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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 22, pp. 2578 - 2589
Abstract Background Approximately 7% of American adults have severe hypercholesterolemia (untreated low-density lipoprotein [LDL] cholesterol ≥190 mg/dl),... 
Cardiovascular | Internal Medicine | coronary artery disease | gene sequencing | genetics | low-density lipoprotein cholesterol | POPULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | MYOCARDIAL-INFARCTION | RANDOMIZED-TRIALS | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | RISK | MUTATION DETECTION RATE | CORONARY-HEART-DISEASE | ASSOCIATION | PARTICIPANTS | Receptors, LDL - genetics | Humans | Middle Aged | Hyperlipoproteinemia Type II - diagnosis | Male | Proprotein Convertase 9 - genetics | Apolipoprotein B-100 - genetics | Case-Control Studies | Genetic Variation | Cholesterol, LDL - blood | Female | Heterozygote | Coronary Artery Disease - epidemiology | Sequence Analysis | Cohort Studies | Hypercholesterolemia - epidemiology | Hyperlipoproteinemia Type II - genetics | Medical colleges | Care and treatment | Low density lipoproteins | Genes | Coronary heart disease | Population genetics | Epidemiology | Blood | Hypercholesterolemia | Analysis and chemistry | Atherosclerosis | Genetic research | Genetic aspects | Diagnosis | Research institutes | Cardiology | Trans fatty acids | Heart attacks | Cardiovascular disease | Lipids | Apolipoproteins | Low density lipoprotein | Cholesterol | Proteins | Studies | Confidence intervals | Consortia | Algorithms | Coronary vessels | Population | Mutation | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
Journal Article
by Webb, Thomas R., PhD and Erdmann, Jeanette, PhD and Stirrups, Kathleen E., PhD and Stitziel, Nathan O., MD, PhD and Masca, Nicholas G.D., PhD and Jansen, Henning, MD and Kanoni, Stavroula, PhD and Nelson, Christopher P., PhD and Ferrario, Paola G., PhD and König, Inke R., PhD and Eicher, John D., PhD and Johnson, Andrew D., PhD and Hamby, Stephen E., PhD and Betsholtz, Christer, PhD and Ruusalepp, Arno, MD, PhD and Franzén, Oscar, PhD and Schadt, Eric E., MD, PhD and Björkegren, Johan L.M., MD, PhD and Weeke, Peter E., MD, PhD and Auer, Paul L., PhD and Schick, Ursula M., PhD and Lu, Yingchang, MD, PhD and Zhang, He, PhD and Dube, Marie-Pierre, PhD and Goel, Anuj, MSc and Farrall, Martin, MD and Peloso, Gina M., PhD and Won, Hong-Hee, PhD and Do, Ron, PhD and van Iperen, Erik, MSc and Kruppa, Jochen, PhD and Mahajan, Anubha, PhD and Scott, Robert A., PhD and Willenborg, Christina, PhD and Braund, Peter S., PhD and van Capelleveen, Julian C., MD and Doney, Alex S.F., MD, PhD and Donnelly, Louise A., PhD and Asselta, Rosanna, PhD and Merlini, Pier A., MD and Duga, Stefano, PhD and Marziliano, Nicola, PhD and Denny, Josh C., MD, MS and Shaffer, Christian, BS and El-Mokhtari, Nour Eddine, MD and Franke, Andre, PhD and Heilmann, Stefanie, PhD and Hengstenberg, Christian, MD and Hoffmann, Per, PhD and Holmen, Oddgeir L., MD and Hveem, Kristian, MD, PhD and Jansson, Jan-Håkan, MD, PhD and Jöckel, Karl-Heinz, PhD and Kessler, Thorsten, MD and Kriebel, Jennifer, PhD and Laugwitz, Karl L., MD and Marouli, Eirini, MSc and Martinelli, Nicola, MD, PhD and McCarthy, Mark I., MD and Van Zuydam, Natalie R., PhD and Meisinger, Christa, MD, MPH and Esko, Tõnu, PhD and Mihailov, Evelin, MSc and Escher, Stefan A., PhD and Alver, Maris, MSc and Moebus, Susanne, PhD and Morris, Andrew D., MD and Virtamo, Jarma, MD, PhD and Nikpay, Majid, PhD and Olivieri, Oliviero, MD and Provost, Sylvie, MSc and AlQarawi, Alaa, BSc and Robertson, Neil R., MSc and Akinsansya, Karen O., PhD and Reilly, Dermot F., PhD and Vogt, Thomas F., PhD and Yin, Wu, PhD and Asselbergs, Folkert W., MD, PhD and Kooperberg, Charles, PhD and Jackson, Rebecca D., MD and Stahl, Eli, PhD and Müller-Nurasyid, Martina, PhD and Strauch, Konstantin, PhD and Varga, Tibor V., PhD and Waldenberger, Melanie, PhD and Zeng, Lingyao, MSc and Chowdhury, Rajiv, MD, PhD and Salomaa, Veikko, MD, PhD and Ford, Ian, PhD and Jukema, J. Wouter, MD, PhD and Amouyel, Philippe, MD, PhD and Kontto, Jukka, MSSc and Nordestgaard, Børge G., MD, DMSc and Ferrières, Jean, MD and Saleheen, Danish, MBBS, PhD and Sattar, Naveed, PhD and Surendran, Praveen, PhD and Wagner, Aline, MD, PhD and Young, Robin, PhD and Howson, Joanna M.M., PhD and ... and Wellcome Trust Case Control and MORGAM Investigators and Myocardial Infarction Genetics and Wellcome Trust Case Control Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 823 - 836
Abstract Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show... 
Cardiovascular | Internal Medicine | expression quantitative trait loci | genetics | genome-wide association | single nucleotide polymorphism | cholesteryl ester transfer protein | SR-BI | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | CETP MASS | SUSCEPTIBILITY | RISK | PHOSPHOLIPASE A | VARIANT | SCAVENGER RECEPTOR | ABDOMINAL AORTIC-ANEURYSM | Genome-Wide Association Study | Gene Frequency | Humans | Coronary Artery Disease - genetics | Female | Male | Coronary Artery Disease - epidemiology | Genetic Pleiotropy | Polymorphism, Single Nucleotide | Genetic Loci | Odds Ratio | Case-Control Studies | Coronary heart disease | Analysis | Genealogy | Cardiovascular disease | Genomes | Metabolism | Gene expression | Blood | Risk factors | Studies | Celiac disease | Lipoproteins | Coronary vessels | Rheumatoid arthritis | Quality control | Calcification | Diabetes | Bioinformatics | Index Medicus | Abridged Index Medicus | LD, linkage disequilibrium | CETP, cholesteryl ester transfer protein | eQTL, expression quantitative trait locus | CAD, coronary artery disease | GWAS, genome-wide association study | BMI, body mass index | SNP, single nucleotide polymorphism | HDL, high-density lipoprotein | LDL, low-density lipoprotein | Original Investigation | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Medical Genetics | Medicinsk genetik | Clinical Medicine | Cardiac and Cardiovascular Systems | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Helgadottir, Anna, MD, PhD and Gretarsdottir, Solveig, PhD and Thorleifsson, Gudmar, PhD and Holm, Hilma, MD and Patel, Riyaz S., MD and Gudnason, Thorarinn, MD, PhD and Jones, Gregory T., PhD and van Rij, Andre M., MD and Eapen, Danny J., MD and Baas, Annette F., PhD and Tregouet, David-Alexandre, PhD and Morange, Pierre-Emmanuel, MD and Emmerich, Joseph, MD, PhD and Lindblad, Bengt, MD, PhD and Gottsäter, Anders, MD, PhD and Kiemeny, Lambertus A., PhD and Lindholt, Jes S., MD, PhD and Sakalihasan, Natzi, MD, PhD and Ferrell, Robert E., PhD and Carey, David J., PhD and Elmore, James R., MD and Tsao, Philip S., PhD and Grarup, Niels, MD, PhD and Jørgensen, Torben, MD, DMSci and Witte, Daniel R., MD, PhD and Hansen, Torben, MD, PhD and Pedersen, Oluf, MD, DMSci and Pola, Roberto, MD, PhD and Gaetani, Eleonora, MD and Magnadottir, Hulda B., MD and Wijmenga, Cisca, PhD and Tromp, Gerard, PhD and Ronkainen, Antti, MD, PhD and Ruigrok, Ynte M., MD and Blankensteijn, Jan D and Mueller, Thomas, MD and Wells, Philip S., MD and Corral, Javier, PhD and Soria, Jose Manuel, PhD and Souto, Juan Carlos, MD, PhD and Peden, John F., PhD and Jalilzadeh, Shapour, MD, PhD and Mayosi, Bongani M., DPhil and Keavney, Bernard, MD and Strawbridge, Rona J., PhD and Sabater-Lleal, Maria, PhD and Gertow, Karl, PhD and Baldassarre, Damiano, PhD and Nyyssönen, Kristiina, PhD and Rauramaa, Rainer, MD, PhD and Smit, Andries J., MD, PhD and Mannarino, Elmo, MD and Giral, Philippe, MD and Tremoli, Elena, PhD and de Faire, Ulf, MD, PhD and Humphries, Steve E., PhD and Hamsten, Anders, MD, PhD and Haraldsdottir, Vilhelmina, MD and Olafsson, Isleifur, MD, PhD and Magnusson, Magnus K., MD and Samani, Nilesh J., MD and Levey, Allan I., MD, PhD and Markus, Hugh S., MD and Kostulas, Konstantinos, MD, PhD and Dichgans, Martin, MD and Berger, Klaus, MD and Kuhlenbäumer, Gregor, MD and Ringelstein, E. Bernd, MD and Stoll, Monika, PhD and Seedorf, Udo, PhD and Rothwell, Peter M., MD, PhD and Powell, Janet T., MD and Kuivaniemi, Helena, MD, PhD and Onundarson, Pall T., MD and Valdimarsson, Einar, MD and Matthiasson, Stefan E., MD, PhD and Gudbjartsson, Daniel F., PhD and Thorgeirsson, Guðmundur, MD, PhD and Quyyumi, Arshed A., MD and Watkins, Hugh, MD, PhD and Farrall, Martin, MD and Thorsteinsdottir, Unnur, PhD and Stefansson, Kari, MD, PhD and Lund University and Vascular Diseases - Clinical Research and Vaskulära sjukdomar - kliniska studier and Lunds universitet
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2012, Volume 60, Issue 8, pp. 722 - 729
Objectives The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene ( LPA ) on vascular diseases with different... 
Cardiovascular | Internal Medicine | atherosclerosis | genetic | association | thrombosis | lipoprotein(a) | INTIMA-MEDIA THICKNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | METAANALYSIS | MYOCARDIAL-INFARCTION | VASCULAR-DISEASE | WOMEN | PERIPHERAL ARTERIAL-DISEASE | ISCHEMIC-STROKE | SEVERITY | Severity of Illness Index | Myocardial Infarction - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Apolipoproteins A - genetics | Angiography | Carotid Intima-Media Thickness | Intracranial Aneurysm - genetics | Atherosclerosis - genetics | Humans | Risk Factors | Brain Ischemia - genetics | African Americans - genetics | Linear Models | Logistic Models | Aortic Aneurysm, Abdominal - genetics | Stroke - genetics | Venous Thromboembolism - genetics | Peripheral Arterial Disease - genetics | Age of Onset | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Odds Ratio | Medical colleges | Neurosciences | Stock options | Genes | Aneurysms | Coronary heart disease | Biometry | Lipoprotein A | Anopheles | Atherosclerosis | Medical genetics | Genetic research | Genetic aspects | Diabetes | Thromboembolism | Cardiology | Public health | Dementia | Stroke | Medical imaging | Values | Cardiovascular disease | Apolipoproteins | Thrombosis | Studies | Confidence intervals | Coronary vessels | Blood pressure | Drug therapy | Age | Methods | Index Medicus | Abridged Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 12/2016, Volume 68, Issue 25, pp. 2761 - 2772
Journal Article
American Heart Journal, ISSN 0002-8703, 2015, Volume 169, Issue 5, pp. 605 - 612
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 61, Issue 9, pp. 957 - 970
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 904 - 906
  Participants ages >6 years underwent anatomical and functional aortic cardiac magnetic resonance imaging (n = 117) as described (1), including valve... 
Cardiovascular | Internal Medicine | DILATION | CARDIAC & CARDIOVASCULAR SYSTEMS | Heart valve diseases | Research institutes | Aneurysms | Coronary vessels | Index Medicus | Abridged Index Medicus
Journal Article