Nature Genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 4, pp. 427 - 437
To connect human biology to fish biomedical models, we sequenced the genome of spotted gar (Lepisosteus oculatus), whose lineage diverged from teleosts before...
MHC CLASS-I | PROVIDES INSIGHTS | COMPLEX-CLASS-I | ANCESTRAL VERTEBRATE | GENE NOMENCLATURE | GENETICS & HEREDITY | TRANSPOSABLE ELEMENTS | RAY-FINNED FISH | BONY FISH | HOX GENES | COMPREHENSIVE ANALYSIS | Fishes - genetics | Fishes - metabolism | Animals | Humans | Transcriptome | Female | Models, Genetic | Genome | Organ Specificity | Sequence Analysis, DNA | Karyotype | Evolution, Molecular | Genetic research | Evolutionary genetics | Genotype | Genetic aspects | Research | Teleostei | Identification and classification | Proteins | Hypotheses | Biomedical research | Councils | Genomics | Zebrafish | Evolution | Biology | Genomes | Grants | Gene expression | Chromosomes | Models animals en la investigació | Animal models in research | Teleostis | Life Sciences | GWAS | comparative medicine | zebrafish | polyploidy | medaka | neofunctionalization | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
MHC CLASS-I | PROVIDES INSIGHTS | COMPLEX-CLASS-I | ANCESTRAL VERTEBRATE | GENE NOMENCLATURE | GENETICS & HEREDITY | TRANSPOSABLE ELEMENTS | RAY-FINNED FISH | BONY FISH | HOX GENES | COMPREHENSIVE ANALYSIS | Fishes - genetics | Fishes - metabolism | Animals | Humans | Transcriptome | Female | Models, Genetic | Genome | Organ Specificity | Sequence Analysis, DNA | Karyotype | Evolution, Molecular | Genetic research | Evolutionary genetics | Genotype | Genetic aspects | Research | Teleostei | Identification and classification | Proteins | Hypotheses | Biomedical research | Councils | Genomics | Zebrafish | Evolution | Biology | Genomes | Grants | Gene expression | Chromosomes | Models animals en la investigació | Animal models in research | Teleostis | Life Sciences | GWAS | comparative medicine | zebrafish | polyploidy | medaka | neofunctionalization | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2016, Volume 113, Issue 34, pp. E5014 - E5023
Antigen processing and presentation genes found within the MHC are among the most highly polymorphic genes of vertebrate genomes, providing populations with...
Comparative genomics | Proteasome and TAP evolution | CG2 clonal zebrafish | MHC class I pathway | Major histocompatibility | COEVOLUTION | GENOMIC ORGANIZATION | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | comparative genomics | REGION | MHC CLASS-I | PRIMITIVE VERTEBRATES | proteasome and TAP evolution | ORIGIN | major histocompatibility | PROTEASOME | SEQUENCE | ANCIENT ALLELIC LINEAGES | Haplotypes | Zebrafish Proteins - classification | Zebrafish - immunology | Transcriptome | Phylogeny | Zebrafish - classification | Antigen Presentation | Protein Isoforms - classification | Zebrafish Proteins - immunology | Proteasome Endopeptidase Complex - immunology | Cloning, Organism | Histocompatibility Antigens Class I - immunology | Histocompatibility Antigens Class I - genetics | Zebrafish - genetics | Biological Evolution | Proteasome Endopeptidase Complex - genetics | Animals | Cysteine Endopeptidases - genetics | Histocompatibility Antigens Class I - classification | High-Throughput Nucleotide Sequencing | Zebrafish Proteins - genetics | Genome | Protein Isoforms - immunology | Cysteine Endopeptidases - classification | Cysteine Endopeptidases - immunology | Protein Isoforms - genetics | Antigens | Genetic aspects | Observations | Health aspects | Zebra fish | Biological Sciences | PNAS Plus
Comparative genomics | Proteasome and TAP evolution | CG2 clonal zebrafish | MHC class I pathway | Major histocompatibility | COEVOLUTION | GENOMIC ORGANIZATION | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | comparative genomics | REGION | MHC CLASS-I | PRIMITIVE VERTEBRATES | proteasome and TAP evolution | ORIGIN | major histocompatibility | PROTEASOME | SEQUENCE | ANCIENT ALLELIC LINEAGES | Haplotypes | Zebrafish Proteins - classification | Zebrafish - immunology | Transcriptome | Phylogeny | Zebrafish - classification | Antigen Presentation | Protein Isoforms - classification | Zebrafish Proteins - immunology | Proteasome Endopeptidase Complex - immunology | Cloning, Organism | Histocompatibility Antigens Class I - immunology | Histocompatibility Antigens Class I - genetics | Zebrafish - genetics | Biological Evolution | Proteasome Endopeptidase Complex - genetics | Animals | Cysteine Endopeptidases - genetics | Histocompatibility Antigens Class I - classification | High-Throughput Nucleotide Sequencing | Zebrafish Proteins - genetics | Genome | Protein Isoforms - immunology | Cysteine Endopeptidases - classification | Cysteine Endopeptidases - immunology | Protein Isoforms - genetics | Antigens | Genetic aspects | Observations | Health aspects | Zebra fish | Biological Sciences | PNAS Plus
Journal Article
3.
Full Text
The confounding complexity of innate immune receptors within and between teleost species
Fish and Shellfish Immunology, ISSN 1050-4648, 06/2016, Volume 53, pp. 24 - 34
Teleost genomes encode multiple multigene families of immunoglobulin domain-containing innate immune receptors (IIIRs) with unknown function and no clear...
Gene content haplotype | Diverse immunoglobulin domain containing proteins | Novel immunoglobulin-like transcripts | Novel immune-type receptors | Polymeric immunoglobulin receptor-like proteins | DISPARATE DISTRIBUTION | CHANNEL CATFISH | RAINBOW-TROUT | ONCORHYNCHUS-MYKISS | ICTALURUS-PUNCTATUS | IG-LIKE DOMAINS | IMMUNOLOGY | IMMUNOGLOBULIN-LIKE TRANSCRIPTS | VARIABLE DOMAINS | GENETIC DIVERSITY | FISHERIES | MULTIGENE FAMILIES | MARINE & FRESHWATER BIOLOGY | VETERINARY SCIENCES | Genetic Variation | Fishes - genetics | Animals | Genome | Immunity, Innate | Receptors, Immunologic - genetics | Fishes - immunology | Tyrosine | Fc receptors | Killer cells | Anopheles | Phosphoproteins | Analysis | Genes | Genomics | Evolution
Gene content haplotype | Diverse immunoglobulin domain containing proteins | Novel immunoglobulin-like transcripts | Novel immune-type receptors | Polymeric immunoglobulin receptor-like proteins | DISPARATE DISTRIBUTION | CHANNEL CATFISH | RAINBOW-TROUT | ONCORHYNCHUS-MYKISS | ICTALURUS-PUNCTATUS | IG-LIKE DOMAINS | IMMUNOLOGY | IMMUNOGLOBULIN-LIKE TRANSCRIPTS | VARIABLE DOMAINS | GENETIC DIVERSITY | FISHERIES | MULTIGENE FAMILIES | MARINE & FRESHWATER BIOLOGY | VETERINARY SCIENCES | Genetic Variation | Fishes - genetics | Animals | Genome | Immunity, Innate | Receptors, Immunologic - genetics | Fishes - immunology | Tyrosine | Fc receptors | Killer cells | Anopheles | Phosphoproteins | Analysis | Genes | Genomics | Evolution
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Developmental and Comparative Immunology, ISSN 0145-305X, 07/2019, Volume 96, pp. 83 - 92
Journal Article
01/2017, ISBN 9780355635775
The zebrafish (Danio rerio) is a useful model for studying gene function and evolution and has recently gained momentum as a model for studying the...
Immunology | Genetics
Immunology | Genetics
Dissertation
Immunogenetics, ISSN 0093-7711, 04/2016, Volume 68, Issue 4, pp. 295 - 312
Bony fish encode multiple multi-gene families of membrane receptors that are comprised of immunoglobulin (Ig) domains and are predicted to function in innate...
Innate immunity | Immune receptor | Haplotype | Immunoglobulin domain | Polymorphism | LIGAND-BINDING | MODEL | IMMUNOLOGY | CYPRINUS-CARPIO | FAMILY | GENOME SEQUENCE | IMMUNE-SYSTEM | NONSENSE-MEDIATED DECAY | GENETICS & HEREDITY | TELEOST FISH | COPY NUMBER VARIATION | CELL-RECEPTOR | Haplotypes | Lipids - genetics | Zebrafish - immunology | Genes, MHC Class I - genetics | Immunoglobulins - genetics | Immunity, Innate | Zebrafish - growth & development | Zebrafish - genetics | Animals | Gene Expression Regulation, Developmental | Genes, MHC Class I - immunology | Zebrafish Proteins - immunology | Receptors, Immunologic - immunology | Zebrafish Proteins - genetics | Receptors, Immunologic - genetics | Genetic Linkage | Embryonic development | Carp | Fishes | Genes | Genomics | Genetic research | Genetic polymorphisms
Innate immunity | Immune receptor | Haplotype | Immunoglobulin domain | Polymorphism | LIGAND-BINDING | MODEL | IMMUNOLOGY | CYPRINUS-CARPIO | FAMILY | GENOME SEQUENCE | IMMUNE-SYSTEM | NONSENSE-MEDIATED DECAY | GENETICS & HEREDITY | TELEOST FISH | COPY NUMBER VARIATION | CELL-RECEPTOR | Haplotypes | Lipids - genetics | Zebrafish - immunology | Genes, MHC Class I - genetics | Immunoglobulins - genetics | Immunity, Innate | Zebrafish - growth & development | Zebrafish - genetics | Animals | Gene Expression Regulation, Developmental | Genes, MHC Class I - immunology | Zebrafish Proteins - immunology | Receptors, Immunologic - immunology | Zebrafish Proteins - genetics | Receptors, Immunologic - genetics | Genetic Linkage | Embryonic development | Carp | Fishes | Genes | Genomics | Genetic research | Genetic polymorphisms
Journal Article
Biological Invasions, ISSN 1387-3547, 5/2012, Volume 14, Issue 5, pp. 929 - 937
Numerous invasive aquatic species introductions can be traced to the aquarium trade. Many potentially harmful aquarium species may be difficult to identify...
Life Sciences | Myriophyllum | Taxonomy | Aquarium trade | Freshwater & Marine Ecology | Water gardening | ITS | Ecology | Developmental Biology | Plant Sciences | Invasion | BIOLOGICAL INVASIONS | E-COMMERCE | PATHWAY | ECOLOGY | CAULERPA | BIODIVERSITY CONSERVATION | Genetic research | Invasive species | Aquatic resources | Plant introductions | Morphology | Aquatic plants | Nonnative species
Life Sciences | Myriophyllum | Taxonomy | Aquarium trade | Freshwater & Marine Ecology | Water gardening | ITS | Ecology | Developmental Biology | Plant Sciences | Invasion | BIOLOGICAL INVASIONS | E-COMMERCE | PATHWAY | ECOLOGY | CAULERPA | BIODIVERSITY CONSERVATION | Genetic research | Invasive species | Aquatic resources | Plant introductions | Morphology | Aquatic plants | Nonnative species
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Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, ISSN 1552-5007, 11/2017, Volume 328, Issue 7, pp. 666 - 684
Journal Article
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, ISSN 1552-5007, 11/2017, Volume 328, Issue 7, pp. 666 - 684
ABSTRACT The resolution of the gar genome affords an opportunity to examine the diversification and functional specialization of immune effector molecules at a...
CHANNEL CATFISH | RAINBOW-TROUT | BONY FISH | FUNCTIONAL-CHARACTERIZATION | ICTALURUS-PUNCTATUS | DEVELOPMENTAL BIOLOGY | IMMUNOGLOBULIN-LIKE TRANSCRIPTS | MHC CLASS-I | GENOME DUPLICATION | EVOLUTIONARY BIOLOGY | ZOOLOGY | TOLL-LIKE RECEPTORS | LIPOPOLYSACCHARIDE LPS | Biological Evolution | Amino Acid Sequence | Fishes - genetics | Animals | Gene Expression Regulation - immunology | Immunity, Innate - physiology | Immunity, Innate - genetics | Fishes - immunology | Toll-like receptors | novel immune-type receptors | diverse immunoglobulin domain-containing proteins | Holostei | teleost | Actinopterygii
CHANNEL CATFISH | RAINBOW-TROUT | BONY FISH | FUNCTIONAL-CHARACTERIZATION | ICTALURUS-PUNCTATUS | DEVELOPMENTAL BIOLOGY | IMMUNOGLOBULIN-LIKE TRANSCRIPTS | MHC CLASS-I | GENOME DUPLICATION | EVOLUTIONARY BIOLOGY | ZOOLOGY | TOLL-LIKE RECEPTORS | LIPOPOLYSACCHARIDE LPS | Biological Evolution | Amino Acid Sequence | Fishes - genetics | Animals | Gene Expression Regulation - immunology | Immunity, Innate - physiology | Immunity, Innate - genetics | Fishes - immunology | Toll-like receptors | novel immune-type receptors | diverse immunoglobulin domain-containing proteins | Holostei | teleost | Actinopterygii
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2016, Volume 113, Issue 34, p. E5014
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 08/2016, Volume 113, Issue 34, pp. E5014 - E5014
Antigen processing and presentation genes found within the MHC are among the most highly polymorphic genes of vertebrate genomes, providing populations with...
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 09/2014, Volume 46, Issue 1, pp. 24 - 34
Five large multigene families encoding innate-type immune receptors that are comprised of immunoglobulin domains have been identified in bony fish, of which...
Diverse immunoglobulin domain containing proteins | Novel immunoglobulin-like transcripts | Leukocyte immune-type receptors | Novel immune-type receptors | Polymeric immunoglobulin receptor-like proteins | IMMUNOREGULATORY RECEPTORS | RAINBOW-TROUT | MUCOSAL IMMUNITY | BONY FISH | IMMUNOLOGY | MOLECULES | ZOOLOGY | GENE-CLUSTER | POLYMERIC IG RECEPTOR | SURFACE-RECEPTORS | PROTEIN-TYROSINE-PHOSPHATASE | ATLANTIC SALMON | Haplotypes | Receptors, Immunologic - chemistry | Animals | Zebrafish - immunology | Zebrafish Proteins - chemistry | Zebrafish Proteins - immunology | Receptors, Immunologic - immunology | Zebrafish Proteins - genetics | Receptors, Immunologic - genetics | Zebrafish - genetics | Immunoglobulins
Diverse immunoglobulin domain containing proteins | Novel immunoglobulin-like transcripts | Leukocyte immune-type receptors | Novel immune-type receptors | Polymeric immunoglobulin receptor-like proteins | IMMUNOREGULATORY RECEPTORS | RAINBOW-TROUT | MUCOSAL IMMUNITY | BONY FISH | IMMUNOLOGY | MOLECULES | ZOOLOGY | GENE-CLUSTER | POLYMERIC IG RECEPTOR | SURFACE-RECEPTORS | PROTEIN-TYROSINE-PHOSPHATASE | ATLANTIC SALMON | Haplotypes | Receptors, Immunologic - chemistry | Animals | Zebrafish - immunology | Zebrafish Proteins - chemistry | Zebrafish Proteins - immunology | Receptors, Immunologic - immunology | Zebrafish Proteins - genetics | Receptors, Immunologic - genetics | Zebrafish - genetics | Immunoglobulins
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, p. 700
Journal Article
Nature genetics, ISSN 1061-4036, 05/2016, Volume 48, Issue 6, pp. 700 - 700
Genet. 48, 427-437 (2016); published online 7 March 2016; corrected after print 25 April 2016 As we intended, other researchers have been able to use the...
Genomes | Life Sciences
Genomes | Life Sciences
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 700 - 700
Journal Article