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Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2006, Volume 328, pp. 159 - 175
Multidimensional chromatography coupled to mass spectrometry is an emerging technique for the analysis of complex protein mixtures. One approach in this... 
Computational Biology - methods | Animals | Spectrometry, Mass, Electrospray Ionization | Time Factors | Databases, Protein | Humans | Mass Spectrometry | Chromatography - methods | Proteome | Chromatography, High Pressure Liquid | Proteins - chemistry | Proteomics - methods
Journal Article
Methods (San Diego, Calif.), ISSN 1046-2023, 08/2019
Detecting subnetworks in large networks is of great interest. Recently, we developed a topological score framework for the analysis of protein interaction... 
Journal Article
PROTEOMICS, ISSN 1615-9853, 09/2016, Volume 16, Issue 18, p. NA
Journal Article
PROTEOMICS, ISSN 1615-9853, 09/2016, Volume 16, Issue 18, p. NA
Journal Article
Molecular Cell, ISSN 1097-2765, 2010, Volume 37, Issue 3, pp. 429 - 437
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 11/2018, Volume 46, Issue 21, pp. 11202 - 11213
Abstract DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase 1A, which is linked to mental retardation and microcephaly, is a member of the CMGC... 
COMPLEX | PROTEIN | INHIBITION | GENE | MINIBRAIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENOME-WIDE | ACETYLTRANSFERASE | HAPLOINSUFFICIENCY | REVEALS | Gene regulation, Chromatin and Epigenetics
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 10/2018, Volume 17, Issue 10, pp. 3586 - 3592
The use of mass spectrometry as a tool to detect proteins of biological interest has become a cornerstone of proteomics. The popularity of mass... 
mass spectrometry | Orbitrap Lumos | sensitivity | data-dependent acquisition | limit of detection | Proteomics | INSTRUMENTATION | SPECIFICITY | SHOTGUN PROTEOMICS | COVERAGE | QUANTITATION | BIOCHEMICAL RESEARCH METHODS | IDENTIFICATION TECHNOLOGY
Journal Article
JOURNAL OF PROTEOME RESEARCH, ISSN 1535-3893, 04/2019, Volume 18, Issue 4, pp. 1857 - 1869
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 12, p. E2734
Eukaryotic gene regulation is a complex process, often coordinated by the action of tens to hundreds of proteins. Although previous biochemical studies have... 
CRISPR | Regulators | Chromatin | Histone H2A | Drosophila | Gene regulation | Mass spectroscopy | Gene expression | Loci | Screens | Proteins | Proteomics | Gene loci | Nuclease | Mass spectrometry
Journal Article
Journal of Cell Science, ISSN 0021-9533, 01/2019, Volume 132, Issue 2, p. jcs214072
Metazoans contain two homologs of the Gcn5-binding protein Ada2, Ada2a and Ada2b, which nucleate formation of the ATAC and SAGA complexes, respectively. In... 
Gcn5 | Histone acetylation | Dbf4 | Gene expression | Cell cycle | ENCODES | INITIATION | SAGA | DNA-REPLICATION | CELL BIOLOGY | ORIGIN ACTIVITY | AMPLIFICATION | CHROMATIN-MODIFYING COMPLEXES | GENE-EXPRESSION | S-PHASE | MELANOGASTER
Journal Article
PROTEOMICS, ISSN 1615-9853, 09/2016, Volume 16, Issue 18, pp. 2444 - 2447
Journal Article
Analytical Chemistry, ISSN 0003-2700, 05/2015, Volume 87, Issue 9, p. 4749
  In a previous study, we demonstrated that spectral counts-based label-free proteomic quantitation could be improved by distributing peptides shared between... 
Proteins | Peptides | Proteomics | Regression analysis
Journal Article
Analytical Chemistry (Washington), ISSN 0003-2700, 05/2015, Volume 87, Issue 9, pp. 4749 - 4749
In a previous study, we demonstrated that spectral counts-based label-free proteomic quantitation could be improved by distributing peptides shared between... 
Peptides | Proteomics | Parents | Abundance | Spectra | Distributing | Variance | Chromatography | Fragmentation
Journal Article
Proteomics, ISSN 1615-9853, 09/2016, Volume 16, Issue 18, p. NA
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 03/2011, Volume 36, Issue 3, p. 170
Proteomic analysis of biological samples plays an increasing role in modern research. Although the application of proteomics technologies varies across many... 
Proteins | Studies | Proteomics | Biochemistry | Mass spectrometry
Journal Article
Genome Biology, ISSN 1474-7596, 03/2016, Volume 17, Issue 1, p. 48
Protein complexes are dynamic. A new analysis of two quantitative proteomic datasets reveals cell type-specific changes in the stoichiometry of complexes,... 
DYNAMICS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | Humans | Proteomics | Protein Interaction Mapping | Datasets | Proteins | Stoichiometry | Stem cells | Genomes | Biology | Gene expression
Journal Article
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