Pellerino, Sarah K and Pinamont, William J and Pirnie, Ross T and Pizzorno, Marie C and Plautz, Emilee J and Pope, Welkin H and Pruett, Katelyn M and Rickstrew, Gabbi and Rimple, Patrick A and ...
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 7, p. e0180517
Journal Article
by Howe, Kerstin and Clark, Matthew D and Torroja, Carlos F and Torrance, James and Berthelot, Camille and Muffato, Matthieu and Collins, John E and Humphray, Sean and McLaren, Karen and Matthews, Lucy and McLaren, Stuart and Sealy, Ian and Caccamo, Mario and Churcher, Carol and Scott, Carol and Barrett, Jeffrey C and Koch, Romke and Rauch, Gerd-Jörg and White, Simon and Chow, William and Kilian, Britt and Quintais, Leonor T and Guerra-Assunção, José A and Zhou, Yi and Gu, Yong and Yen, Jennifer and Vogel, Jan-Hinnerk and Eyre, Tina and Redmond, Seth and Banerjee, Ruby and Chi, Jianxiang and Fu, Beiyuan and Langley, Elizabeth and Maguire, Sean F and Laird, Gavin K and Lloyd, David and Kenyon, Emma and Donaldson, Sarah and Sehra, Harminder and Almeida-King, Jeff and Loveland, Jane and Trevanion, Stephen and Jones, Matt and Quail, Mike and Willey, Dave and Hunt, Adrienne and Burton, John and Sims, Sarah and McLay, Kirsten and Plumb, Bob and Davis, Joy and Clee, Chris and Oliver, Karen and Clark, Richard and Riddle, Clare and Elliott, David and Threadgold, Glen and Harden, Glenn and Ware, Darren and Begum, Sharmin and Mortimore, Beverley and Kerry, Giselle and Heath, Paul and Phillimore, Benjamin and Tracey, Alan and Corby, Nicole and Dunn, Matthew and Johnson, Christopher and Wood, Jonathan and Clark, Susan and Pelan, Sarah and Griffiths, Guy and Smith, Michelle and Glithero, Rebecca and Howden, Philip and Barker, Nicholas and Lloyd, Christine and Stevens, Christopher and Harley, Joanna and Holt, Karen and Panagiotidis, Georgios and Lovell, Jamieson and Beasley, Helen and Henderson, Carl and Gordon, Daria and Auger, Katherine and Wright, Deborah and Collins, Joanna and Raisen, Claire and Dyer, Lauren and Leung, Kenric and Robertson, Lauren and Ambridge, Kirsty and Leongamornlert, Daniel and McGuire, Sarah and Gilderthorp, Ruth and Griffiths, Coline and Manthravadi, Deepa and Nichol, Sarah and Barker, Gary and ...
Nature (London), ISSN 1476-4687, 2013, Volume 496, Issue 7446, pp. 498 - 503
Journal Article
by Deelen, Joris and Evans, Daniel S and Arking, Dan E and Tesi, Niccolò and Nygaard, Marianne and Liu, Xiaomin and Wojczynski, Mary K and Biggs, Mary L and van der Spek, Ashley and Atzmon, Gil and Ware, Erin B and Sarnowski, Chloé and Smith, Albert V and Seppälä, Ilkka and Cordell, Heather J and Dose, Janina and Amin, Najaf and Arnold, Alice M and Ayers, Kristin L and Barzilai, Nir and Becker, Elizabeth J and Beekman, Marian and Blanché, Hélène and Christensen, Kaare and Christiansen, Lene and Collerton, Joanna C and Cubaynes, Sarah and Cummings, Steven R and Davies, Karen and Debrabant, Birgit and Deleuze, Jean-François and Duncan, Rachel and Faul, Jessica D and Franceschi, Claudio and Galan, Pilar and Gudnason, Vilmundur and Harris, Tamara B and Huisman, Martijn and Hurme, Mikko A and Jagger, Carol and Jansen, Iris and Jylhä, Marja and Kähönen, Mika and Karasik, David and Kardia, Sharon L. R and Kingston, Andrew and Kirkwood, Thomas B. L and Launer, Lenore J and Lehtimäki, Terho and Lieb, Wolfgang and Lyytikäinen, Leo-Pekka and Martin-Ruiz, Carmen and Min, Junxia and Nebel, Almut and Newman, Anne B and Nie, Chao and Nohr, Ellen A and Orwoll, Eric S and Perls, Thomas T and Province, Michael A and Psaty, Bruce M and Raitakari, Olli T and Reinders, Marcel J. T and Robine, Jean-Marie and Rotter, Jerome I and Sebastiani, Paola and Smith, Jennifer and Sørensen, Thorkild I. A and Taylor, Kent D and Uitterlinden, André G and van der Flier, Wiesje and van der Lee, Sven J and van Duijn, Cornelia M and van Heemst, Diana and Vaupel, James W and Weir, David and Ye, Kenny and Zeng, Yi and Zheng, Wanlin and Holstege, Henne and Kiel, Douglas P and Lunetta, Kathryn L and Slagboom, P. Eline and Murabito, Joanne M
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 3669 - 14
textabstractHuman longevity is heritable, but genome-wide association (GWA) studies have had limited success. Here, we perform two meta-analyses of GWA studies... 
SURVIVAL | LIFE-SPAN | GWAS | CONFIRMS APOE | MULTIDISCIPLINARY SCIENCES | HEALTH | PREVALENCE | LD SCORE REGRESSION | LOCUS | HERITABILITY | AGE | Heat-Shock Proteins - genetics | Genome-Wide Association Study | Apolipoprotein E4 - genetics | Longevity - genetics | Apolipoprotein E2 - genetics | Humans | Phenotypes | Apolipoprotein E | Genes | Association analysis | Genomes | Longevity | Gene expression | Survival | Age | Life Sciences | Genetics
Journal Article