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Journal Article
Cancer Research, ISSN 0008-5472, 1988, Volume 48, Issue 5, pp. 1238 - 1243
Fifty-one primary human breast tumors were analyzed for amplification of the c-erbB-2 protooncogene. Thirteen (25%) of the DNA samples contained multiple gene... 
ONCOLOGY | Breast Neoplasms - genetics | Gene Amplification | Lymph Nodes - pathology | Breast Neoplasms - pathology | Cell Nucleus - pathology | Humans | Proto-Oncogene Proteins - analysis | Female | Receptor, ErbB-2 | Receptors, Estrogen - analysis | Proto-Oncogenes
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/1987, Volume 40, Issue 2, pp. 246 - 254
Two synthetic peptides from the predicted sequence of the human c‐erbB‐2 protein were synthesized and used to raise antisera in rabbits. The sequences chosen... 
ONCOLOGY | Ureter - analysis | Amino Acid Sequence | Immune Sera - immunology | Rabbits | Humans | Cells, Cultured | Rats | Animals | Gene Amplification | Kidney - analysis | Mouth Mucosa - analysis | Proto-Oncogene Proteins - analysis | Proto-Oncogene Proteins - immunology | ErbB Receptors - analysis | Neoplasms - analysis
Journal Article
The Journal of Pathology, ISSN 0022-3417, 08/1987, Volume 152, Issue 4, pp. 297 - 307
Journal Article
Biochemical Journal, ISSN 0264-6021, 05/2007, Volume 404, Issue 1, pp. 15 - 21
The PI3Ks (phosphatidylinositol 3-kinases) regulate cellular signalling networks that are involved in processes linked to the survival, growth, proliferation,... 
Phosphatidylinositol 3-kinase (PI3k) | Valosin-containing protein (VCP) | Chemical proteomic strategy | LY294002 | Brd4 | 3-kinase (PI3K) | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL ANTIGEN | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | WORTMANNIN | chemical proteomic strategy | valosin-containing protein (VCP) | phosphatidylinositol | B-CELL | PATHWAY | BRD4 BINDS | TARGETS | PHOSPHOINOSITIDE 3-KINASES | PROTEIN-KINASE INHIBITORS | Cell Line | Cell Survival - drug effects | Humans | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Proteins - genetics | Animals | Signal Transduction - drug effects | Culture Media | Models, Animal | Kinetics | Chromones - pharmacology | Proteins - chemical synthesis | Proteins - antagonists & inhibitors | VCP | WT, wild-type | MS, liquid chromatography–electrospray–ionization tandem MS | VCP, valosin-containing protein | AA ATP, hydrolysis mutant form of p97 | EAS, epoxy-activated Sepharose | GSK3, glycogen synthase kinase 3 | Wm, Wortmannin | ALDH, aldehyde dehydrogenase | PXDK, pyridoxal kinase | PIP3, phosphatidylinositol (3,4,5) triphosphate | PI3K, phosphatidylinositol 3-kinase | DMF, dimethylformamide | mTOR, mammalian target of rapamycin | Brd, bromodomain | PI3KC3, PI3K, class 3 | CK2, casein kinase 2 | LC–ESI–MS | phosphatidylinositol 3-kinase (PI3K) | FCS, fetal calf serum
Journal Article
Annual Review of Cell and Developmental Biology, ISSN 1081-0706, 11/2001, Volume 17, Issue 1, pp. 615 - 675
The phosphoinositide 3-kinase (PI3K) family of enzymes is recruited upon growth factor receptor activation and produces 3′ phosphoinositide lipids. The lipid... 
gene targeting | development | 3-phosphoinositide | insulin | PROTEIN-KINASE-B | NITRIC-OXIDE SYNTHASE | DEVELOPMENTAL BIOLOGY | PHOSPHOENOLPYRUVATE CARBOXYKINASE GENE | CORONARY HEART-DISEASE | BRUTONS TYROSINE KINASE | PTEN TUMOR-SUPPRESSOR | NF-KAPPA-B | INSULIN-RECEPTOR SUBSTRATE-1 | HUMAN PHOSPHATIDYLINOSITOL 3-KINASE | ENDOTHELIAL GROWTH-FACTOR
Journal Article