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1. Full Text Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts
by Alexander, Michael and Loomis, A. K and Lei, Johan and Duarte-Salles, T and Prieto-Alhambra, D and Ansell, D and Pasqua, Alessano and Lapi, Francesco and Rijnbeek, Peter and Mosseveld, Mees and Waterworth, Dawn and Kenick, S and Sattar, Naveed and Alazawi, W
BMC medicine, ISSN 1741-7015, 05/2019, Volume 17, Issue 1, pp. 95 - 95
Cirrhosis | Population | NAFLD | NASH | Hepatocellular cancer | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Carcinoma, Hepatocellular - epidemiology | Prognosis | Humans | Middle Aged | Netherlands - epidemiology | Liver Neoplasms - complications | Male | Case-Control Studies | Liver Cirrhosis - epidemiology | Non-alcoholic Fatty Liver Disease - complications | Liver Neoplasms - epidemiology | Carcinoma, Hepatocellular - complications | Adult | Female | Liver Cirrhosis - etiology | Liver Cirrhosis - diagnosis | Carcinoma, Hepatocellular - diagnosis | Risk Factors | Europe - epidemiology | Liver Neoplasms - diagnosis | Spain - epidemiology | Non-alcoholic Fatty Liver Disease - diagnosis | Liver Cirrhosis - pathology | Italy - epidemiology | Aged | Non-alcoholic Fatty Liver Disease - epidemiology | United Kingdom - epidemiology | Cohort Studies | Adults | Fatty liver | Diagnosis | Liver cirrhosis | Health aspects | Risk factors | Health care | Hypertension | Liver diseases | Control methods | Liver | World population | Mortality | Diabetes mellitus | Health risks | Medical records | Risk | Hepatocellular carcinoma | Patients | Data bases | Databases | Chronic illnesses | Smoking | Index Medicus
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2. Full Text Genome-wide association analysis identifies 20 loci that influence adult height
by Weedon, Michael N and Lango, Hana and Lindgren, Cecilia M and Wallace, Chris and Evans, David M and Mangino, Massimo and Freathy, Rachel M and Perry, John R. B and Stevens, Suzanne and Hall, Alistair S and Samani, Nilesh J and Shields, Beverly and Prokopenko, Inga and Farrall, Martin and Dominiczak, Anna and Johnson, Toby and Bergmann, Sven and Beckmann, Jacques S and Vollenweider, Peter and Waterworth, Dawn M and Mooser, Vincent and Palmer, Colin N. A and Morris, Andrew D and Ouwehand, Willem H and Zhao, Jing Hua and Li, Shengxu and Loos, Ruth J. F and Barroso, Inês and Deloukas, Panagiotis and Sandhu, Manjinder S and Wheeler, Eleanor and Soranzo, Nicole and Inouye, Michael and Wareham, Nicholas J and Caulfield, Mark and Munroe, Patricia B and Hattersley, Andrew T and McCarthy, Mark I and Frayling, Timothy M and Diabet Genetics Initiat and Cambridge GEM Consortium and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and Diabetes Genetics Initiative and The Wellcome Trust Case Control Consortium
Nature genetics, ISSN 1061-4036, 05/2008, Volume 40, Issue 5, pp. 575 - 583
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Extracellular Matrix Proteins - genetics | Humans | Middle Aged | Genotype | Male | Body Height - genetics | Hedgehog Proteins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome, Human | Neoplasm Proteins - genetics | Stature | Quantitative trait loci | Genetic variation | Physiological aspects | Genetic aspects | Research | Identification and classification | Studies | Genetic research | Genetics | Gene loci | Height | Genes | Index Medicus
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3. Full Text Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease
by Alexander, Michael and Loomis, A. K and Fairburn-Beech, J and Lei, Johan and Duarte-Salles, T and Prieto-Alhambra, D and Ansell, D and Pasqua, Alessano and Lapi, Francesco and Rijnbeek, Peter and Mosseveld, Mees and Avillach, P and Egger, Pascal and Kenick, S and Waterworth, Dawn and Sattar, Naveed and Alazawi, W
BMC medicine, ISSN 1741-7015, 01/2018, Volume 16, Issue 1, pp. 130 - 130
epidemiology | NAFLD | NASH | population | Population | Epidemiology | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Non-alcoholic Fatty Liver Disease - pathology | Prevalence | Humans | Middle Aged | Risk Factors | Non-alcoholic Fatty Liver Disease - diagnosis | Female | Male | Databases, Factual - trends | Disease Progression | Incidence | Usage | Fatty liver | Liver diseases | Causes of | Medical records | Diagnosis | Risk factors | Liver | Mortality | Health care policy | Metabolism | Patients | Estimates | Primary care | Studies | Databases | Hepatology | Diagnostic systems | Diabetes | Clinical medicine | Electronic health records | Index Medicus
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4. Genetic loci associated with C-reactive protein levels and risk of coronary heart disease
by Elliott, Paul and Chambers, John C and Zhang, Weihua and Clarke, Robert and Hopewell, Jemma C and Peden, John F and Erdmann, Jeanette and Braund, Peter and Engert, James C and Bennett, Derrick and Coin, Lachlan and Ashby, Deborah and Tzoulaki, Ioanna and Brown, Ian J and Mt-Isa, Shahrul and McCarthy, Mark I and Peltonen, Leena and Freimer, Nelson B and Farrall, Martin and Ruokonen, Aimo and Hamsten, Anders and Lim, Noha and Froguel, Philippe and Waterworth, Dawn M and Vollenweider, Peter and Waeber, Gerard and Jarvelin, Marjo-Riitta and Mooser, Vincent and Scott, James and Hall, Alistair S and Schunkert, Heribert and Anand, Sonia S and Collins, Rory and Samani, Nilesh J and Watkins, Hugh and Kooner, Jaspal S
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 07/2009, Volume 302, Issue 1, pp. 37 - 48
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Coronary Disease - blood | Genome-Wide Association Study | Meta-Analysis as Topic | Humans | Middle Aged | Risk Factors | Coronary Disease - epidemiology | Genotype | Male | C-Reactive Protein - genetics | C-Reactive Protein - metabolism | Coronary Disease - genetics | Molecular Epidemiology | Adult | Female | Aged | Polymorphism, Single Nucleotide | Proteins | Plasma | Cardiovascular disease
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5. Full Text The genetics of drug efficacy: Opportunities and challenges
by Nelson, Matthew R and Johnson, Toby and Warren, Liling and Hughes, Arlene R and Chissoe, Stephanie L and Xu, Chun-Fang and Waterworth, Dawn M
Nature reviews. Genetics, ISSN 1471-0056, 04/2016, Volume 17, Issue 4, pp. 197 - 206
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Biomarkers, Pharmacological - analysis | Pharmacogenetics - trends | Humans | Drug Discovery - trends | Precision Medicine - trends | Genotype | Treatment Outcome | Drug metabolism | Genetic aspects | Identification and classification | Index Medicus
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6. Full Text The epigenetic signature of systemic insulin resistance in obese women
by Arner, Peter and Sahlqvist, Anna-Stina and Sinha, Indranil and Xu, Huan and Yao, Xiang and Waterworth, Dawn and Rajpal, Deepak and Loomis, A Katrina and Freudenberg, Johannes M and Johnson, Toby and Thorell, Anders and Näslund, Erik and Ryden, Mikael and Dahlman, Ingrid
Diabetologia, ISSN 0012-186X, 11/2016, Volume 59, Issue 11, pp. 2393 - 2405
Medicine & Public Health | Human Physiology | Metabolic Diseases | DNA methylation | Internal Medicine | Visceral adipose tissue | CpG island | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Leukocytes, Mononuclear - metabolism | Collagen Type V - genetics | Humans | Adipose Tissue, White - metabolism | DNA Methylation - genetics | Receptor-Like Protein Tyrosine Phosphatases, Class 3 - genetics | Signal Transduction - genetics | Intra-Abdominal Fat - metabolism | Obesity - genetics | Epigenesis, Genetic - genetics | Insulin Resistance - physiology | Phosphofructokinase-2 - genetics | Adaptor Proteins, Signal Transducing - genetics | Insulin Resistance - genetics | Adult | Female | Signal Transduction - physiology | Insulin Receptor Substrate Proteins - genetics | Type 2 diabetes | Epigenetic inheritance | Obesity | Genomics | Insulin resistance | Methylation | Gene expression | Index Medicus | Medicin och hälsovetenskap
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7. Full Text Genetic variation in LIN28B is associated with the timing of puberty
by Song, Kijoung and Vollenweider, Peter and Golding, Jean and Northstone, Kate and Mooser, Vincent and Khaw, Kay-Tee and Ness, Andrew R and Luan, Jian'an and McGeehin, Michael A and Glaser, Beate and Brage, Soren and Ong, Ken K and Barroso, Inês and Smith, George Davey and Andersen, Lars B and Gillson, Christopher J and Wong, Andrew and Loos, Ruth J and Li, Shengxu and Waeber, Gerard and Wareham, Nicholas J and Ring, Susan M and Rubin, Carol and Elks, Cathy E and Sims, Matthew A and Kuh, Diana and Waterworth, Dawn M and Bingham, Sheila A and Deloukas, Panagiotis and Strachan, David P and Zhao, Jing Hua and Ekelund, Ulf and Hardy, Rebecca and Marcus, Michele and Luben, Robert
Nature genetics, ISSN 1061-4036, 06/2009, Volume 41, Issue 6, pp. 729 - 733
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Meta-Analysis as Topic | Humans | Breast - growth & development | Male | RNA-Binding Proteins | DNA-Binding Proteins - genetics | Genitalia - growth & development | Mothers | Chromosomes, Human, Pair 6 - genetics | Puberty - genetics | Regression Analysis | Adult | Body Height | Female | Genitalia - physiology | Hair - physiology | MicroRNAs - genetics | Polymorphism, Single Nucleotide | Hair - growth & development | Physiological aspects | Puberty | Genetic aspects | Research | Child development | Genetic variation | Womens health | Genetic research | Regression analysis | Biodiversity | Chromosomes | Children & youth | Index Medicus
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8. Full Text Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes
by Yuan, Xin and Waterworth, Dawn and Perry, John R.B and Lim, Noha and Song, Kijoung and Chambers, John C and Zhang, Weihua and Vollenweider, Peter and Stirnadel, Heide and Johnson, Toby and Bergmann, Sven and Beckmann, Noam D and Li, Yun and Ferrucci, Luigi and Melzer, David and Hernandez, Dena and Singleton, Andrew and Scott, James and Elliott, Paul and Waeber, Gerard and Cardon, Lon and Frayling, Timothy M and Kooner, Jaspal S and Mooser, Vincent
American journal of human genetics, ISSN 0002-9297, 2008, Volume 83, Issue 4, pp. 520 - 528
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | General aspects. Genetic counseling | Medical genetics | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Genetics, Population | Liver - enzymology | gamma-Glutamyltransferase - blood | Humans | Middle Aged | Genotype | Male | Alanine Transaminase - blood | Adult | Female | Aged | Enzymes - blood | Genome, Human | Alkaline Phosphatase - blood | Cohort Studies | Liver diseases | Analysis | Physiological aspects | Genetic aspects | Research | Genetic transcription | Population genetics | Blood plasma | Plasma | Enzymes | Genomics | Liver | Genetic diversity | Ribonucleic acid--RNA | Chromosomes | Index Medicus | Report
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9. Full Text Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis
by Lotta, Luca A and Abbasi, Ali and Sharp, Stephen J and Sahlqvist, Anna-Stina and Waterworth, Dawn and Brosnan, Julia M and Scott, Robert A and Langenberg, Claudia and Wareham, Nicholas J
Diabetes care, ISSN 0149-5992, 11/2015, Volume 38, Issue 11, pp. 2177 - 2187
POPULATION | FASTING PLASMA-GLUCOSE | NORMAL-WEIGHT | INSULIN-RESISTANCE | OVERWEIGHT | CARDIOVASCULAR-DISEASE | FATTY LIVER | BODY-MASS INDEX | COHORT | OBESE INDIVIDUALS | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Body Mass Index | Body Weight | Prognosis | Overweight - epidemiology | Humans | Obesity - epidemiology | Risk | Diabetes Mellitus, Type 2 - epidemiology | Type 2 diabetes | Body mass index | Usage | Analysis | Research | Metabolism | Risk factors | Meta-analysis | Systematic review | Diabetes | Index Medicus
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