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Annals of Internal Medicine, ISSN 0003-4819, 2017, Volume 166, Issue 6, pp. JC30 - JC30
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 01/2018, Volume 2018, Issue 1, pp. 38 - 40
A useful feature of therapeutic antibodies is the ability to kill the cells to which they bind. Antibodies are capable of mediating cell killing in a variety... 
Staining and Labeling - methods | Flow Cytometry - methods | Propidium - analysis | Annexin A5 - analysis | Eukaryotic Cells - physiology | Apoptosis | High-Throughput Screening Assays - methods
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 02/2018, Issue 2
A useful feature of therapeutic antibodies is the ability to kill the cells to which they bind. Antibodies are capable of mediating cell killing in a variety... 
Flow cytometry | Immunoglobulins | Cell death | Tumor cells | Toxicity | Immunoglobulin G | Antibodies | Cytotoxicity | Membrane attack complex | Complement | Assaying | Apoptosis
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 01/2018, Issue 1, p. 34
This simple protocol tests antibody binding to target antigens on the surface of cells. This assay is powerful because negative controls are built into each... 
Binding | Antigens | Screening | Phages | Cell lines | Assaying | Beads | Enzyme-linked immunosorbent assay
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 02/2018, Issue 2
A useful feature of therapeutic antibodies is the ability to kill the cells to which they bind. Antibodies are capable of mediating cell killing in a variety... 
Flow cytometry | Immunoglobulins | Toxicity | Immunoglobulin G | Antibodies | Effector cells | Cytotoxicity | Lymphocytes T | Complement | Cell surface | Fc receptors | Receptors | Lymphocytes | Endopeptidase | γ-Interferon | Serine proteinase | Interferon | Natural killer cells | Perforin | Immune system | Apoptosis
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 01/2018, Issue 1
Because molecular targets addressable with antibody therapeutics are present on the surface of cells or in circulation, they are ideal for screening by cell-... 
Multiplexing | Flow cytometry | Screening | Technology | Beads | Content analysis
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 01/2018, Issue 1
A useful feature of therapeutic antibodies is the ability to kill the cells to which they bind. Antibodies are capable of mediating cell killing in a variety... 
Flow cytometry | Iodides | Calcium | Toxicity | Serine | Antibodies | Staining | Cytotoxicity | Propidium iodide | Complement | Assaying | Flow | Ethylenediaminetetraacetic acids | Cell death | Dependence | Calcium buffering | Annexin V | Binding sites | Apoptosis
Journal Article
European heart journal cardiovascular Imaging, ISSN 2047-2404, 07/2019, Volume 20, Issue 9, pp. 979 - 987
Longitudinal change in left atrial (LA) structure and function could be helpful in predicting risk for incident atrial fibrillation (AF). We used cardiac... 
atrial fibrillation | left atrium | Original | Editor's Choice
Journal Article
by Do, Ron and Stitziel, Nathan O and Won, Hong-Hee and Jørgensen, Anders Berg and Duga, Stefano and Angelica Merlini, Pier and Kiezun, Adam and Farrall, Martin and Goel, Anuj and Zuk, Or and Guella, Illaria and Asselta, Rosanna and Lange, Leslie A and Peloso, Gina M and Auer, Paul L and Girelli, Domenico and Martinelli, Nicola and Farlow, Deborah N and DePristo, Mark A and Roberts, Robert and Stewart, Alexander F. R and Saleheen, Danish and Danesh, John and Epstein, Stephen E and Sivapalaratnam, Suthesh and Hovingh, G. Kees and Kastelein, John J and Samani, Nilesh J and Schunkert, Heribert and Erdmann, Jeanette and Shah, Svati H and Kraus, William E and Davies, Robert and Nikpay, Majid and Johansen, Christopher T and Wang, Jian and Hegele, Robert A and Hechter, Eliana and Marz, Winfried and Kleber, Marcus E and Huang, Jie and Johnson, Anew D and Li, Mingyao and Burke, Greg L and Gross, Myron and Liu, Yongmei and Assimes, Themistocles L and Heiss, Gerardo and Lange, Ethan M and Folsom, Aaron R and Taylor, Herman A and Olivieri, Oliviero and Hamsten, Anders and Clarke, Robert and Reilly, Dermot F and Yin, Wu and Rivas, Manuel A and Donnelly, Peter and Rossouw, Jacques E and Psaty, Bruce M and Herrington, David M and Wilson, James G and Rich, Stephen S and Bamshad, Michael J and Tracy, Russell P and Cupples, L. Aienne and Rader, Daniel J and Reilly, Muredach P and Spertus, John A and Cresci, Sharon and Hartiala, Jaana and Tang, W. H. Wilson and Hazen, Stanley L and Allayee, Hooman and Reiner, Alex P and Carlson, Christopher S and Kooperberg, Charles and Jackson, Rebecca D and Boerwinkle, Eric and Lander, Eric S and Schwartz, Stephen M and Siscovick, David S and McPherson, Ruth and Tybjaerg-Hansen, Anne and Abecasis, Goncalo R and Watkins, Hugh and Nickerson, Deborah A and Ardissino, Diego and Sunyaev, Shamil R and O'Donnell, Christopher J and Altshuler, David and Gabriel, Stacey and Kathiresan, Sekar and Gabriel, Stacey B and Altshuler, David M and Abecasis, Gonçalo R and Daly, Mark J and de Bakker, Paul I. W and Fennell, Tim and Garimella, Kiran and ... and NHLBI Exome Sequencing Project
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7537, pp. 102 - +
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2017, Volume 376, Issue 7, pp. 617 - 628
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 01/2018, Volume 2018, Issue 1, pp. 7 - 12
Because molecular targets addressable with antibody therapeutics are present on the surface of cells or in circulation, they are ideal for screening by cell-... 
Staining and Labeling - methods | Flow Cytometry - methods | Animals | High-Throughput Screening Assays | Antibodies - metabolism | Antigens - analysis | Humans | Protein Binding | Immunologic Factors - metabolism
Journal Article
by Lange, Leslie A and Lange, Ethan M and Lange, Christoph and Hu, Youna and Zhang, Qunyuan and Zhang, Ji and Zhang, He and Xue, Chenyi and Schmidt, Ellen M and Tang, Hua and Tang, Zheng-Zheng and Bizon, Chris and Smith, Nicholas L and Smith, Joshua D and Smith, Albert V and Turner, Emily H and Jun, Goo and Kang, Hyun Min and Peloso, Gina and Auer, Paul L and Auer, Paul and Li, Kuo-ping and Li, Mingyao and Li, Yun and Li, Bingshan and Li, Dalin and Flannick, Jason and Fuchsberger, Christian and Gaulton, Kyle and Lindgren, Cecilia and Locke, Adam and Manning, Alisa and Sim, Xueling and Rivas, Manuel A and Holmen, Oddgeir L and Gottesman, Omri and Lu, Yingchang and Ruderfer, Douglas and Stahl, Eli A and Duan, Qing and Durda, Peter and Durda, J. Peter and Jiao, Shuo and Isaacs, Aaron and Hofman, Albert and Bis, Joshua C and Bis, Joshua and Correa, Adolfo and Griswold, Michael E and Jakobsdottir, Johanna and Schreiner, Pamela and Schreiner, Pamela J and Feitosa, Mary F and Huffman, Jennifer E and Crosby, Jacy and Wassel, Chrstina L and Wassel, Christina L and Do, Ron and Franceschini, Nora and Martin, Lisa and Martin, Lisa W and Martin, Thomas R and Robinson, Jennifer G and Assimes, Themistocles L and Crosslin, David R and Rosenthal, Elisabeth A and Tsai, Michael Y and Tsai, Michael and Rieder, Mark J and Farlow, Deborah N and Folsom, Aaron R and Lumley, Thomas and Fox, Ervin R and Fox, Caroline S and Fox, P. Keolu and Fox, Ervin and Carlson, Christopher S and Peters, Ulrike and Jackson, Rebecca D and Jackson, Rebecca and van Duijn, Cornelia M and Uitterlinden, André G and Levy, Daniel and Rotter, Jerome I and Taylor, Herman A and Taylor, Kira C and Taylor, Kent and Gudnason, Vilmundur and Siscovick, David S and Fornage, Myriam and Borecki, Ingrid B and Hayward, Caroline and Rudan, Igor and Chen, Wei-Min and Chen, Y. Eugene and Chen, Donna T and Chen, Ida Y and Bottinger, Erwin P and Loos, Ruth J.F and Sætrom, Pål and ... and NHLBI Grand Opportunity Exome Sequ and NHLBI Grand Opportunity Exome Sequencing Project and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 233 - 245
Journal Article