1997, Seminars in cancer biology, Volume 8, issue 1., 59
Book
1996, Cancer, clinical science in practice., ISBN 9780521460675, ix, 428
Book
Nature Reviews Urology, ISSN 1759-4812, 08/2012, Volume 9, Issue 8, pp. 418 - 428
Journal Article
2007, ISBN 9781846284649, xii, 275
Urological oncology constitutes 20 per cent of all malignant disease, and includes renal, bladder, prostate and testicular cancer. This is an area of medical...
Genitourinary organs | Cancer | Clinical & internal medicine | Treatment | Medicine & Public Health | Urology/Andrology | Oncology
Genitourinary organs | Cancer | Clinical & internal medicine | Treatment | Medicine & Public Health | Urology/Andrology | Oncology
Book
2013, ISBN 9781447145219
Web Resource
Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 10, pp. 925 - 926
Journal Article
1987, ISBN 9780713145274, viii, 168
Book
2012, ISBN 9780857298959
Web Resource
EMBO reports, ISSN 1469-221X, 04/2016, Volume 17, Issue 4, pp. 570 - 584
Here, we show that miR‐515‐5p inhibits cancer cell migration and metastasis. RNA‐seq analyses of both oestrogen receptor receptor‐positive and...
lung cancer | microRNAs | breast cancer | microtubule affinity‐regulating kinase 4 | miR‐515‐5p | MIR-515-5p | microtubule affinity-regulating kinase 4 | NETWORK | METASTASIS | SIGNATURES | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | miR-515-5p | CELL BIOLOGY | BIOMARKERS | LUNG-CANCER | GENE | EXPRESSION | PROGRESSION | Lung Neoplasms - genetics | A549 Cells | Cell Proliferation - genetics | Neoplasm Invasiveness | Down-Regulation | Humans | Gene Expression Regulation, Neoplastic | Protein-Serine-Threonine Kinases - genetics | Neoplasm Metastasis | Animals | Breast Neoplasms - genetics | MCF-7 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Line, Tumor | Female | Mice | MicroRNAs - genetics | RNA, Messenger | Apoptosis | Cell Movement | Metastasis | Cancer | Cell adhesion & migration | Cell Adhesion, Polarity & Cytoskeleton | RNA Biology
lung cancer | microRNAs | breast cancer | microtubule affinity‐regulating kinase 4 | miR‐515‐5p | MIR-515-5p | microtubule affinity-regulating kinase 4 | NETWORK | METASTASIS | SIGNATURES | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | miR-515-5p | CELL BIOLOGY | BIOMARKERS | LUNG-CANCER | GENE | EXPRESSION | PROGRESSION | Lung Neoplasms - genetics | A549 Cells | Cell Proliferation - genetics | Neoplasm Invasiveness | Down-Regulation | Humans | Gene Expression Regulation, Neoplastic | Protein-Serine-Threonine Kinases - genetics | Neoplasm Metastasis | Animals | Breast Neoplasms - genetics | MCF-7 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Line, Tumor | Female | Mice | MicroRNAs - genetics | RNA, Messenger | Apoptosis | Cell Movement | Metastasis | Cancer | Cell adhesion & migration | Cell Adhesion, Polarity & Cytoskeleton | RNA Biology
Journal Article
Nature Reviews Clinical Oncology, ISSN 1759-4774, 06/2011, Volume 8, Issue 6, pp. 357 - 368
Metastatic bone disease (MBD) in advanced-stage cancer increases the risk of intractable bone pain, pathological skeletal fracture, spinal-cord compression and...
AMINO-TERMINAL FRAGMENT | BREAST-CANCER | ZOLEDRONIC ACID | GROWTH-FACTOR-BETA | MITOXANTRONE PLUS PREDNISONE | ANDROGEN-DEPRIVATION | ONCOLOGY | RANDOMIZED PHASE-II | CATHEPSIN-K | DOUBLE-BLIND | OSTEOCLAST DIFFERENTIATION | Prostatic Neoplasms - pathology | Animals | Bone Neoplasms - therapy | Humans | Bone Neoplasms - secondary | Male | Disease Models, Animal | Prostatic Neoplasms - therapy | Complications and side effects | Chemotherapy | Bone cancer | Care and treatment | Research | Prostate cancer | Health aspects | Risk factors | Cancer
AMINO-TERMINAL FRAGMENT | BREAST-CANCER | ZOLEDRONIC ACID | GROWTH-FACTOR-BETA | MITOXANTRONE PLUS PREDNISONE | ANDROGEN-DEPRIVATION | ONCOLOGY | RANDOMIZED PHASE-II | CATHEPSIN-K | DOUBLE-BLIND | OSTEOCLAST DIFFERENTIATION | Prostatic Neoplasms - pathology | Animals | Bone Neoplasms - therapy | Humans | Bone Neoplasms - secondary | Male | Disease Models, Animal | Prostatic Neoplasms - therapy | Complications and side effects | Chemotherapy | Bone cancer | Care and treatment | Research | Prostate cancer | Health aspects | Risk factors | Cancer
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 2015, Volume 149, Issue 1, pp. 59 - 67
Obesity is a known risk factor for breast cancer. We have recently identified that adipokine leptin regulates the expression of a proto-oncogenic enzyme...
Obesity | Breast cancer | Adipokine | IL-6 | Sphingosine | STAT3 | CELLS | CONSTITUTIVE ACTIVATION | HIGH EXPRESSION | EPITHELIAL-MESENCHYMAL TRANSITION | INHIBITION | ONCOLOGY | PATHWAY | RESISTANCE | OB-R | SIGNAL TRANSDUCER | Phosphorylation | Transcriptional Activation - genetics | Receptors, Estrogen - genetics | Interleukin-6 - genetics | Receptors, Leptin - genetics | Signal Transduction | Humans | Gene Expression Regulation, Neoplastic | Phosphotransferases (Alcohol Group Acceptor) - genetics | Leptin - genetics | Lymphatic Metastasis | Gene Knockdown Techniques | STAT3 Transcription Factor - biosynthesis | Breast Neoplasms - genetics | Cytokine Receptor gp130 - biosynthesis | Cell Line, Tumor | Interleukin-6 - biosynthesis | Female | STAT3 Transcription Factor - genetics | Phosphotransferases (Alcohol Group Acceptor) - biosynthesis | Enzymes | RNA | Leptin | Estrogen | Genetic aspects | Gene expression | Health aspects | Enzyme-linked immunosorbent assay | Cancer
Obesity | Breast cancer | Adipokine | IL-6 | Sphingosine | STAT3 | CELLS | CONSTITUTIVE ACTIVATION | HIGH EXPRESSION | EPITHELIAL-MESENCHYMAL TRANSITION | INHIBITION | ONCOLOGY | PATHWAY | RESISTANCE | OB-R | SIGNAL TRANSDUCER | Phosphorylation | Transcriptional Activation - genetics | Receptors, Estrogen - genetics | Interleukin-6 - genetics | Receptors, Leptin - genetics | Signal Transduction | Humans | Gene Expression Regulation, Neoplastic | Phosphotransferases (Alcohol Group Acceptor) - genetics | Leptin - genetics | Lymphatic Metastasis | Gene Knockdown Techniques | STAT3 Transcription Factor - biosynthesis | Breast Neoplasms - genetics | Cytokine Receptor gp130 - biosynthesis | Cell Line, Tumor | Interleukin-6 - biosynthesis | Female | STAT3 Transcription Factor - genetics | Phosphotransferases (Alcohol Group Acceptor) - biosynthesis | Enzymes | RNA | Leptin | Estrogen | Genetic aspects | Gene expression | Health aspects | Enzyme-linked immunosorbent assay | Cancer
Journal Article
Respiratory Medicine Case Reports, ISSN 2213-0071, 2019, Volume 28, p. 100895
Most recurrences of solitary fibrous tumor of the pleura (SFTP) occur within 2 years. Here we report a rare case of bilateral recurrence in a 61 year old...
Case Report
Case Report
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2009, Volume 106, Issue 37, pp. 15732 - 15737
Following estrogenic activation, the estrogen receptor-α (ERα) directly regulates the transcription of target genes via DNA binding. MicroRNAs (miRNAs)...
Up regulation | MicroRNA | RNA | Estrogens | Genes | Cell lines | Hormonal regulation | Breast cancer | Gene expression regulation | Tumors | AIB1 | Autoregulatory feedback loop | Primary transcript | Processing | POSTTRANSCRIPTIONAL REGULATION | HUMAN-BREAST-CANCER | MULTIDISCIPLINARY SCIENCES | autoregulatory feedback loop | C-MYC | CELL-PROLIFERATION | MATURATION | FEEDBACK LOOP | MESSENGER-RNA | BIOGENESIS | REPRESSION | primary transcript | processing | EXPRESSION | Transcription, Genetic - drug effects | Ribonuclease III - genetics | Ribonuclease III - metabolism | RNA Processing, Post-Transcriptional | Humans | MicroRNAs - metabolism | RNA, Neoplasm - metabolism | Breast Neoplasms - metabolism | Up-Regulation - drug effects | Breast Neoplasms - genetics | Estrogen Receptor alpha - genetics | Cell Line, Tumor | RNA, Neoplasm - genetics | Estrogen Receptor alpha - metabolism | Female | MicroRNAs - genetics | 3' Untranslated Regions | Estradiol - pharmacology | Biological Sciences
Up regulation | MicroRNA | RNA | Estrogens | Genes | Cell lines | Hormonal regulation | Breast cancer | Gene expression regulation | Tumors | AIB1 | Autoregulatory feedback loop | Primary transcript | Processing | POSTTRANSCRIPTIONAL REGULATION | HUMAN-BREAST-CANCER | MULTIDISCIPLINARY SCIENCES | autoregulatory feedback loop | C-MYC | CELL-PROLIFERATION | MATURATION | FEEDBACK LOOP | MESSENGER-RNA | BIOGENESIS | REPRESSION | primary transcript | processing | EXPRESSION | Transcription, Genetic - drug effects | Ribonuclease III - genetics | Ribonuclease III - metabolism | RNA Processing, Post-Transcriptional | Humans | MicroRNAs - metabolism | RNA, Neoplasm - metabolism | Breast Neoplasms - metabolism | Up-Regulation - drug effects | Breast Neoplasms - genetics | Estrogen Receptor alpha - genetics | Cell Line, Tumor | RNA, Neoplasm - genetics | Estrogen Receptor alpha - metabolism | Female | MicroRNAs - genetics | 3' Untranslated Regions | Estradiol - pharmacology | Biological Sciences
Journal Article
08/2013, ISBN 9781447145219, 199
'MacLeod's Introduction to Medicine: A Doctor's Memoir' is a collection of stories that gives the reader an insight into the humorous side of a doctor's life....
Medicine
Medicine
eBook
NATURE REVIEWS UROLOGY, ISSN 1759-4812, 08/2012, Volume 9, Issue 8, pp. 418 - 428
The Wnts are secreted cysteine-rich glycoproteins that have important roles in the developing embryo as well as in tissue homeostasis in adults. Dysregulation...
SMALL-MOLECULE INHIBITORS | EPITHELIAL BRANCHING MORPHOGENESIS | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | ANDROGEN RECEPTOR-ACTIVITY | CANONICAL WNT PATHWAY | NUCLEAR BETA-CATENIN | FRIZZLED-RELATED PROTEIN-1 | E-CADHERIN | CELL-ADHESION PROTEINS | TUMOR-GROWTH | Prostatic Neoplasms - metabolism | Adenocarcinoma - metabolism | Animals | Cell Proliferation | Humans | Receptors, Androgen - metabolism | Epithelial-Mesenchymal Transition | Male | Cell Differentiation | T Cell Transcription Factor 1 - metabolism | Lymphoid Enhancer-Binding Factor 1 - metabolism | Wnt Signaling Pathway
SMALL-MOLECULE INHIBITORS | EPITHELIAL BRANCHING MORPHOGENESIS | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | ANDROGEN RECEPTOR-ACTIVITY | CANONICAL WNT PATHWAY | NUCLEAR BETA-CATENIN | FRIZZLED-RELATED PROTEIN-1 | E-CADHERIN | CELL-ADHESION PROTEINS | TUMOR-GROWTH | Prostatic Neoplasms - metabolism | Adenocarcinoma - metabolism | Animals | Cell Proliferation | Humans | Receptors, Androgen - metabolism | Epithelial-Mesenchymal Transition | Male | Cell Differentiation | T Cell Transcription Factor 1 - metabolism | Lymphoid Enhancer-Binding Factor 1 - metabolism | Wnt Signaling Pathway
Journal Article
Molecular Cancer, ISSN 1476-4598, 03/2010, Volume 9, Issue 1, pp. 55 - 55
Background: Wnt-11 is a secreted protein that modulates cell growth, differentiation and morphogenesis during development. We previously reported that Wnt-11...
PATHWAYS | GASTRULATION MOVEMENTS | MORPHOGENESIS | STEM-CELLS | WNT11 | MESODERM | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | RECEPTOR | PROGRESSION | TRANSDIFFERENTIATION | Cell Survival - drug effects | Prostatic Neoplasms - pathology | Gene Silencing - drug effects | Neuroendocrine Cells - pathology | Apoptosis - drug effects | Neoplasm Invasiveness | Humans | Androgens - deficiency | Male | Down-Regulation - drug effects | Wnt Proteins - metabolism | Down-Regulation - genetics | Cell Movement - drug effects | Prostatic Neoplasms - genetics | Wnt Proteins - genetics | Androgens - pharmacology | Cell Differentiation - drug effects | Cell Line, Tumor | Neuroendocrine Cells - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neuroendocrine Cells - drug effects | Care and treatment | Development and progression | Cellular signal transduction | Genetic aspects | Research | Gene expression | Health aspects | Prostate cancer | Risk factors | Medical research | Rodents | Smooth muscle | Standard deviation | Manuscripts | Cell adhesion & migration
PATHWAYS | GASTRULATION MOVEMENTS | MORPHOGENESIS | STEM-CELLS | WNT11 | MESODERM | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | RECEPTOR | PROGRESSION | TRANSDIFFERENTIATION | Cell Survival - drug effects | Prostatic Neoplasms - pathology | Gene Silencing - drug effects | Neuroendocrine Cells - pathology | Apoptosis - drug effects | Neoplasm Invasiveness | Humans | Androgens - deficiency | Male | Down-Regulation - drug effects | Wnt Proteins - metabolism | Down-Regulation - genetics | Cell Movement - drug effects | Prostatic Neoplasms - genetics | Wnt Proteins - genetics | Androgens - pharmacology | Cell Differentiation - drug effects | Cell Line, Tumor | Neuroendocrine Cells - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neuroendocrine Cells - drug effects | Care and treatment | Development and progression | Cellular signal transduction | Genetic aspects | Research | Gene expression | Health aspects | Prostate cancer | Risk factors | Medical research | Rodents | Smooth muscle | Standard deviation | Manuscripts | Cell adhesion & migration
Journal Article
1989, ISBN 0632019778, viii, 160
Book
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