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Neurobiology of Aging, ISSN 0197-4580, 09/2019, Volume 81, pp. 138 - 145
The regional relationships between tau positron emission tomography (PET) imaging and cognitive impairment in Alzheimer's disease (AD) remain uncertain. We... 
Tau | Clinical trial | Cognition | Alzheimer's disease | PET | Development and progression | PET imaging | Tracers (Biology) | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e31814 - e31814
Microglia are specialized immune cells of the brain. Upon insult, microglia initiate a cascade of cellular responses including a characteristic change in cell... 
PROTEIN | NEUROINFLAMMATION | INFLAMMATION | BIOLOGY | DYNAMICS | INJURY | CNS | EXPRESSION | BRAIN | Calcium-Binding Proteins - metabolism | Microglia - cytology | Green Fluorescent Proteins - metabolism | Microglia - metabolism | Reproducibility of Results | Central Nervous System - metabolism | Microglia - drug effects | Mice, Inbred C57BL | Mice, Transgenic | Green Fluorescent Proteins - genetics | Microscopy, Confocal - methods | Receptors, HIV - genetics | Antigens, CD - metabolism | Immunohistochemistry - methods | Animals | Receptors, HIV - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Lipopolysaccharides - pharmacology | Mice | Microfilament Proteins - metabolism | Receptors, Cytokine - metabolism | CX3C Chemokine Receptor 1 | Receptors, Cytokine - genetics | Immunohistochemistry | Fluorescence | Technology application | Mitogens | Methods | Brain | Shape | Traumatic brain injury | Segmentation | Image processing | Cytology | Central nervous system | Cell morphology | Rodents | Iterative methods | Activation analysis | Immune system | Antigens | Automation | Immune response | Dendritic cells | Cortex | Data processing | Gene expression | Microglia | Immune systems | Image segmentation | Dynamic tests | Image analysis | Microscopy | Roundness | Morphology | Cell size | Brain injury | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 12/2013, Volume 80, Issue 5, pp. 1175 - 1189
Axon degeneration is widespread both in neurodegenerative disease and in normal neural development, but the molecular pathways regulating these degenerative... 
PERIPHERAL-NERVE | APOPTOSIS | ACTIVATION | UBIQUITIN-PROTEASOME SYSTEM | PATHWAY | WALLERIAN DEGENERATION | DISEASE | DEATH | CLEAVAGE | FRAGMENTATION | NEUROSCIENCES | Neurons - pathology | Calpain - metabolism | Wallerian Degeneration - pathology | Cytoskeletal Proteins - genetics | Embryo, Mammalian | Nicotinamide-Nucleotide Adenylyltransferase - metabolism | Humans | Cell Survival - genetics | Ganglia, Spinal - cytology | Green Fluorescent Proteins - genetics | Armadillo Domain Proteins - genetics | RNA, Messenger - metabolism | Sciatic Neuropathy - complications | Nerve Degeneration - metabolism | Axotomy | Neurons - ultrastructure | Time Factors | HEK293 Cells | Cytoskeletal Proteins - metabolism | Disease Models, Animal | Animals, Newborn | Calcium-Binding Proteins - metabolism | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | Brain - cytology | Nerve Growth Factor - metabolism | Transduction, Genetic | Wallerian Degeneration - physiopathology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Gene Expression Regulation - physiology | Ganglia, Spinal - ultrastructure | Nerve Tissue Proteins - metabolism | Animals | Armadillo Domain Proteins - metabolism | Nicotinamide-Nucleotide Adenylyltransferase - genetics | Mice | In Vitro Techniques | Nerve Degeneration - etiology | Sciatic Neuropathy - metabolism | Calcium-Binding Proteins - genetics | RNA, Small Interfering - metabolism | Physiological aspects | Calpain | Nervous system diseases | Analysis | Medical research | Microscopy | Mammals | Neurodegeneration | Lasers | Index Medicus
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e68755 - e68755
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2012, Volume 32, Issue 49, pp. 17540 - 17553
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2012, Volume 32, Issue 28, pp. 9677 - 9689
Passive immunization against beta-amyloid (A beta) has become an increasingly desirable strategy as a therapeutic treatment for Alzheimer's disease (AD).... 
APP TRANSGENIC MICE | NATURAL OLIGOMERS | HUMAN IGG1 | ALZHEIMERS-DISEASE | PROTEIN-KINASE | LONG-TERM POTENTIATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | PASSIVE-IMMUNIZATION | SECRETED OLIGOMERS | P38 MAP KINASE | Microglia - metabolism | Humans | Middle Aged | Male | Green Fluorescent Proteins - genetics | Neuroprotective Agents - metabolism | Alzheimer Disease - pathology | Neuroprotective Agents - pharmacology | Time Factors | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Statistics, Nonparametric | Aged, 80 and over | Neurons - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Alzheimer Disease - immunology | Receptors, Chemokine - genetics | Plaque, Amyloid - immunology | Disease Models, Animal | Animals, Newborn | Rats | Mice, Transgenic | Mutation - genetics | Rats, Sprague-Dawley | Microscopy, Confocal | Plaque, Amyloid - metabolism | Mice | CX3C Chemokine Receptor 1 | Alzheimer Disease - blood | Immunoglobulin G - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dose-Response Relationship, Immunologic | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Immunoglobulin G - pharmacology | Female | Neurons - drug effects | Peptide Fragments - metabolism | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Plaque, Amyloid - pathology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Alzheimer Disease - therapy | Cells, Cultured | Presenilin-1 - genetics | Hippocampus - cytology | Gene Expression Regulation - drug effects | Amyloid beta-Protein Precursor - genetics | Animals | Amyloid beta-Peptides - immunology | Aged | Index Medicus
Journal Article