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PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, p. e0170551
Cudraflavone C (Cud C) is a naturally-occurring flavonol with reported anti-proliferative activities. However, the mechanisms by which Cud C induced... 
LUNG-CANCER | PI3K/AKT PATHWAY | HUMAN BREAST | CUDRANIA-TRICUSPIDATA | MULTIDISCIPLINARY SCIENCES | CYCLIN B1 | CONNECTIVITY MAP | GENE-EXPRESSION | ISOPRENYLATED FLAVONES | ROOT BARK | CLINICAL-SIGNIFICANCE | Caco-2 Cells | Apoptosis - drug effects | HCT116 Cells | Humans | Gene Expression Profiling | HT29 Cells | Signal Transduction - drug effects | Colorectal Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - drug effects | Cell Line, Tumor | Real-Time Polymerase Chain Reaction | Flavones - pharmacology | Proto-Oncogene Proteins c-akt - drug effects | Phosphoinositides | Colorectal cancer | Genetic aspects | Research | Gene expression | Health aspects | Apoptosis | Cell proliferation | Phosphorylation | Toxicity | Epithelial cells | Colorectal carcinoma | Clinical trials | Cytotoxicity | AKT protein | Oncology | Insulin-like growth factors | Metastasis | Kinases | Phosphatase | Cancer therapies | Depolarization | Signal transduction | Mitochondria | Cell activation | Cell growth | Inhibition | Huwe1 protein | Medical research | EGR-1 protein | Caspase | Protein biosynthesis | Pharmacology | Breast cancer | FDA approval | Chemical compounds | 1-Phosphatidylinositol 3-kinase | Studies | Signaling | DNA microarrays | Inhibitors | Protein synthesis | Pharmacy | Stem cells | Lipid kinase | Tumor suppressor genes | Mutation | Cancer
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4909 - 4917
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, p. 42504
Precursor mRNA (pre-mRNA) splicing is catalyzed by a large ribonucleoprotein complex known as the spliceosome. Numerous studies have indicated that aberrant... 
TARGET | UVEAL MELANOMA | MULTIDISCIPLINARY SCIENCES | SPLICEOSOME | MACHINERY | BIOLOGICAL EVALUATION | MESSENGER-RNA DECAY | MUTATIONS | CANCER | ASSOCIATION | MYELODYSPLASTIC SYNDROMES | Indole | Polymerization | mRNA | Genomes | Breast cancer | Tumor cell lines | Proteins | Tubulin | Antitumor agents | Cell death | Cell cycle | Antitumor activity | Splicing factors | Apoptosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 12, pp. 3317 - 3322
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2018, Volume 28, Issue 3, p. 302
A series of thirty-four diarylpentanoids derivatives were synthesized and evaluated for their [alpha]-glucosidase inhibitory activity. Eleven compounds (19,... 
Analysis | Resveratrol
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2018, Volume 28, Issue 3, pp. 302 - 309
[Display omitted] A series of thirty-four diarylpentanoids derivatives were synthesized and evaluated for their α-glucosidase inhibitory activity. Eleven... 
Polyhydroxyphenyl | Docking | Diarylpentanoids | Furanyl | α-Glucosidase inhibitory activity | CHEMISTRY, MEDICINAL | ANTICANCER AGENTS | CHEMISTRY, ORGANIC | DIABETES-MELLITUS | ANTIINFLAMMATORY AGENTS | ANTIOXIDANT | BIOLOGICAL EVALUATION | alpha-Glucosidase inhibitory activity | CURCUMIN ANALOGS | MONOCARBONYL ANALOGS
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2018, Volume 157, pp. 716 - 728
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 11/2019, Volume 28, Issue 11, pp. 2002 - 2009
A series of seven new (1, 3, 6, 7, 10, 12, and 13) and six (2, 4, 5, 8, 9, and 11) known diarylpentanoid analogs were synthesized and assessed for their nitric... 
Biochemistry, general | α-glucosidase | Biomedicine | Antiinflammatory | Docking | Diarylpentanoids | Pharmacology/Toxicology | Antioxidant | Cell Biology | Antioxidants | Synthesis | Scavenging | Nitric oxide | Glucosidase | Curcumin | Hydrophobicity | Molecular docking
Journal Article
Journal Article