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Hepatology, ISSN 0270-9139, 06/2018, Volume 67, Issue 6, pp. 2481 - 2482
Journal Article
Hepatology, ISSN 0270-9139, 06/2018, Volume 67, Issue 6, pp. 2481 - 2482
Journal Article
Hepatology, ISSN 0270-9139, 06/2018, Volume 67, Issue 6, pp. 2481 - 2482
Journal Article
Hepatology, ISSN 0270-9139, 06/2018, Volume 67, Issue 6, pp. 2481 - 2482
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Clinical and Translational Science, ISSN 1752-8054, 03/2019, Volume 12, Issue 2, pp. 122 - 129
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Toxicological sciences : an official journal of the Society of Toxicology, ISSN 1096-6080, 07/2019, Volume 171, Issue 2, pp. 431 - 442
Drug-induced liver injury (DILI) remains a major challenge in drug development. Although numerous mechanisms for DILI have been identified, few studies have... 
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2019, Volume 14, Issue 1, p. e0208958
Hepatic fibrosis develops from a series of complex interactions among resident and recruited cells making it a challenge to replicate using standard in vitro... 
Bioengineering | Cell culture | Liver | Kupffer cells | Collagens | Homeostasis | Macrophages | Time dependence | Toxicology | Rodents | Methotrexate | Drug therapy | Product safety | Automation | Cytokines | Research & development--R&D | Tissue engineering | Exposure | Gene expression | Injury prevention | Three dimensional printing | MicroRNAs | Pharmacy | Collagen | Fibrosis | Research & development | R&D
Journal Article
by Winkler, Thomas W and Justice, Anne E and Graff, Mariaelisa and Barata, Llilda and Feitosa, Mary F and Chu, Su and Czajkowski, Jacek and Esko, Tõnu and Fall, Tove and Kilpeläinen, Tuomas O and Lu, Yingchang and Mägi, Reedik and Mihailov, Evelin and Pers, Tune H and Rüeger, Sina and Teumer, Alexander and Ehret, Georg B and Ferreira, Teresa and Heard-Costa, Nancy L and Karjalainen, Juha and Lagou, Vasiliki and Mahajan, Anubha and Neinast, Michael D and Prokopenko, Inga and Simino, Jeannette and Teslovich, Tanya M and Jansen, Rick and Westra, Harm-Jan and White, Charles C and Absher, Devin and Ahluwalia, Tarunveer S and Ahmad, Shafqat and Albrecht, Eva and Alves, Alexessander Couto and Bragg-Gresham, Jennifer L and de Craen, Anton J. M and Bis, Joshua C and Bonnefond, Amélie and Boucher, Gabrielle and Cadby, Gemma and Cheng, Yu-Ching and Chiang, Charleston W. K and Delgado, Graciela and Demirkan, Ayse and Dueker, Nicole and Eklund, Niina and Eiriksdottir, Gudny and Eriksson, Joel and Feenstra, Bjarke and Fischer, Krista and Frau, Francesca and Galesloot, Tessel E and Geller, Frank and Goel, Anuj and Gorski, Mathias and Grammer, Tanja B and Gustafsson, Stefan and Haitjema, Saskia and Hottenga, Jouke-Jan and Huffman, Jennifer E and Jackson, Anne U and Jacobs, Kevin B and Johansson, Åsa and Kaakinen, Marika and Kleber, Marcus E and Lahti, Jari and Mateo Leach, Irene and Lehne, Benjamin and Liu, Youfang and Lo, Ken Sin and Lorentzon, Mattias and Luan, Jian'an and Madden, Pamela A. F and Mangino, Massimo and McKnight, Barbara and Medina-Gomez, Carolina and Monda, Keri L and Montasser, May E and Müller, Gabriele and Müller-Nurasyid, Martina and Nolte, Ilja M and Panoutsopoulou, Kalliope and Pascoe, Laura and Paternoster, Lavinia and Rayner, Nigel W and Renström, Frida and Rizzi, Federica and Rose, Lynda M and Ryan, Kathy A and Salo, Perttu and Sanna, Serena and Scharnagl, Hubert and Shi, Jianxin and Smith, Albert Vernon and Southam, Lorraine and Stančáková, Alena and Steinthorsdottir, Valgerdur and Strawbridge, Rona J and Sung, Yun Ju and Tachmazidou, Ioanna and ... and DIAGRAM Consortium and CHARGE Consortium and GLGC Consortium and MAGIC Consortium and ICBP Consortium and Global-BPGen Consortium
PLoS genetics, ISSN 1553-7390, 2015, Volume 11, Issue 10, pp. 1 - 42
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio... 
LIFE-COURSE | BIOLOGICAL PATHWAYS | NATURAL MENOPAUSE | MASS INDEX | COMMON SNPS | GENETICS & HEREDITY | PERIPHERAL-BLOOD | WEIGHT-GAIN | LOCI | FAT DISTRIBUTION | SELF-REPORTED HEIGHT | Body Mass Index | Genetic Predisposition to Disease | Genome-Wide Association Study | Age Factors | Humans | Middle Aged | European Continental Ancestry Group | Male | Chromosome Mapping | Sex Characteristics | Adult | Female | Aged | Body Size - genetics | Polymorphism, Single Nucleotide | Waist-Hip Ratio | Genetic research | Dimorphism (Biology) | Research | Single nucleotide polymorphisms | Samfunnsmedisin, sosialmedisin: 801 | Community medicine, Social medicine: 801 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Life Sciences | Genetics | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | HNE Voeding en Gezondheid in de Levenscyclus | Wereldvoeding | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | HNE Nutrition and Health over the Lifecourse | Women | Medical research | Funding | Health care policy | Biology | Genomes | Studies | Consortia | Body mass index | Mens health | Councils | Older people | Gene loci | Adults | Diabetes | Age | Metabolic disorders
Journal Article
Toxicological sciences : an official journal of the Society of Toxicology, ISSN 1096-6080, 09/2019
Idelalisib is a phosphatidylinositol 3-kinase inhibitor highly selective for the delta isoform that has shown good efficacy in treating chronic lymphocytic... 
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 03/2019, Volume 105, Issue 3, pp. 746 - 753
It is not currently possible to rapidly estimate the extent of hepatocyte loss during drug‐induced liver injury (DILI). We used a proprietary mechanistic model... 
BIOMARKERS | MECHANISTIC MODEL | PHARMACOLOGY & PHARMACY | TOXICITY | DILISYM(R) | OVERDOSE
Journal Article
Drug Safety, ISSN 0114-5916, 3/2011, Volume 34, Issue 3, pp. 243 - 252
Journal Article