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Neuro-Oncology, ISSN 1522-8517, 06/2017, Volume 19, Issue suppl_4, pp. iv29 - iv29
Immunotherapy has recently emerged as an important strategy for treating cancer, but has not been tested extensively in pediatric brain tumors. To determine... 
Abstracts
Journal Article
Nature Neuroscience, ISSN 1097-6256, 08/2018, Volume 21, Issue 8, p. 1139
Journal Article
Nature Neuroscience, ISSN 1097-6256, 02/2018, Volume 21, Issue 2, p. 195
Internal N.sup.6-methyladenosine (m.sup.6A) modification is widespread in messenger RNAs (mRNAs) and is catalyzed by heterodimers of methyltransferase-like... 
Cell proliferation | Histones | Stem cell research | MicroRNA | Research | RNA processing
Journal Article
Neuro-Oncology, ISSN 1522-8517, 06/2018, Volume 20, Issue suppl_2, pp. i131 - i131
Abstract Many immunotherapies act by enhancing the ability of T cells to kill tumor cells. But T cell killing depends on recognition of antigens presented by... 
Abstracts
Journal Article
Cancer Cell, ISSN 1535-6108, 2009, Volume 15, Issue 2, pp. 135 - 147
The growth of many cancers depends on self-renewing cells called cancer stem cells or tumor-propagating cells (TPCs). In human brain tumors, cells expressing... 
STEMCELL | CELLCYCLE | PROGENITOR CELLS | EXTERNAL GRANULAR LAYER | ONCOLOGY | NEURONAL PRECURSORS | GENE-EXPRESSION | MYELOID-LEUKEMIA | CENTRAL-NERVOUS-SYSTEM | MONOCLONAL-ANTIBODIES | HUMAN HOMOLOG | CANCER STEM-CELLS | BRAIN-TUMORS | CELL BIOLOGY | Neoplasm Transplantation | Lewis X Antigen - genetics | Humans | Brain Neoplasms - pathology | Brain Neoplasms - physiopathology | Glycoproteins - metabolism | Hedgehog Proteins - metabolism | Molecular Sequence Data | Neurons - cytology | Gene Expression Profiling | Stem Cells - cytology | Lewis X Antigen - metabolism | Stem Cells - metabolism | Biomarkers, Tumor | Recombinant Fusion Proteins - metabolism | Antigens, CD - metabolism | Peptides - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hedgehog Proteins - genetics | Neoplastic Stem Cells - metabolism | Mice, Mutant Strains | Microarray Analysis | Medulloblastoma - pathology | Neoplastic Stem Cells - pathology | Neurons - metabolism | Patched Receptors | Tumor Cells, Cultured | Disease Models, Animal | Basic Helix-Loop-Helix Transcription Factors - genetics | Receptors, Cell Surface - metabolism | Medulloblastoma - physiopathology | Survival Rate | Mice, SCID | AC133 Antigen | Animals | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Mice | Receptors, Cell Surface - genetics | Analysis | Medulloblastoma | Brain tumors | Stem cells | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 06/2018, Volume 21, Issue 8, pp. 1 - 1139
In the version of this article initially published online, there were errors in URLs for www.southernbiotech.com, appearing in Methods sections "m6A dot-blot"... 
Journal Article
Nature Neuroscience, ISSN 1097-6256, 02/2018, Volume 21, Issue 2, pp. 195 - 206
Internal N-6-methyladenosine (m(6)A) modification is widespread in messenger RNAs (mRNAs) and is catalyzed by heterodimers of methyltransferase-like protein 3... 
FTO | METHYLATION | DEVELOPMENTAL REGULATORS | MESSENGER-RNA | GENE | CHROMATIN | PROLIFERATION | NUCLEAR-RNA | DIFFERENTIATION | TRANSLATION | NEUROSCIENCES | Embryo, Mammalian | Cell Self Renewal - physiology | Methyltransferases - metabolism | Methyltransferases - genetics | Gene Expression Regulation, Developmental - genetics | Male | RNA, Messenger - metabolism | Cerebral Cortex - cytology | PAX6 Transcription Factor - genetics | Cell Self Renewal - genetics | Neurogenesis - genetics | Cell Differentiation - genetics | Deoxyadenosines - genetics | Female | Neurogenesis - drug effects | Protein Synthesis Inhibitors - pharmacology | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | PAX6 Transcription Factor - metabolism | Mice, Inbred C57BL | Gene Expression Regulation, Developmental - drug effects | Neural Stem Cells - physiology | Mice, Transgenic | Deoxyadenosines - metabolism | Fibronectins - metabolism | Animals | Cerebral Cortex - embryology | Cell Differentiation - drug effects | Neurogenesis - physiology | Mice | Histones - metabolism | Dactinomycin - pharmacology | RNA modification | Chromatin | Gene regulation | Embryo cells | Cortex | Methyltransferase | Stem cell transplantation | Genomes | Gene expression | Neurogenesis | Mammalian cells | Embryogenesis | Ribonucleic acids | Stem cells | Neural stem cells
Journal Article
by Kool, Marcel and Jones, David T.W and Jäger, Natalie and Northcott, Paul A and Pugh, Trevor J and Hovestadt, Volker and Piro, Rosario M and Esparza, L. Adriana and Markant, Shirley L and Remke, Marc and Milde, Till and Bourdeaut, Franck and Ryzhova, Marina and Sturm, Dominik and Pfaff, Elke and Stark, Sebastian and Hutter, Sonja and Şeker-Cin, Huriye and Johann, Pascal and Bender, Sebastian and Schmidt, Christin and Schmidt, Sabine and Rausch, Tobias and Shih, David and Reimand, Jüri and Sieber, Laura and Wittmann, Andrea and Linke, Linda and Witt, Olaf and Witt, Hendrik and Weber, Ursula D and Zapatka, Marc and König, Rainer and Beroukhim, Rameen and Bergthold, Guillaume and van Sluis, Peter and Volckmann, Richard and Koster, Jan and Versteeg, Rogier and Wolf, Stephan and Lawerenz, Chris and Bartholomae, Cynthia C and von Kalle, Christof and Unterberg, Andreas and Herold-Mende, Christel and Hofer, Silvia and Kulozik, Andreas E and von Deimling, Andreas and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Hasselblatt, Martin and Crawford, John R and Grant, Gerald A and Jabado, Nada and Perry, Arie and Cowdrey, Cynthia and Croul, Sydney and Zadeh, Gelareh and Korbel, Jan O and Doz, Francois and Delattre, Olivier and Bader, Gary D and McCabe, Martin G and Collins, V. Peter and Kieran, Mark W and Cho, Yoon-Jae and Pomeroy, Scott L and Brors, Benedikt and Taylor, Michael D and Schüller, Ulrich and Korshunov, Andrey and Eils, Roland and Wechsler-Reya, Robert J and Lichter, Peter and Pfister, Stefan M and ICGC PedBrain Tumor Project
Cancer Cell, ISSN 1535-6108, 03/2014, Volume 25, Issue 3, pp. 393 - 405
Smoothened (SMO) inhibitors recently entered clinical trials for sonic-hedgehog-driven medulloblastoma (SHH-MB). Clinical response is highly variable. To... 
NERVOUS-SYSTEM | TERT PROMOTER MUTATIONS | ONCOLOGY | GROWTH | HEDGEHOG PATHWAY INHIBITOR | ITRACONAZOLE | PEDIATRIC MEDULLOBLASTOMA | CANCER | TUMORS | MOUSE MODELS | ADULT | CELL BIOLOGY | Neoplasm Transplantation | Oncogene Proteins - genetics | Humans | Zinc Finger Protein Gli2 | Child, Preschool | Molecular Sequence Data | Infant | Male | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Biphenyl Compounds - therapeutic use | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Young Adult | Telomerase - genetics | Hedgehog Proteins - genetics | Base Sequence | Smoothened Receptor | Adult | Female | N-Myc Proto-Oncogene Protein | Patched Receptors | Medulloblastoma - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Child | Pyridines - therapeutic use | Cerebellar Neoplasms - drug therapy | Repressor Proteins - genetics | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Cerebellar Neoplasms - genetics | Mice, SCID | Phosphatidylinositol 3-Kinases - genetics | DEAD-box RNA Helicases - genetics | Drug Resistance, Neoplasm - genetics | Animals | Adolescent | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice, Inbred NOD | High-Throughput Nucleotide Sequencing | Mice | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Kruppel-Like Transcription Factors - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Genetic aspects | Nucleotide sequencing | Analysis | Medulloblastoma | Genomics | DNA sequencing | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 02/2018, Volume 21, Issue 2, pp. 195 - 206
Internal N6-methyladenosine (m6A) modification is widespread in messenger RNAs (mRNAs) and is catalyzed by heterodimers of methyltransferase-like protein 3... 
Index Medicus | H3K27–3me | CBP | neural stem cells | P300 | m6A | H3K27-acetylation | N6-methyladenosine | histone modifications | self-renewal | RNA methylation
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 510, Issue 7506, pp. 537 - 541
Journal Article
by Northcott, Paul A and Shih, David J. H and Peacock, John and Garzia, Livia and Sorana Morrissy, A and Zichner, Thomas and Stútz, Adrian M and Korshunov, Andrey and Reimand, Júri and Schumacher, Steven E and Beroukhim, Rameen and Ellison, David W and Marshall, Christian R and Lionel, Anath C and MacK, Stephen and Dubuc, Adrian and Yao, Yuan and Ramaswamy, Vijay and Luu, Betty and Rolider, Adi and Cavalli, Florence M. G and Wang, Xin and Remke, Marc and Wu, Xiaochong and Chiu, Readman Y. B and Chu, Andy and Chuah, Eric and Corbett, Richard D and Hoad, Gemma R and Jackman, Shaun D and Li, Yisu and Lo, Allan and Mungall, Karen L and Ming Nip, Ka and Qian, Jenny Q and Raymond, Anthony G. J and Thiessen, Nina and Varhol, Richard J and Birol, Inanc and Moore, Richard A and Mungall, Andrew J and Holt, Robert and Kawauchi, Daisuke and Roussel, Martine F and Kool, Marcel and Jones, David T. W and Witt, Hendrick and Fernandez-L, Africa and Kenney, Anna M and Wechsler-Reya, Robert J and Dirks, Peter and Aviv, Tzvi and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Haberler, Christine C and Delattre, Olivier and Reynaud, Stéphanie S and Doz, François F and Pernet-Fattet, Sarah S and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Scheurlen, Wolfram and Eberhart, Charles G and Fèvre-Montange, Michelle and Jouvet, Anne and Pollack, Ian F and Fan, Xing and Muraszko, Karin M and Yancey Gillespie, G and Di Rocco, Concezio and Massimi, Luca and Michiels, Erna M. C and Kloosterhof, Nanne K and French, Pim J and Kros, Johan M and Olson, James M and Ellenbogen, Richard G and Zitterbart, Karel and Kren, Leos and Thompson, Reid C and Cooper, Michael K and Lach, Boleslaw and McLendon, Roger E and Bigner, Darell D and Fontebasso, Adam and Albrecht, Steffen and Jabado, Nada and Lindsey, Janet C and Bailey, Simon and Gupta, Nalin and Weiss, William A and Bognár, László and Klekner, Almos and Van Meter, Timothy E and Kumabe, Toshihiro and Tominaga, Teiji and Elbabaa, Samer K and Leonard, Jeffrey R and Rubin, Joshua B and ...
Nature, ISSN 0028-0836, 08/2012, Volume 487, Issue 7409, pp. 49 - 56
Journal Article