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science & technology (9) 9
humans (6) 6
antineoplastic agents - pharmacology (4) 4
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1. Full Text Rolling Resistance Performance of Passenger Tires During Warm-Up - Speed Load, and Inflation Pressure Effects
by Warholic, T. C., author
SAE technical paper series, Volume 820455.
Tires and traction
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2. Full Text Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2
by Sarah K. Knutson and Natalie M. Warholic and Tim J. Wigle and Christine R. Klaus and Christina J. Allain and Alejandra Raimondi and Margaret Porter Scott and Richard Chesworth and Mikel P. Moyer and Robert A. Copeland and Victoria M. Richon and Roy M. Pollock and Kevin W. Kuntz and Heike Keilhack
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 5/2013, Volume 110, Issue 19, pp. 7922 - 7927
Cell culture techniques | Cell lines | Cell cycle | Histones | Rhabdoid tumors | Gene expression | Heterologous transplantation | Tumors | Cancer | Apoptosis | Epigenetic cancer therapy | EZH2 inhibitor | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Polycomb Repressive Complex 2 - antagonists & inhibitors | Neoplasm Transplantation | Cell Proliferation | Epigenesis, Genetic | Humans | Gene Expression Profiling | Enhancer of Zeste Homolog 2 Protein | Neoplasms - drug therapy | Rhabdoid Tumor - enzymology | Neoplasms - therapy | Animals | Rhabdoid Tumor - genetics | Biphenyl Compounds - pharmacology | Drug Design | HEK293 Cells | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Mice | Pyridines - pharmacology | Histones - metabolism | Neoplasms - pathology | Methyltransferases | Physiological aspects | Genetic aspects | Research | Health aspects | Proteins | Rodents | Oncology | Biochemistry | Bioavailability | Index Medicus | Biological Sciences | epigenetic cancer therapy
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3. Full Text Preclinical evidence of anti-tumor activity induced by EZH2 inhibition in human models of synovial sarcoma
by Kawano, Satoshi and Grassian, Alexandra R and Tsuda, Masumi and Knutson, Sarah K and Warholic, Natalie M and Kuznetsov, Galina and Xu, Shanqin and Xiao, Yonghong and Pollock, Roy M and Smith, Jesse S and Kuntz, Kevin K and Ribich, Scott and Minoshima, Yukinori and Matsui, Junji and Copeland, Robert A and Tanaka, Shinya and Keilhack, Heike
PloS one, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, pp. e0158888 - e0158888
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Oncogene Proteins, Fusion - metabolism | Polycomb Repressive Complex 2 - genetics | Humans | SMARCB1 Protein - genetics | Sarcoma, Synovial - metabolism | Xenograft Model Antitumor Assays | SMARCB1 Protein - metabolism | Animals | Sarcoma, Synovial - genetics | Mice, Nude | Oncogene Proteins, Fusion - genetics | Sarcoma, Synovial - drug therapy | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Mice | Mice, Inbred BALB C | Polycomb Repressive Complex 2 - metabolism | Development and progression | Care and treatment | Genetic aspects | Research | Sarcoma | Gene expression | Animal models | Sucrose | Transcription | Xenotransplantation | Methyltransferase | Homeostasis | Metastasis | Anticancer properties | Proteins | Antitumor agents | Enzymatic activity | Xenografts | Inhibition | Catalysis | Fusion protein | Chromosomes | Sugars | Synovial sarcoma | Pharmacology | Bioavailability | Substrates | Chromatin remodeling | Polycomb group proteins | Lysine | Cell death | Medical prognosis | SWI/SNF complex | Mutation | Methylation | Histone H3 | Tumors | Cancer | Index Medicus
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4. Full Text Influence of drag-reducing polymers on turbulence: effects of Reynolds number, concentration and mixing
by Warholic, M. D and Massah, H and Hanratty, T. J
Experiments in fluids, ISSN 0723-4864, 10/1999, Volume 27, Issue 5, pp. 461 - 472
Mechanics | Engineering | Technology | Engineering, Mechanical | Science & Technology | Fundamental areas of phenomenology (including applications) | Fluid dynamics | Turbulent flows, convection, and heat transfer | Turbulence control | Instrumentation for fluid dynamics | Exact sciences and technology | Physics
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5. Full Text Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing
by Michael Shtutman and Anil Maliyekkel and Yu Shao and C. Steven Carmack and Mirza Baig and Natalie Warholic and Kelly Cole and Eugenia V. Broude and Timothy T. Harkins and Ye Ding and Igor B. Roninson and Alexander Varshavsky
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 4/2010, Volume 107, Issue 16, pp. 7377 - 7382
Datasets | Cell growth | Complementary DNA | Genetic vectors | RNA | Cell lines | Small interfering RNA | Libraries | Sequencing | Cells | Lentiviral vectors | RNA interference | Cancer targets | Functional genomics | siRNA design | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Engineering - methods | Gene Library | Humans | DNA - metabolism | Genetic Techniques | Breast Neoplasms - metabolism | Breast Neoplasms - genetics | Cell Line, Tumor | Carcinoma - genetics | Female | Lentivirus - genetics | Models, Genetic | DNA, Complementary - metabolism | Sequence Analysis, DNA - methods | RNA, Small Interfering - metabolism | Genetic research | Genetic aspects | DNA testing | Research | Cancer | Enzymes | Ribonucleic acid--RNA | Genes | Index Medicus | Biological Sciences | functional genomics | cancer targets | lentiviral vectors
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6. Full Text Synergistic anti-tumor activity of EZH2 inhibitors and glucocorticoid receptor agonists in models of germinal center non-Hodgkin lymphomas
by Knutson, Sarah K and Warholic, Natalie M and Johnston, L. Danielle and Klaus, Christine R and Wigle, Tim J and Iwanowicz, Dorothy and Littlefield, Bruce A and Porter-Scott, Margaret and Smith, Jesse J and Moyer, Mikel P and Copeland, Robert A and Pollock, Roy M and Kuntz, Kevin W and Raimondi, Alejandra and Keilhack, Heike
PloS one, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e111840 - e111840
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Neoplasm Transplantation | Vincristine - pharmacology | Humans | Receptors, Glucocorticoid - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Receptors, Glucocorticoid - agonists | Dexamethasone - pharmacology | Female | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Drug Evaluation, Preclinical | Lymphoma, Non-Hodgkin - drug therapy | Enhancer of Zeste Homolog 2 Protein - metabolism | Random Allocation | Mice, SCID | Prednisolone - pharmacology | Animals | Cyclophosphamide - pharmacology | Lymphoma, Non-Hodgkin - metabolism | Cell Line, Tumor | Glucocorticoids - pharmacology | Prednisone - pharmacology | Doxorubicin - pharmacology | Pyridones - pharmacology | Care and treatment | Corticosteroids | Fluocinolone acetonide | Central nervous system depressants | Analysis | Histones | Models | Non-Hodgkin's lymphomas | Immunosuppressive agents | Steroids | Cancer | Enzymes | Dexamethasone | Glucocorticoids | Research & development--R&D | Gene expression | Lymphoma | Anticancer properties | Signal transduction | Cell growth | Inhibitors | Mutation | Prednisolone | Apoptosis | Index Medicus | Research & development | R&D
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7. Full Text A study with particle-image velocimetry of the influence of drag-reducing polymers on the structure of turbulence
by Warholic, M. D and Heist, D. K and Katcher, M and Hanratty, T. J
Experiments in fluids, ISSN 0723-4864, 11/2001, Volume 31, Issue 5, pp. 474 - 483
Mechanics | Engineering | Technology | Engineering, Mechanical | Science & Technology | Fundamental areas of phenomenology (including applications) | Fluid dynamics | Turbulent flows, convection, and heat transfer | Turbulence control | Instrumentation for fluid dynamics | Exact sciences and technology | Flows in ducts, channels, nozzles, and conduits | Physics
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8. Full Text Turbulent flow in a channel at a low Reynolds number
by Günther, A and Papavassiliou, D. V and Warholic, M. D and Hanratty, T. J
Experiments in fluids, ISSN 0723-4864, 10/1998, Volume 25, Issue 5, pp. 503 - 511
Mechanics | Engineering | Technology | Engineering, Mechanical | Science & Technology | Fundamental areas of phenomenology (including applications) | Fluid dynamics | Flows in ducts, channels, nozzles, and conduits | Instrumentation for fluid dynamics | Physics | Exact sciences and technology
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9. Full Text Correction: Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma
by Kawano, Satoshi and Grassian, Alexandra R and Tsuda, Masumi and Knutson, Sarah K and Warholic, Natalie M and Kuznetsov, Galina and Xu, Shanqin and Xiao, Yonghong and Pollock, Roy M and Smith, Jesse J and Kuntz, Kevin W and Ribich, Scott and Minoshima, Yukinori and Matsui, Junji and Copeland, Robert A and Tanaka, Shinya and Keilhack, Heike
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 1, pp. e0170539 - e0170539
Antitumor agents | Sarcoma | Synovial sarcoma | Anticancer properties
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10. Full Text A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
by Knutson, Sarah K and Wigle, Tim J and Warholic, Natalie M and Sneeringer, Christopher J and Allain, Christina J and Klaus, Christine R and Sacks, Joelle D and Raimondi, Alejandra and Majer, Christina R and Song, Jeffrey and Scott, Margaret Porter and Jin, Lei and Smith, Jesse J and Olhava, Edward J and Chesworth, Richard and Moyer, Mikel P and Richon, Victoria M and Copeland, Robert A and Keilhack, Heike and Pollock, Roy M and Kuntz, Kevin W
Nature chemical biology, ISSN 1552-4450, 2012, Volume 8, Issue 11, pp. 890 - 896
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Polycomb Repressive Complex 2 - antagonists & inhibitors | Polycomb Repressive Complex 2 - genetics | Histones - chemistry | Humans | Structure-Activity Relationship | Dose-Response Relationship, Drug | Lymphoma - drug therapy | Enzyme Inhibitors - chemistry | Lymphoma - enzymology | Lymphoma - pathology | Antineoplastic Agents - pharmacology | Lysine - metabolism | Molecular Structure | Cell Death - drug effects | Indazoles - chemistry | Enzyme Inhibitors - pharmacology | Lymphoma - genetics | Antineoplastic Agents - chemistry | Enhancer of Zeste Homolog 2 Protein | Indazoles - pharmacology | Point Mutation | Methylation - drug effects | Cell Proliferation - drug effects | Histones - metabolism | Pyridones - chemistry | Cell Cycle - drug effects | Polycomb Repressive Complex 2 - metabolism | Pyridones - pharmacology | Catalysts | Mutagenesis | Cancer therapies | Lymphoma | Index Medicus
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11. Full Text Mortality in elderly patients with hyperostotic disease of the cervical spine after fracture: an age- and sex-matched study
by Schoenfeld, Andrew J., MD and Harris, Mitchel B., MD, FACS and McGuire, Kevin J., MD and Warholic, Natalie, MA and Wood, Kirkham B., MD and Bono, Christopher M., MD
The spine journal, ISSN 1529-9430, 2011, Volume 11, Issue 4, pp. 257 - 264
Orthopedics | Cervical spine trauma | Diffuse idiopathic skeletal hyperostosis | Elderly | Mortality | Ankylosing spondylitis | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cervical Vertebrae | Humans | Spinal Fractures - mortality | Kaplan-Meier Estimate | Male | Spondylitis, Ankylosing - complications | Case-Control Studies | Hyperostosis, Diffuse Idiopathic Skeletal - mortality | Spondylitis, Ankylosing - mortality | Spinal Fractures - complications | Aged, 80 and over | Female | Aged | Retrospective Studies | Hyperostosis, Diffuse Idiopathic Skeletal - complications | Medical research | Orthopedic surgery | Comorbidity | Patient outcomes | Rheumatoid arthritis | Medicine, Experimental | Aged patients | Index Medicus
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