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by Anttila, Verneri and Winsvold, Bendik S and Gormley, Padhraig and Kurth, Tobias and Bettella, Francesco and McMahon, George and Kallela, Mikko and Malik, Rainer and de Vries, Boukje and Terwindt, Gisela and Medland, Sarah E and Todt, Unda and McArdle, Wendy L and Quaye, Lydia and Koiranen, Markku and Ikram, M. Arfan and Lehtimaki, Terho and Stam, Anine H and Ligthart, Lannie and Wedenoja, Juho and Dunham, Ian and Neale, Benjamin M and Palta, Priit and Hamalainen, Eija and Schuerks, Markus and Rose, Lynda M and Buring, Julie E and Ridker, Paul M and Steinberg, Stacy and Stefansson, Hreinn and Jakobsson, Finnbogi and Lawlor, Debbie A and Evans, David M and Ring, Susan M and Farkkila, Markus and Artto, Ville and Kaunisto, Mari A and Freilinger, Tobias and Schoenen, Jean and Frants, Rune R and Pelzer, Nadine and Weller, Claudia M and Zielman, Ronald and Heath, Anew C and Madden, Pamela A. F and Montgomery, Grant W and Martin, Nicholas G and Borck, Guntram and Goebel, Hartmut and Heinze, Axel and Heinze-Kuhn, Katja and Williams, Frances M. K and Hartikainen, Anna-Liisa and Pouta, Anneli and van den Ende, Joyce and Uitterlinden, Ane G and Hofman, Albert and Amin, Najaf and Hottenga, Jouke-Jan and Vink, Jacqueline M and Heikkila, Kauko and Alexander, Michael and Muller-Myhsok, Bertram and Schreiber, Stefan and Meitinger, Thomas and Wichmann, Heinz Erich and Aromaa, Arpo and Eriksson, Johan G and Traynor, Bryan J and Trabzuni, Daniah and Rossin, Elizabeth and Lage, Kasper and Jacobs, Suzanne B. R and Gibbs, J. Raphael and Birney, Ewan and Kaprio, Jaakko and Penninx, Brenda W and Boomsma, Dorret I and van Duijn, Cornelia and Raitakari, Olli and Jarvelin, Marjo-Riitta and Zwart, John-Anker and Cherkas, Lynn and Strachan, David P and Kubisch, Christian and Ferrari, Michel D and van den Maagdenberg, Arn M. J. M and Dichgans, Martin and Wessman, Maija and Smith, George Davey and Stefansson, Kari and Daly, Mark J and Nyholt, Dale R and Chasman, Daniel I and Palotie, Aarno and UK Brain Expression Consortium and Int Headache Genetics Consortium and North Amer Brain Expression and the International Headache Genetics Consortium and North American Brain Expression Consortium
Nature Genetics, ISSN 1061-4036, 08/2013, Volume 45, Issue 8, pp. 912 - U255
Migraine is the most common brain disorder, affecting approximately 14% of the adult population, but its molecular mechanisms are poorly understood. We report... 
PROTEIN | LEWIS(X) | GENES | GENETICS & HEREDITY | DOWN-REGULATION | TRANSFORMING-GROWTH-FACTOR | MUTATIONS | ASSOCIATION | EXPRESSION | FAMILY | Genetic susceptibility | Genetic variation | Migraine | Physiological aspects | Genetic aspects | Research | Risk factors | Studies | Proteins | Signal transduction | Headaches | Population | Genomes | Meta-analysis
Journal Article
by Anttila, Verneri and Bulik-Sullivan, Brendan and Finucane, Hilary K and Walters, Raymond K and Bras, Jose and Duncan, Laramie and Escott-Price, Valentina and Falcone, Guido J and Gormley, Padhraig and Malik, Rainer and Patsopoulos, Nikolaos A and Ripke, Stephan and Wei, Zhi and Yu, Dongmei and Lee, Phil H and Turley, Patrick and Grenier-Boley, Benjamin and Chouraki, Vincent and Kamatani, Yoichiro and Berr, Claudine and Letenneur, Luc and Hannequin, Didier and Amouyel, Philippe and Boland, Anne and Deleuze, Jean-François and Duron, Emmanuelle and Vardarajan, Badri N and Reitz, Christiane and Goate, Alison M and Huentelman, Matthew J and Ilyas Kamboh, M and Larson, Eric B and Rogaeva, Ekaterina and George-Hyslop, Peter St and Hakonarson, Hakon and Kukull, Walter A and Farrer, Lindsay A and Barnes, Lisa L and Beach, Thomas G and Yesim Demirci, F and Head, Elizabeth and Hulette, Christine M and Jicha, Gregory A and Kauwe, John S.K and Kaye, Jeffrey A and Leverenz, James B and Levey, Allan I and Lieberman, Andrew P and Pankratz, Vernon S and Poon, Wayne W and Quinn, Joseph F and Saykin, Andrew J and Schneider, Lon S and Smith, Amanda G and Sonnen, Joshua A and Stern, Robert A and Van Deerlin, Vivianna M and Van Eldik, Linda J and Harold, Denise and Russo, Giancarlo and Rubinsztein, David C and Bayer, Anthony and Tsolaki, Magda and Proitsi, Petra and Fox, Nick C and Hampel, Harald and Owen, Michael J and Mead, Simon and Passmore, Peter and Morgan, Kevin and Nöthen, Markus M and Rossor, Martin and Lupton, Michelle K and Hoffmann, Per and Kornhuber, Johannes and Lawlor, Brian and McQuillin, Andrew and Al-Chalabi, Ammar and Bis, Joshua C and Ruiz, Agustin and Boada, Mercè and Seshadri, Sudha and Beiser, Alexa and Rice, Kenneth and Van Der Lee, Sven J and De Jager, Philip L and Geschwind, Daniel H and Riemenschneider, Matthias and Riedel-Heller, Steffi and Rotter, Jerome I and Ransmayr, Gerhard and Hyman, Bradley T and Cruchaga, Carlos and Alegret, Montserrat and Winsvold, Bendik and Palta, Priit and Farh, Kai-How and Cuenca-Leon, Ester and Furlotte, Nicholas and Kurth, Tobias and ... and Brainstorm Consortium and The Brainstorm Consortium
Science, ISSN 0036-8075, 06/2018, Volume 360, Issue 6395, pp. 1313 - 1313
Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We... 
ANOREXIA-NERVOSA | POPULATION-BASED TWIN | DEFICIT HYPERACTIVITY DISORDER | LONG-TERM SURVIVAL | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | GENETIC CORRELATIONS | BODY-MASS INDEX | MAJOR DEPRESSIVE DISORDER | BIPOLAR DISORDER | GENOME-WIDE ASSOCIATION | Genetic Variation | Mental Disorders - genetics | Genome-Wide Association Study | Phenotype | Brain Diseases - classification | Quantitative Trait, Heritable | Brain Diseases - diagnosis | Humans | Mental Disorders - classification | Risk Factors | Brain Diseases - genetics | Mental Disorders - diagnosis | Anorexia | Disorders | Cognitive ability | Bipolar disorder | Posttraumatic stress disorder | Mental depression | Epidemiology | Risk factors | Consortia | Proteins | Ischemia | Etiology | Classification | Gilles de la Tourette syndrome | Alzheimer's disease | Neurological disorders | Neurodegenerative diseases | Comorbidity | Behavior disorders | Anorexia nervosa | Risk analysis | Patients | Neurological diseases | Correlation analysis | Heritability | Attention deficit disorder | Headache | Mental disorders | Medical services | Schizophrenia | Risk sharing | Genomes | Heterogeneity | Biological effects | Risk assessment | Stroke | Phenotypes | Migraine | Attention deficit hyperactivity disorder | Eating disorders | Personality | Genetic diversity | Statistics | Activity patterns | Crohn's Disease | Population (statistical) | Scaffolding | Diagnostic systems | Alzheimers disease | Life Sciences | Human health and pathology | Mental Disorders | Neurons and Cognition | Brain Diseases | Genetics
Journal Article
by Okbay, Aysu and Baselmans, B.M.L and Neve, Jan-Emmanuel and Turley, Patrick and Nivard, Michel and Fontana, M.A and Meddens, S.F.W and Linnér, R.K and Rietveld, C.A and Derringer, J and Gratten, Jacob and Lee, James J and Liu, J.Z and Vlaming, Ronald and SAhluwalia, T and Buchwald, J and Cavadino, Alana and Frazier-Wood, Alexis C and Furlotte, N.A and Garfield, V and Geisel, M.H and Gonzalez, Juan R and Haitjema, S and Karlsson, Robert and Der Laan, S.W and Ladwig, Karl-Heinz and Lahti, Jari and Lee, Sven and Lind, Penelope and Liu, T and Matteson, L and Mihailov, Evelin and Miller, Mike and CMinica, C and MNolte, I and Mook-Kanamori, Dennis and Most, Peter and Oldmeadow, Christopher and Qian, Yong and Raitakari, Olli and Rawal, R and Realo, A and Rueedi, R and Schmidt, B and Smith, Albert Vernon and Stergiakouli, Evangelia and Tanaka, Toshiko and Taylor, Kent and Wedenoja, J and Wellmann, J and Westra, Harm-Jan and MWillems, S and Zhao, W and Study, LifeLines Cohort and Amin, Najaf and Bakshi, A and Boyle, Patricia and Cherney, S and Cox, S.R and Davies, Gail and Davis, Oliver S and Ding, Jun and Direk, Nese and Eibich, P and Emeny, Rebecca and Fatemifar, G and Faul, J.D and Ferrucci, Luigi and Forstner, Aneas and Gieger, Christian and Gupta, R and Harris, Tamara B and Harris, Juliette and Holliday, Elizabeth and Hottenga, Jouke Jan and Jager, Philip and Kaakinen, Marika and Kajantie, Eero and Karhunen, V and Kolcic, Ivana and Kumari, Meena and Launer, Lenore and Franke, Lude and Li-Gao, R and Koini, M and Loukola, Anu and Marques-Vidal, P and Montgomery, Grant and Mosing, Miriam and Paternoster, Lavinia and Pattie, Alison and Petrovic, Katja and Pulkki-R'back, L and Quaye, Lydia and R'ikkönen, K and Rudan, Igor and Scott, Rodney and Smith, Jennifer A and Sutin, A.R and Trzaskowski, M and ... and LifeLines Cohort Study
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 624 - 633
Journal Article
by Verhoeven, Virginie J. M and Hysi, Pirro G and Wojciechowski, Robert and Fan, Qiao and Guggenheim, Jeremy A and Höhn, René and Macgregor, Stuart and Hewitt, Alex W and Nag, Abhishek and Cheng, Ching-Yu and Yonova-Doing, Ekaterina and Zhou, Xin and Ikram, M. Kamran and Buitendijk, Gabriëlle H. S and McMahon, George and Kemp, John P and Pourcain, Beate St and Simpson, Claire L and Mäkelä, Kari-Matti and Lehtimäki, Terho and Kähönen, Mika and Paterson, Anew D and Hosseini, S. Mohsen and Wong, Hoi Suen and Xu, Liang and Jonas, Jost B and Pärssinen, Olavi and Wedenoja, Juho and Yip, Shea Ping and Ho, Daniel W. H and Pang, Chi Pui and Chen, Li Jia and Burdon, Kathryn P and Craig, Jamie E and Klein, Barbara E. K and Klein, Ronald and Haller, Toomas and Metspalu, Anes and Khor, Chiea-Chuen and Tai, E.-Shyong and Aung, Tin and Vithana, Eranga and Tay, Wan-Ting and Barathi, Veluchamy A and Chen, Peng and Li, Ruoying and Liao, Jiemin and Zheng, Yingfeng and Ong, Rick T and Döring, Angela and Evans, David M and Timpson, Nicholas J and Verkerk, Annemieke J. M. H and Meitinger, Thomas and Raitakari, Olli and Hawthorne, Felicia and Spector, Tim D and Karssen, Lennart C and Pirastu, Mario and Murgia, Federico and Ang, Wei and Mishra, Aniket and Montgomery, Grant W and Pennell, Craig E and Cumberland, Phillippa M and Cotlarciuc, Ioana and Mitchell, Paul and Wang, Jie Jin and Schache, Maria and Janmahasathian, Sarayut and Igo, Robert P and Lass, Jonathan H and Chew, Emily and Iyengar, Sudha K and Gorgels, Theo G. M. F and Rudan, Igor and Hayward, Caroline and Wright, Alan F and Polasek, Ozren and Vatavuk, Zoran and Wilson, James F and Fleck, Brian and Zeller, Tanja and Mirshahi, Alireza and Müller, Christian and Uitterlinden, Ané G and Rivadeneira, Fernando and Vingerling, Johannes R and Hofman, Albert and Oostra, Ben A and Amin, Najaf and Bergen, Arthur A. B and teo, Yik-Ying and Rahi, Jugnoo S and Vitart, Veronique and Williams, Cathy and Baird, Paul N and Wong, Tien-Yin and Oexle, Konrad and Pfeiffer, Norbert and ... and Fuchs' Genetics Multi-Ctr Study Gr and Diabet Control Complications Trial and WTCCC2 and CREAM and Consortium for Refractive Error and Myopia (CREAM) and Fuchs' Genetics Multi-Center Study Group and Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group and Wellcome Trust Case Control Consortium 2 (WTCCC2) and The Fuchs' Genetics Multi-Center Study Group and The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 3, pp. 314 - 318
Journal Article
by Gormley, A.M and Stefansson, Hreinn and Winsvold, Bendik and Palta, Priit and Esko, Tõnu and Pers, Tune and Farh, Kai-How and Cuenca-Leon, E and Muona, M and Furlotte, N.A and Kurth, Karl and Ingason, Anes and Mcmahon, George and Ligthart, Lannie and Terwindt, Gisela and Todt, Unda and Müller-Myhsok, Bertram and Ran, C and Gordon, S.G and Stam, Anine and Steinberg, Stacy and Göbel, Hartmut and Koiranen, Markku and Quaye, Lydia and Adams, H.H.H and Lehtimäki, Terho and Sarin, A.-P and Wedenoja, J and Hinds, David A and Buring, J.E and Schürks, Markus and Ridker, Paul and Hrafnsdottir, M.G and Ring, Susan and Hottenga, Jouke Jan and Penninx, Brenda and Färkkilä, Markus and Artto, Ville and Hämäläinen, Eija and Lucae, Susanne and Malik, Rainer and Heath, Anew C and Madden, Pamela and Martin, Nicholas and Montgomery, Grant and Kurki, M.I and Kals, Mart and Mägi, Reedik and Pärn, K and Hamalainen, Eija and Huang, H and Byrnes, A.E and Franke, Lude and Huang, Jian and Stergiakouli, Evangelia and Lee, Phil and Sandor, C and Webber, C and Cader, Z and Müller-Myhsok, B and Schreiber, Stefan and Meitinger, Thomas and Hagen, Knut and Salomaa, Veikko and Heikkilä, Kauko and Loehrer, Elizabeth and Uitterlinden, Ané and Hofman, A and Duijn, Cornelia and Cherkas, Lynn and Pedersen, L.M and Stubhaug, A and Nielsen, C.S and Männikkö, M and Mihailov, Evelin and Milani, Lili and Esserlind, A.-L and Christensen, A.F and Hansen, T.F and Werge, Thomas and Kaprio, Jaakko and Aromaa, Arpo and Raitakari, Olli and Ikram, Arfan and Ikram, Kamran and Jarvelin, Marjo-Riitta and Metspalu, Anes and Kubisch, Christian and Strachan, David and Ferrari, Michel and Belin, A.C and Wessman, Maija and Maagdenberg, Arn and Zwart, John-Anker and Boomsma, Dorret and Smith, G.D and Stefansson, K and Eriksson, Nicholas and Daly, Mark and Neale, Benjamin and ... and Int Headache Genetics Consortium and International Headache Genetics Consortium
Nature Genetics, ISSN 1061-4036, 08/2016, Volume 48, Issue 8, pp. 856 - 866
Journal Article
by Gunter Schumann and Chunyu Liu and Paul O’Reilly and He Gao and Parkyong Song and Bing Xu and Barbara Ruggeri and Najaf Amin and Tianye Jia and Sarah Preis and Marcelo Segura Lepe and Shizuo Akira and Caterina Barbieri and Sebastian Baumeister and Stephane Cauchi and Toni-Kim Clarke and Stefan Enroth and Kristar Fische and Jenni Hällfors and Sarah E. Harris and Saskia Hieber and Edith Hofer and Jouke-Jan Hottenga and Åsa Johansson and Peter K. Joshi and Niina Kaartinen and Jaana Laitinen and Rozenn Lemaitre and Anu Loukola and Jian’an Luan and Leo-Pekka Lyytikäinen and Massimo Mangino and Ani Manichaikul and Hamdi Mbarek and Yuri Milaneschi and Alireza Moayyeri and Kenneth Mukamal and Christopher Nelson and Jennifer Nettleton and Eemil Partinen and Rajesh Rawal and Antonietta Robino and Lynda Rose and Cinzia Sala and Takashi Satoh and Reinhold Schmidt and Katharina Schraut and Robert Scott and Albert Vernon Smith and John M. Starr and Alexander Teumer and Stella Trompet and André G. Uitterlinden and Cristina Venturini and Anne-Claire Vergnaud and Niek Verweij and Veronique Vitart and Dragana Vuckovic and Juho Wedenoja and Loic Yengo and Bing Yu and Weihua Zhang and Jing Hua Zhao and Dorret I. Boomsma and John Chambers and Daniel I. Chasman and Toniolo Daniela and Eco de Geus and Ian Deary and Johan G. Eriksson and Tõnu Esko and Volker Eulenburg and Oscar H. Franco and Philippe Froguel and Christian Gieger and Hans J. Grabe and Vilmundur Gudnason and Ulf Gyllensten and Tamara B. Harris and Anna-Liisa Hartikainen and Andrew C. Heath and Lynne Hocking and Albert Hofman and Cornelia Huth and Marjo-Riitta Jarvelin and J. Wouter Jukema and Jaakko Kaprio and Jaspal S. Kooner and Zoltan Kutalik and Jari Lahti and Claudia Langenberg and Terho Lehtimäki and Yongmei Liu and Pamela A. F. Madden and Nicholas Martin and Alanna Morrison and Brenda Penninx and Nicola Pirastu and Bruce Psaty and Olli Raitakari and ... and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinsk genetik och genomik and Farmaceutiska fakulteten and Institutionen för farmaceutisk biovetenskap and Uppsala universitet
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2016, Volume 113, Issue 50, pp. 14372 - 14377
Excessive alcohol consumption is a major public health problem worldwide. Although drinking habits are known to be inherited, few genes have been identified... 
Alcohol consumption | Human | β-Klotho | Mouse model | FGF21 | ACTIVATION | mouse model | MULTIDISCIPLINARY SCIENCES | SWEET | alcohol consumption | DEPENDENCE | HEART | DISEASE | LIVER | MICE | human | beta-Klotho | CONSUMPTION | GENOME-WIDE ASSOCIATION | Biological Sciences | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
by Barban, Nicola and Jansen, Rick and de Vlaming, Ronald and Vaez, Ahmad and Mandemakers, Jornt J and Tropf, Felix C and Shen, Xia and Wilson, James F and Chasman, Daniel I and Nolte, Ilja M and Tragante, Vinicius and van der Laan, Sander W and Perry, John R B and Kong, Augustine and Ahluwalia, Tarunveer S and Albrecht, Eva and Yerges-Armstrong, Laura and Atzmon, Gil and Auro, Kirsi and Ayers, Kristin and Bakshi, Anew and Ben-Avraham, Danny and Berger, Klaus and Bergman, Aviv and Bertram, Lars and Bielak, Lawrence F and Bjornsdottir, Gyda and Bonder, Marc Jan and Broer, Linda and Bui, Minh and Barbieri, Caterina and Cavadino, Alana and Chavarro, Jorge E and Turman, Constance and Concas, Maria Pina and Cordell, Heather J and Davies, Gail and Eibich, Peter and Eriksson, Nicholas and Esko, Tõnu and Eriksson, Joel and Falahi, Fahimeh and Felix, Janine F and Fontana, Mark Alan and Franke, Lude and Gandin, Ilaria and Gaskins, Auey J and Gieger, Christian and Gunderson, Erica P and Guo, Xiuqing and Hayward, Caroline and He, Chunyan and Hofer, Edith and Huang, Hongyan and Joshi, Peter K and Kanoni, Stavroula and Karlsson, Robert and Kiechl, Stefan and Kifley, Annette and Kluttig, Alexander and Kraft, Peter and Lagou, Vasiliki and Lecoeur, Cecile and Lahti, Jari and Li-Gao, Ruifang and Lind, Penelope A and Liu, Tian and Makalic, Enes and Mamasoula, Crysovalanto and Matteson, Lindsay and Mbarek, Hamdi and McArdle, Patrick F and McMahon, George and Meddens, S Fleur W and Mihailov, Evelin and Miller, Mike and Missmer, Stacey A and Monnereau, Claire and van der Most, Peter J and Myhre, Ronny and Nalls, Mike A and Nutile, Teresa and Kalafati, Ioanna Panagiota and Porcu, Eleonora and Prokopenko, Inga and Rajan, Kumar B and Rich-Edwards, Janet and Rietveld, Cornelius A and Robino, Antonietta and Rose, Lynda M and Rueedi, Rico and Ryan, Kathleen A and Saba, Yasaman and Schmidt, Daniel and Smith, Jennifer A and Stolk, Lisette and Streeten, Elizabeth and Tönjes, Anke and Thorleifsson, Gudmar and Ulivi, Sheila and ... and Bios Consortium and LifeLines Cohort Study and BIOS Consortium and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature Genetics, ISSN 1061-4036, 12/2016, Volume 48, Issue 12, pp. 1462 - 1472
Journal Article