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Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 5107 - 5107
MDS and AML are generally not considered curable in older patients (pts) outside of allogeneic transplant. Hypomethylating agents (HMAs) have clinical activity... 
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 09/2019, Volume 37, Issue 27_suppl, pp. 216 - 216
216 Background: The University of Miami’s Phase I Program is South Florida’s only academic Phase I center dedicated to drug development for cancer patients. On... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 4037 - 4037
Abstract Introduction The vascular disrupting agent OXi4503, induces apoptosis in malignant myeloblasts, removes their endothelial cell protection, and... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5527 - 5527
Abstract Introduction: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal myeloid disorders, affecting primarily older individuals and... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5973 - 5973
Abstract Purpose: To examine the incidence and frequency of neurological complications secondary to intrathecal chemotherapy. Introduction: Intrathecal (IT)... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 460 - 460
Abstract Acute Promyelocytic Leukemia (APL) is a cytogenetically unique subtype of acute myeloid leukemia (AML), characterized by the presence of the... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 3786 - 3786
Abstract The histone methyltransferase Enhancer of Zeste Homologue 2 (EZH2), a component of the polycomb group complex, is critical for normal hematopoietic... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 1004 - 1004
Abstract Introduction Early bone marrow (BM) evaluation (during aplasia or at “day 14” (D14)) in patients with AML undergoing conventional induction therapy... 
Journal Article
by Tyner, Jeffrey W and Tognon, Cristina E and Bottomly, Daniel and Wilmot, Beth and Kurtz, Stephen E and Savage, Samantha L and Long, Nicola and Schultz, Anna Reister and Traer, Elie and Abel, Melissa and Agarwal, Anupriya and Blucher, Aurora and Borate, Uma and Bryant, Jade and Burke, Russell and Carlos, Amy and Carpenter, Richie and Carroll, Joseph and Chang, Bill H and Coblentz, Cody and d’Almeida, Amanda and Cook, Rachel and Danilov, Alexey and Dao, Kim-Hien T and Degnin, Michie and Devine, Deirdre and Dibb, James and Edwards, David K and Eide, Christopher A and English, Isabel and Glover, Jason and Henson, Rachel and Ho, Hibery and Jemal, Abdusebur and Johnson, Kara and Johnson, Ryan and Junio, Brian and Kaempf, Andy and Leonard, Jessica and Lin, Chenwei and Liu, Selina Qiuying and Lo, Pierrette and Loriaux, Marc M and Luty, Samuel and Macey, Tara and MacManiman, Jason and Martinez, Jacqueline and Mori, Motomi and Nelson, Dylan and Nichols, Ceilidh and Peters, Jill and Ramsdill, Justin and Rofelty, Angela and Schuff, Robert and Searles, Robert and Segerdell, Erik and Smith, Rebecca L and Spurgeon, Stephen E and Sweeney, Tyler and Thapa, Aashis and Visser, Corinne and Wagner, Jake and Watanabe-Smith, Kevin and Werth, Kristen and Wolf, Joelle and White, Libbey and Yates, Amy and Zhang, Haijiao and Cogle, Christopher R and Collins, Robert H and Connolly, Denise C and Deininger, Michael W and Drusbosky, Leylah and Hourigan, Christopher S and Jordan, Craig T and Kropf, Patricia and Lin, Tara L and Martinez, Micaela E and Medeiros, Bruno C and Pallapati, Rachel R and Pollyea, Daniel A and Swords, Ronan T and Watts, Justin M and Weir, Scott J and Wiest, David L and Winters, Ryan M and McWeeney, Shannon K and Druker, Brian J
Nature, ISSN 0028-0836, 10/2018, Volume 562, Issue 7728, pp. 526 - 531
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5279 - 5279
Abstract Background: One of the more important prognostic factors used to predict the outcome in acute myeloid leukemia (AML) is the persistence of leukemic... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4157 - 4157
Background: Bosutinib is approved at a starting dose of 500 mg once daily (QD) in patients with Philadelphia chromosome-positive chronic myeloid leukemia (CML)... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 5159 - 5159
BACKGROUND: Acute myeloid leukemia (AML) is the most common acute leukemia amongst adults which requires multiple phases and combinations of chemotherapeutic... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 1639 - 1639
Background: Some patients receiving a tyrosine kinase inhibitor (TKI) for chronic phase (CP) Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2656 - 2656
Background Protein arginine methyltransferase 5 (PRMT5) is the primary enzyme responsible for symmetric arginine dimethylation of multiple proteins that impact... 
Journal Article