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by Nelson, Christopher P and Goel, Anuj and Butterworth, Adam S and Kanoni, Stavroula and Webb, Tom R and Marouli, Eirini and Zeng, Lingyao and Ntalla, Ioanna and Lai, Florence Y and Hopewell, Jemma C and Giannakopoulou, Olga and Jiang, Tao and Hamby, Stephen E and Di Angelantonio, Emanuele and Assimes, Themistocles L and Bottinger, Erwin P and Chambers, John C and Clarke, Robert and Palmer, Colin N A and Cubbon, Richard M and Ellinor, Patrick and Ermel, Raili and Evangelou, Evangelos and Franks, Paul W and Grace, Christopher and Gu, Dongfeng and Hingorani, Aroon D and Howson, Joanna M M and Ingelsson, Erik and Kastrati, Adnan and Kessler, Thorsten and Kyriakou, Theodosios and Lehtimäki, Terho and Lu, Xiangfeng and Lu, Yingchang and März, Winfried and McPherson, Ruth and Metspalu, Andres and Pujades-Rodriguez, Mar and Ruusalepp, Arno and Schadt, Eric E and Schmidt, Amand F and Sweeting, Michael J and Zalloua, Pierre A and Alghalayini, Kamal and Keavney, Bernard D and Kooner, Jaspal S and Loos, Ruth J F and Patel, Riyaz S and Rutter, Martin K and Tomaszewski, Maciej and Tzoulaki, Ioanna and Zeggini, Eleftheria and Erdmann, Jeanette and Dedoussis, George and Björkegren, Johan L M and Schunkert, Heribert and Farrall, Martin and Danesh, John and Samani, Nilesh J and Watkins, Hugh and Deloukas, Panos and Uk Biobank CardioMetab and EPIC-CVD Consortium and CardiogramplusC4D and UK Biobank CardioMetabolic Consortium CHD working group and CARDIoGRAMplusC4D and The UK Biobank CardioMetabolic Consortium CHD working group and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1385 - 1391
Genome-wide association studies (GWAS) in coronary artery disease (CAD) had identified 66 loci at 'genome-wide significance' (P < 5 x 10(-8)) at the time of... 
RISK LOCI | PROFILES | METAANALYSIS | DATABASE | RARE | LOW-FREQUENCY | ANNOTATION | GENETICS & HEREDITY | ATHEROSCLEROSIS | GENETIC-VARIANTS | GENOME-WIDE ASSOCIATION | Coronary artery | Cardiovascular disease | Genomes | Angina | Gene expression | Metabolism | Angina pectoris | Coronary artery disease | Loci | Meta-analysis | Morphogenesis | Studies | Consortia | Nitric oxide | Coronary vessels | Atherosclerosis | Heritability | Lipid metabolism | Bioinformatics | Heart diseases | Genetic Association Studies - standards | Health Information Systems - statistics & numerical data | Genetic Predisposition to Disease - genetics | Meta-Analysis as Topic | Reproducibility of Results | Humans | Risk Factors | Genetic Loci - genetics | Genetic Association Studies - methods | Genotype | United Kingdom | Genome-Wide Association Study - statistics & numerical data | Phenotype | Genetic Association Studies - statistics & numerical data | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Genome-Wide Association Study - standards | Health Information Systems - standards | Genetic aspects | Disease susceptibility | Research | Coronary heart disease | Risk factors | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2009, Volume 106, Issue 15, pp. 6146 - 6151
Journal Article
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 06/2019
Genome-wide association studies have identified chromosome 14q32 as a locus for coronary artery disease. The disease associated variants fall in a hitherto... 
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 5/2009, Volume 18, Issue 9, pp. 1556 - 1565
An extensive protein-protein interaction network has been identified between proteins implicated in inherited ataxias. The protein sacsin, which is mutated in... 
HEAT-SHOCK PROTEINS | DNAJ | SPASTIC ATAXIA | RNA | MOLECULAR CHAPERONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | PROTEASOME | GENETICS & HEREDITY | ARSACS | UBL DOMAIN | ONSET | Cerebellum | Motor systems | Ubiquitin | Brain | Neurodegenerative diseases | Toxicity | Neurons | proteasomes | Amino acids | Hsp70 protein | siRNA | Hsp40 protein | Chaperones | Neuroblastoma cells | Nodes | Mitochondria | Ataxin | Purkinje cells | N-Terminus | Ataxia | Complementation | Protein interaction | Age | Protein Structure, Tertiary | Amino Acid Sequence | Molecular Chaperones | Peptides | Rats, Wistar | ataxin-1 | Humans | Molecular Sequence Data | Rats | Male | Nerve Tissue Proteins | polyglutamine | Nuclear Proteins | Protein Transport | SACS protein, human | Sequence Alignment | Animals | Heat-Shock Proteins | Cell Line, Tumor | Protein Binding | HSP70 Heat-Shock Proteins | sacsin protein, rat | Ataxin-1 | Ataxins | Index Medicus | Atxn1 protein, rat | ATXN1 protein, human | Molecular Chaperones - metabolism | Molecular Chaperones - chemistry | Heat-Shock Proteins - genetics | Peptides - metabolism | Neurons - metabolism | Ataxia - genetics | Nuclear Proteins - genetics | Ataxia - metabolism | Heat-Shock Proteins - metabolism | Molecular Chaperones - genetics | HSP70 Heat-Shock Proteins - genetics | Nuclear Proteins - metabolism | Nerve Tissue Proteins - genetics | HSP70 Heat-Shock Proteins - metabolism | Nerve Tissue Proteins - metabolism | Heat-Shock Proteins - chemistry
Journal Article
Journal of Clinical Pathology, ISSN 0017-5749, 05/1963, Volume 16, Issue 3, p. 220
Electron microscopy of hepatic tissue obtained by percutaneous needle biopsy from nine patients with Gilbert's syndrome has revealed in every case gross... 
Journal Article
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2018, Volume 38, Issue 8, pp. 1837 - 1844
OBJECTIVE—Genome-wide association studies have revealed a robust association between genetic variation on chromosome 15q26.1 and coronary artery disease (CAD)... 
coronary artery disease | monocytes | macrophages | furin | polymorphism, single nucleotide | APOPTOSIS | ACTIVATION | WALL | ATHEROSCLEROSIS | polymorphism | LOCI | CLEAVAGE | PROPROTEIN CONVERTASES | ENZYME | single nucleotide | PERIPHERAL VASCULAR DISEASE | GROWTH-FACTOR | HEMATOLOGY
Journal Article