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Diabetes, obesity & metabolism, ISSN 1463-1326, 2019, Volume 22, Issue 1, pp. 66 - 78
Aim To assess glycaemic control and factors associated with poor glycaemic control at initiation of second‐line therapy in the DISCOVER programme. Materials... 
glycaemic control | type 2 diabetes | observational study | Hemoglobin | Glucose | Diabetes | Regression analysis | Diabetes mellitus (non-insulin dependent) | Patients | Index Medicus | Original
Journal Article
Journal of diabetes investigation, ISSN 2040-1116, 2019, Volume 10, Issue 1, pp. 84 - 93
Aims/Introduction Pancreatic β‐cell dysfunction contributes to type 2 diabetes mellitus progression. Drugs that improve insulin secretion might be a valuable... 
Pancreatic β‐cells | Diabetes mellitus | Hyperglycemic clamp | Pancreatic β-cells | METFORMIN | GLYCEMIC CONTROL | AS1535907 | Pancreatic beta-cells | TOLERANCE | INSULIN-SECRETION | EXENATIDE | INTRAVENOUS GLUCOSE | MASS | ENDOCRINOLOGY & METABOLISM | 1ST-PHASE | GPR119 AGONIST | Peptides | Secretion | Hemoglobin | Diabetes | Glucose | Pancreas | Diabetes mellitus (non-insulin dependent) | Insulin | Patients | Cholesterol | Original
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 04/2019, Volume 321, Issue 15, pp. 1466 - 1480
Journal Article
PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 9, p. e0222598
... Yamashiro 3, Hirotaka Watada 1,2,5,6 Introduction Bacterial translocation is defined by translocation of live bacteria or their components, such as lipopolysaccharide... 
OBESITY | MECHANISMS | SECRETION | LIPOPOLYSACCHARIDE-BINDING PROTEIN | CHAIN FATTY-ACIDS | MULTIDISCIPLINARY SCIENCES | Carrier Proteins - blood | Bacterial Translocation - physiology | Inflammation - microbiology | C-Peptide - blood | Diabetes Mellitus, Type 2 - microbiology | Acute-Phase Proteins | Humans | Middle Aged | Membrane Glycoproteins - blood | Male | Biomarkers - blood | Diabetes Mellitus, Type 2 - metabolism | Inflammation - blood | Asian Continental Ancestry Group | Diabetes Mellitus, Type 2 - blood | Inflammation - metabolism | C-Reactive Protein - metabolism | Interleukin-6 - blood | Female | Retrospective Studies | Endotoxemia - blood | Endotoxemia - metabolism | Endotoxemia - microbiology | Diabetics | Care and treatment | Microbiota (Symbiotic organisms) | Research | Diagnosis | Health aspects | Bacteremia | Lipopolysaccharides | C-reactive protein | Multiple regression analysis | Laboratories | Interleukin | Interleukin 6 | Proteins | Body mass index | Registration | Bacteria | Physiology | Diabetes mellitus (non-insulin dependent) | Endotoxemia | University graduates | Translocation | Obesity | Fasting | Sensitivity analysis | Liver diseases | Diabetes mellitus | Inflammation | Regression analysis | Metabolism | Fatty acids | Patients | Cholesterol | Inflammatory bowel disease | Medicine | Probiotics | Hospitals | Body mass | Body size | Insulin resistance | Diabetes | Kidney diseases | Endocrinology
Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2019, Volume 68, Issue Supplement 1, p. 148-OR
Journal Article
Journal of diabetes investigation, ISSN 2040-1116, 01/2019, Volume 10, Issue 1, p. 84
Journal Article
Journal of diabetes investigation, ISSN 2040-1116, 2019, Volume 10, Issue 2, pp. 216 - 218
[...]to investigate the causal relationship between decreased islet expression of LRP‐1 and decreased β‐cell function, they generated β‐cells specific LRP‐1... 
HOMEOSTASIS | DEFICIENCY | ENDOCRINOLOGY & METABOLISM | Lipids | Smooth muscle | Roles | Adipocytes | Glucose | Metabolism | Kinases | Cholesterol | Protein turnover | Proteins | Signal transduction | Glucose metabolism | Lipoproteins | Atherosclerosis | Insulin resistance | Receptor density | Physiology | Diabetes | Lipid metabolism | Pancreas | Alzheimers disease | Commentaries
Journal Article
Journal of applied physiology (Bethesda, Md. : 1985), ISSN 8750-7587, 01/2019, Volume 126, Issue 1, pp. 170 - 182
Type 2 diabetes is characterized by reduced contractile force production and increased fatigability of skeletal muscle. While the maintenance of Ca2+... 
FIBER | SPORT SCIENCES | PHYSIOLOGY | ECCENTRIC CONTRACTIONS | INSULIN-RESISTANCE | CALCIUM-RELEASE | IN-VIVO | MOUSE MODEL | SARCALUMENIN | STRENGTH | ACCUMULATION | BETA-CELL FUNCTION
Journal Article
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 05/2019, Volume 83, Issue 6, pp. 1330 - 1337
Background: Although the subclinical left ventricular (LV) dysfunction caused by diabetes mellitus (DM) results in a high risk of death and heart failure, the... 
Diabetic cardiomyopathy | Layer-specific strain | Cardiac dysfunction | Type 1 diabetes mellitus | MYOCARDIAL STRAIN | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | HEART-FAILURE | CARDIOMYOPATHY | DEFORMATION | DIASTOLIC DYSFUNCTION | TRANSMURAL STRAIN | IMPAIRMENT | LEFT-VENTRICULAR DYSFUNCTION | LONGITUDINAL STRAIN
Journal Article
Diabetes, obesity & metabolism, ISSN 1463-1326, 2019, Volume 21, Issue 12, pp. 2694 - 2703
Aims To investigate the efficacy and safety of insulin degludec/liraglutide (IDegLira) compared with 50 U insulin degludec (degludec) or less in Japanese... 
liraglutide | basal insulin | type 2 diabetes | hypoglycaemia | randomized trial
Journal Article
Diabetes therapy, ISSN 1869-6961, 2019, Volume 11, Issue 1, pp. 331 - 339
DUAL II Japan (NCT02911948) was a 26-week, phase 3a randomized, treat-to-target trial which compared the efficacy and safety of IDegLira with degludec in 210... 
Type 2 diabetes | METFORMIN | FIXED-RATIO COMBINATION | EFFICACY | SAFETY | Hypoglycemia | Premixed insulin | LIRAGLUTIDE IDEGLIRA | DEGLUDEC | Basal insulin | ENDOCRINOLOGY & METABOLISM | Randomized trial | PEOPLE | Liraglutide | DEGLUDEC/LIRAGLUTIDE | Brief Report
Journal Article