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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 08/2019, Volume 200, Issue 3, pp. 370 - 380
Journal Article
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 08/2019
Multidrug-resistant tuberculosis is an alarming threat and targeted deep sequencing (DS) may be an effective method for rapid identification of drug-resistant... 
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 14854 - 9
Xpert MTB/RIF (Xpert) is a widely-used test for tuberculosis (TB) and rifampicin-resistance. Second-line drug susceptibility testing (DST), which is... 
DIAGNOSIS | RESISTANT TUBERCULOSIS | ASSAY | MULTIDISCIPLINARY SCIENCES | IMPLEMENTATION | TIME | TREATMENT INITIATION | KHAYELITSHA | Bacilli | Purification | Tuberculosis | Genotyping | Spoligotyping | Rifampin | Deoxyribonucleic acid--DNA | Patients
Journal Article
eLife, ISSN 2050-084X, 03/2015, Volume 2015, Issue 4
Whole genome sequencing has revealed that most cases of tuberculosis in a high-incidence setting in Malawi were caused by just one lineage of the bacterium... 
TUBERCULOSIS | BIOLOGY | Genes, Bacterial | Tuberculosis - microbiology | High-Throughput Nucleotide Sequencing | Tuberculosis - genetics | Humans | Mycobacterium tuberculosis - genetics | Fighting | Epidemics | Tuberculosis | Bacteria | Infections | Genomes | Research | Molecular biology | Drug resistance | Patients | Epidemiology
Journal Article
Infection, Genetics and Evolution, ISSN 1567-1348, 10/2019, Volume 74, p. 103937
Rifampicin was discovered in 1965 and remains one of the most important drugs in tuberculosis treatment that is valued for its sterilizing activity and ability... 
Rifampicin | Trial | Mycobacterium tuberculosis | High dose
Journal Article
Tuberculosis, ISSN 1472-9792, 01/2018, Volume 108, p. 169
Nucleoid associated proteins (NAPs) are known organisers of chromosomal structure and regulators of transcriptional expression. The number of proposed NAPs in... 
Proteins | Transcription factors | Regulators | Transcription | Gene regulation | Classification | Gene expression | Drug development | Chromosomes | Deoxyribonucleic acid--DNA
Journal Article
The Lancet Respiratory Medicine, ISSN 2213-2600, 10/2019, Volume 7, Issue 10, pp. 892 - 906
The diverse microbial communities within our bodies produce metabolites that modulate host immune responses. Even the microbiome at distal sites has an... 
Journal Article
Infection, Genetics and Evolution, ISSN 1567-1348, 11/2019, Volume 75, p. 103948
Recurrent tuberculosis (TB) after successful TB treatment occurs due to endogenous reactivation (relapse) or exogenous reinfection. We revisited the... 
Tuberculosis | Recurrent tuberculosis | Mycobacterium tuberculosis | Whole genome sequencing
Journal Article
PLOS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e59414
Journal Article
The Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 01/2016, Volume 71, Issue 1, p. 17
  The emergence of drug resistance continues to plague TB control, with a global increase in the prevalence of MDR-TB. This acts as a gateway to XDR-TB and... 
Genotype & phenotype | Tuberculosis | Antibiotics | Medical treatment | Bacteria | Drug resistance
Journal Article
Vaccine, ISSN 0264-410X, 12/2013, Volume 31, Issue 50, p. 5934
  The purpose of this simple study was to characterize a panel of clinical isolates ofMycobacterium tuberculosisobtained from the Western Cape region of South... 
Candidates | Tuberculosis | Lungs | Colleges & universities | Infections | Vaccines | Drug resistance | Drug dosages
Journal Article
Journal of Research Administration, ISSN 1539-1590, 03/2017, Volume 48, Issue 1, p. 100
Journal Article
International Journal of Mycobacteriology, ISSN 2212-5531, 2016, Volume 5, Issue 5, pp. S67 - S67
Contrary to classical dogma, molecular epidemiological studies and mathematical modeling clearly show that the global drug-resistant tuberculosis (TB) epidemic... 
Infectious Disease | Medical Education | Drug resistance | Tuberculosis | Diagnosis
Journal Article
BMC Microbiology, ISSN 1471-2180, 03/2006, Volume 6, Issue 1, pp. 23 - 23
Journal Article