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2015, ISBN 1498229093, xxi, 352 pages
Book
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 383, Issue 9923, pp. 1129 - 1137
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Ophthalmology | Retinopathies | Choroideremia - physiopathology | Gene Transfer Techniques | Genetic Vectors - administration & dosage | Retinal Detachment - therapy | Humans | Middle Aged | Transgenes - genetics | Fluorescence | Male | Adaptor Proteins, Signal Transducing - genetics | Retinal Detachment - physiopathology | Adenoviridae - genetics | Adult | Aged | Choroideremia - therapy | Visual Acuity - physiology | Injections, Intraocular | Adaptor Proteins, Signal Transducing - administration & dosage | Genetic Therapy - methods | Care and treatment | Gene therapy | Patient outcomes | Choroideremia | Methods | Macular degeneration | Aging | Retina | Index Medicus | Abridged Index Medicus
Journal Article
2013, Health, technology and society, ISBN 1137026545, xiii, 229
Social aspects | Regenerative medicine | Regeneration (Biology) | Biotechnology | Ethics | Medical research | Ethical issues: scientific & technological developments | Society & social sciences | Health, Illness and Medical Sociology | Genetic engineering | Health Policy | Medical Sociology | Medicine | Genetic Engineering | Palgrave Social Sciences Collection | Environmental Engineering/Biotechnology | Environment | Social Policy | Biomedicine general
Book
Nucleic acids research, ISSN 0305-1048, 09/2015, Volume 43, Issue 20, pp. 9645 - 9662
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Algorithms | Biosynthetic Pathways - genetics | Secondary Metabolism - genetics | Biological Products - metabolism | Polyketides - chemistry | Genomics - methods | Metabolomics - methods | Metabolome - genetics | Peptide Synthases - genetics | Genome, Microbial | Index Medicus | Computational Biology
Journal Article
The New England journal of medicine, ISSN 0028-4793, 05/2016, Volume 374, Issue 20, pp. 1996 - 1998
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cataract - complications | Genetic Therapy | Choroideremia - complications | Humans | Retina | Choroideremia - therapy | Visual Acuity | Cataracts | Diabetic retinopathy | Medical research | Congenital diseases | Blindness | Traffic accidents & safety | Injection | Gene therapy | Patients | Acuity | Index Medicus | Abridged Index Medicus
Journal Article
Ophthalmic research, ISSN 0030-3747, 05/2020, Volume 63, Issue 3, pp. 234 - 243
Journal Article
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Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia
Nature medicine, ISSN 1078-8956, 10/2018, Volume 24, Issue 10, pp. 1507 - 1512
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Choroideremia - physiopathology | Dependovirus - genetics | Genetic Therapy | Retinal Degeneration - genetics | Humans | Middle Aged | Retina - physiopathology | Male | Retinal Degeneration - surgery | Choroideremia - surgery | Genetic Vectors - therapeutic use | Retinal Degeneration - physiopathology | Visual Acuity - genetics | Adaptor Proteins, Signal Transducing - therapeutic use | Choroideremia - genetics | Vision, Ocular - genetics | Vision, Ocular - physiology | Adaptor Proteins, Signal Transducing - genetics | Adult | Aged | Choroideremia - therapy | Visual acuity | Care and treatment | Gene therapy | Health aspects | Choroideremia | Patient outcomes | Complications | Retina | Protein deficiency | Patients | Acuity | Proteins | Eye | Vision | Surgery | Blindness | Retinal degeneration | Eye (anatomy) | Degeneration | Index Medicus
Journal Article
Analytical chemistry (Washington), ISSN 0003-2700, 12/2013, Volume 85, Issue 23, pp. 11576 - 11584
Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Mice, Inbred C57BL | Rats | Male | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods | Rats, Sprague-Dawley | Brain Chemistry - physiology | Mice, Knockout | Brain - metabolism | Animals | Adrenal Glands - metabolism | Steroids - metabolism | Mice | Chromatography, Liquid - methods | Adrenal Glands - chemistry | Mass Spectrometry - methods | Steroids - analysis | Tandem Mass Spectrometry - methods | Extraction (Chemistry) | Fourier transformations | Ionization | Mass spectrometry | Analysis | Obesity | Desorption | Tissues | Rodents | Cancer | Index Medicus | Brain | Enzymes | Inhibitors | Imaging | Inhibition | Steroids | Glucocorticoids | 11β-HSD1 | Mass Spectrometry Imaging | Intracrinology
Journal Article
Journal of neurology, neurosurgery and psychiatry, ISSN 0022-3050, 02/2018, Volume 89, Issue 2, pp. 127 - 137
acute disseminated encephalomyelitis | myelin oligodendrocyte glycoprotein antibodies | outcomes | therapy | optic neuritis | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Surgery | Science & Technology | Myelin-Oligodendrocyte Glycoprotein - immunology | Brain - diagnostic imaging | Demyelinating Autoimmune Diseases, CNS - diagnostic imaging | Neuromyelitis Optica - therapy | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Child, Preschool | Infant | Male | Neuromyelitis Optica - immunology | Demyelinating Autoimmune Diseases, CNS - immunology | Demyelinating Autoimmune Diseases, CNS - physiopathology | Young Adult | Rituximab - therapeutic use | Immunotherapy | Myelitis, Transverse - physiopathology | Adult | Female | Child | Optic Neuritis - immunology | Myelitis, Transverse - immunology | Myelitis, Transverse - therapy | Demyelinating Autoimmune Diseases, CNS - therapy | Encephalomyelitis, Acute Disseminated - therapy | Optic Neuritis - therapy | Optic Neuritis - diagnostic imaging | Neuromyelitis Optica - physiopathology | Encephalomyelitis, Acute Disseminated - physiopathology | Myelitis, Transverse - diagnostic imaging | Neuromyelitis Optica - diagnostic imaging | Encephalomyelitis, Acute Disseminated - diagnostic imaging | Magnetic Resonance Imaging | Autoantibodies - immunology | Mycophenolic Acid - therapeutic use | Immunoglobulins, Intravenous - therapeutic use | Optic Neuritis - physiopathology | Encephalomyelitis, Acute Disseminated - immunology | Adolescent | Aged | Prednisone - therapeutic use | Cohort Studies | Immunologic Factors - therapeutic use | Care and treatment | Usage | Demyelinating diseases | Health aspects | Myelin proteins | Multiple sclerosis | Immunoglobulins | Disease | Encephalomyelitis | Laboratories | Aquaporins | Glycoproteins | Patients | Neurology | Software | Adults | Index Medicus | 1506 | Neuro-Inflammation
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Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching
Nature chemical biology, ISSN 1552-4450, 12/2016, Volume 12, Issue 12, pp. 1007 - 1014
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Multigene Family - genetics | Peptide Biosynthesis, Nucleic Acid-Independent - genetics | Algorithms | Peptides - metabolism | Peptides - chemistry | Peptides - genetics | Polyketides - chemistry | Polyketides - metabolism | Biosynthesis | Peptides | Natural products | Bioinformatics | Genes | Index Medicus
Journal Article