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Journal of Clinical Investigation, ISSN 0021-9738, 12/2007, Volume 117, Issue 12, pp. 3664 - 3672
Mammalian TLRs are central mediators of the innate immune system that instruct cells of the innate and adaptive response to clear microbial infections. Here,... 
NEUTROPHIL NADPH OXIDASE | MEDICINE, RESEARCH & EXPERIMENTAL | CANDIDA-ALBICANS | RECOGNITION | IMMUNE-RESPONSES | ORAL CANDIDOSIS | ENDOTHELIAL-CELLS | TOLL-LIKE RECEPTORS | HOST-DEFENSE | MODEL | EXPRESSION | Tumor Necrosis Factor-alpha - metabolism | Epithelial Cells - metabolism | Toll-Like Receptor 4 - biosynthesis | Coculture Techniques | Humans | Immunity, Mucosal - drug effects | Signal Transduction - immunology | RNA, Small Interfering - immunology | Immunity, Innate - physiology | Tumor Necrosis Factor-alpha - immunology | Antibodies - immunology | Immunity, Mucosal - physiology | Neutrophils - microbiology | Toll-Like Receptor 4 - antagonists & inhibitors | Candidiasis - immunology | Candidiasis - pathology | Mouth Mucosa - pathology | Neutrophils - metabolism | Neutrophils - pathology | Mouth Mucosa - microbiology | Immunity, Innate - drug effects | RNA, Small Interfering - pharmacology | Cells, Cultured | Mouth Mucosa - immunology | Neutrophils - immunology | Epithelial Cells - pathology | Toll-Like Receptor 4 - immunology | Candida albicans - immunology | Antibodies - pharmacology | Up-Regulation - drug effects | Candidiasis - metabolism | Mouth Mucosa - metabolism | Signal Transduction - drug effects | Up-Regulation - immunology | Models, Biological | Epithelial Cells - immunology | Epithelial Cells - microbiology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Mycoses | Control | Properties | Epithelial cells | Health aspects
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2015, Volume 112, Issue 7, pp. 2163 - 2168
Interleukin 4 (IL-4) can suppress delayed-type hypersensitivity reactions (DTHRs), including organ-specific autoimmune diseases in mice and humans. Despite the... 
IL-4 | Biological Sciences | dendritic cells | IL-23 | TH17 | psoriasis
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 03/2019, Volume 40, Issue 3, pp. 187 - 197
Lipopolysaccharide (LPS) sensing in the cytosol by the noncanonical inflammasome leads to pyroptosis and NLRP3 inflammasome activation. This mechanism may be... 
pyroptosis | outer membrane vesicles | caspases | IL-1beta | LPS | sepsis | Health aspects | Mitogens | Protein binding | Index Medicus
Journal Article
Nature Protocols, ISSN 1754-2189, 01/2007, Volume 1, Issue 6, pp. 2767 - 2773
Journal Article
The Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 07/2017, Volume 171, p. 201
Glucocorticoids (GCs) induce Toll-like receptor (TLR) 2 expression and synergistically upregulate TLR2 with pro-inflammatory cytokines or bacteria. These... 
TRAF6 protein | Cytokines | Glucocorticoids | Calcium | Keratinocytes | MAP kinase | JNK protein | T cell receptors | Gene expression | Studies | TLR1 protein | Molecular modelling | TLR2 protein | Toll-like receptors | MyD88 protein | Fibroblasts | Skin diseases
Journal Article
Immunology, ISSN 0019-2805, 02/2015, Volume 144, Issue 2, pp. 218 - 230
Summary The specific function of human skin‐resident dendritic cell (DC) subsets in the regulation of immunity or tolerance is still a matter of debate.... 
interleukin‐1β | Langerhans cells | dendritic cells | Toll‐like receptors | tumour necrosis factor‐α | Toll-like receptors | Tumour necrosis factor-α | Dendritic cells | Interleukin-1β | MIGRATION | IMMUNE-RESPONSE | ACTIVATION | interleukin-1 | LYMPH-NODES | RECEPTOR EXPRESSION | IMMUNOLOGY | CUTTING EDGE | SEMI-MATURE | tumour necrosis factor | STEADY-STATE | SKIN | DIFFERENTIATION | Receptors, CCR7 - immunology | Up-Regulation | Interleukin-1beta - pharmacology | Antigens, CD - biosynthesis | Humans | Membrane Glycoproteins - biosynthesis | Th1 Cells - immunology | Lipopolysaccharides | RNA, Messenger - biosynthesis | Lymphocyte Activation - immunology | Bacterial Infections - immunology | Langerhans Cells - immunology | Immunoglobulins - biosynthesis | Interleukin-12 - biosynthesis | Poly I-C - pharmacology | Toll-Like Receptors - immunology | Cells, Cultured | Inflammation - immunology | Tumor Necrosis Factor-alpha - pharmacology | B7-2 Antigen - biosynthesis | Interferon Type I - genetics | Interleukin-23 - biosynthesis | Interleukin-6 - biosynthesis | Th17 Cells - immunology | Cell Movement | Interferon Inducers - pharmacology | Antiviral agents | Skin | Biological response modifiers | T cells | Cytokines | Rodents | Immune system | Index Medicus | tumour necrosis factor-α | Original | interleukin-1β
Journal Article