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by Huyghe, Jeroen R and Bien, Stephanie A and Harrison, Tabitha A and Kang, Hyun Min and Chen, Sai and Schmit, Stephanie L and Conti, David V and Qu, Conghui and Jeon, Jihyoun and Edlund, Christopher K and Greenside, Peyton and Wainberg, Michael and Schumacher, Fredrick R and Smith, Joshua D and Levine, David M and Nelson, Sarah C and Sinnott-Armstrong, Nasa A and Albanes, Demetrius and Alonso, M. Henar and Anderson, Kristin and Arnau-Collell, Coral and Arndt, Volker and Bamia, Christina and Banbury, Barbara L and Baron, John A and Berndt, Sonja I and Bézieau, Stéphane and Bishop, D. Timothy and Boehm, Juergen and Boeing, Heiner and Brenner, Hermann and Brezina, Stefanie and Buch, Stephan and Buchanan, Daniel D and Burnett-Hartman, Andrea and Butterbach, Katja and Caan, Bette J and Campbell, Peter T and Carlson, Christopher S and Castellví-Bel, Sergi and Chan, Andrew T and Chang-Claude, Jenny and Chanock, Stephen J and Chirlaque, Maria-Dolores and Cho, Sang Hee and Connolly, Charles M and Cross, Amanda J and Cuk, Katarina and Curtis, Keith R and de la Chapelle, Albert and Doheny, Kimberly F and Duggan, David and Easton, Douglas F and Elias, Sjoerd G and Elliott, Faye and English, Dallas R and Feskens, Edith J. M and Figueiredo, Jane C and Fischer, Rocky and FitzGerald, Liesel M and Forman, David and Gala, Manish and Gallinger, Steven and Gauderman, W. James and Giles, Graham G and Gillanders, Elizabeth and Gong, Jian and Goodman, Phyllis J and Grady, William M and Grove, John S and Gsur, Andrea and Gunter, Marc J and Haile, Robert W and Hampe, Jochen and Hampel, Heather and Harlid, Sophia and Hayes, Richard B and Hofer, Philipp and Hoffmeister, Michael and Hopper, John L and Hsu, Wan-Ling and Huang, Wen-Yi and Hudson, Thomas J and Hunter, David J and Ibañez-Sanz, Gemma and Idos, Gregory E and Ingersoll, Roxann and Jackson, Rebecca D and Jacobs, Eric J and Jenkins, Mark A and Joshi, Amit D and Joshu, Corinne E and Keku, Temitope O and Key, Timothy J and Kim, Hyeong Rok and Kobayashi, Emiko and Kolonel, Laurence N and Kooperberg, Charles and Kühn, Tilman and Küry, Sébastien and ... and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
Nature Genetics, ISSN 1061-4036, 01/2019, Volume 51, Issue 1, pp. 76 - 87
Journal Article
by Jiang, Xia and Jiang, Xia and Finucane, Hilary K and Finucane, Hilary K and Schumacher, Fredrick R and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Tyrer, Jonathan P and Han, Younghun and Han, Younghun and Michailidou, Kyriaki and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Aldrich, Melinda C and Andrew, Angeline S and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Anton-Culver, Hoda and Antoniou, Antonis C and Antoniou, Antonis C and Antonenkova, Natalia N and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Aronson, Kristan J and Arun, Banu K and Arun, Banu K and Bandera, Elisa V and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benitez, Javier and Benlloch, Sara and Benlloch, Sara and Berchuck, Andrew and Berchuck, Andrew and Berndt, Sonja I and Bickeböller, Heike and Bien, Stephanie A and Bien, Stephanie A and Blomqvist, Carl and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brenton, James D and Brook, Mark N and Brook, Mark N and Brunet, Joan and Brunet, Joan and Brunnström, Hans and Buchanan, Daniel D and Buchanan, Daniel D and Burwinkel, Barbara and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldés, Trinidad and Caldés, Trinidad and Caligo, Maria A and Caligo, Maria A and Campbell, Ian and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Géraldine and Cancel-Tassin, Géraldine and Cannon-Albright, Lisa and Cannon-Albright, Lisa and Campa, Daniele and Campa, Daniele and Caporaso, Neil and Carvalho, André L and Carvalho, André L and Chan, Andrew T and Chan, Andrew T and Chang-Claude, Jenny and Chang-Claude, Jenny and Chanock, Stephen J and Chanock, Stephen J and Chen, Chu and ... and Medicinska fakulteten and Klinisk kemi and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 431 - 23
Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association... 
BREAST-CANCER | LUNG-CANCER | RISK-FACTORS | PARTITIONING HERITABILITY | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | GENETIC ARCHITECTURE | ANALYSES IDENTIFY | MENDELIAN RANDOMIZATION | CELL-TYPES | GENOME-WIDE ASSOCIATION | Lung Neoplasms - ethnology | Colorectal Neoplasms - genetics | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Prostatic Neoplasms - diagnosis | Case-Control Studies | Colorectal Neoplasms - diagnosis | Ovarian Neoplasms - ethnology | Inheritance Patterns | Ovarian Neoplasms - genetics | Mental Disorders - genetics | Prostatic Neoplasms - genetics | Smoking - physiopathology | Head and Neck Neoplasms - ethnology | Female | Neoplasm Proteins - genetics | Breast Neoplasms - ethnology | Lung Neoplasms - genetics | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Colorectal Neoplasms - ethnology | Ovarian Neoplasms - diagnosis | European Continental Ancestry Group | Smoking - genetics | Prostatic Neoplasms - ethnology | Head and Neck Neoplasms - pathology | Mental Disorders - physiopathology | Smoking - ethnology | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Head and Neck Neoplasms - diagnosis | Head and Neck Neoplasms - genetics | Breast Neoplasms - diagnosis | Mental Disorders - ethnology | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | Lung Neoplasms - diagnosis | Enrichment | Correlation | Statistical analysis | Ovarian carcinoma | Mental disorders | Lung cancer | Colorectal carcinoma | Genomes | Breast cancer | Regulatory sequences | Ovarian cancer | Etiology | Breast | Heritability | Neck | Solid tumors | Prostate cancer | Prostate | Cancer | Smoking | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Jiang, Xia and Finucane, Hilary K and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Han, Younghun and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Antoniou, Antonis C and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Arun, Banu K and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benlloch, Sara and Berchuck, Andrew and Berndt, Sonja I and Bickeböller, Heike and Bien, Stephanie A and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brook, Mark N and Brunet, Joan and Brunnström, Hans and Buchanan, Daniel D and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldés, Trinidad and Caligo, Maria A and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Géraldine and Cannon-Albright, Lisa and Campa, Daniele and Caporaso, Neil and Carvalho, André L and Chan, Andrew T and Chang-Claude, Jenny and Chanock, Stephen J and Chen, Chu and Christiani, David C and Claes, Kathleen B. M and Claessens, Frank and Clements, Judith and Collée, J. Margriet and Correa, Marcia Cruz and Couch, Fergus J and Cox, Angela and Cunningham, Julie M and Cybulski, Cezary and Czene, Kamila and Daly, Mary B and deFazio, Anna and Devilee, Peter and Diez, Orland and Gago-Dominguez, Manuela and Donovan, Jenny L and Dörk, Thilo and Duell, Eric J and Dunning, Alison M and Dwek, Miriam and Eccles, Diana M and Edlund, Christopher K and Edwards, Digna R. Velez and Ellberg, Carolina and Evans, D. Gareth and Fasching, Peter A and Ferris, Robert L and Liloglou, Triantafillos and Figueiredo, Jane C and Fletcher, Olivia and Fortner, Renée T and Fostira, Florentia and Franceschi, Silvia and Friedman, Eitan and Gallinger, Steven J and Ganz, Patricia A and ...
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 8
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Heritability
Journal Article
Journal Article
by Bien, Stephanie A and Su, Yu-Ru and Conti, David V and Harrison, Tabitha A and Qu, Conghui and Guo, Xingyi and Lu, Yingchang and Albanes, Demetrius and Auer, Paul L and Banbury, Barbara L and Berndt, Sonja I and Bézieau, Stéphane and Brenner, Hermann and Buchanan, Daniel D and Caan, Bette J and Campbell, Peter T and Carlson, Christopher S and Chan, Andrew T and Chang-Claude, Jenny and Chen, Sai and Connolly, Charles M and Easton, Douglas F and Feskens, Edith J M and Gallinger, Steven and Giles, Graham G and Gunter, Marc J and Hampe, Jochen and Huyghe, Jeroen R and Hoffmeister, Michael and Hudson, Thomas J and Jacobs, Eric J and Jenkins, Mark A and Kampman, Ellen and Kang, Hyun Min and Kühn, Tilman and Küry, Sébastien and Lejbkowicz, Flavio and Le Marchand, Loic and Milne, Roger L and Li, Li and Li, Christopher I and Lindblom, Annika and Lindor, Noralane M and Martín, Vicente and McNeil, Caroline E and Melas, Marilena and Moreno, Victor and Newcomb, Polly A and Offit, Kenneth and Pharaoh, Paul D P and Potter, John D and Qu, Chenxu and Riboli, Elio and Rennert, Gad and Sala, Núria and Schafmayer, Clemens and Scacheri, Peter C and Schmit, Stephanie L and Severi, Gianluca and Slattery, Martha L and Smith, Joshua D and Trichopoulou, Antonia and Tumino, Rosario and Ulrich, Cornelia M and van Duijnhoven, Fränzel J B and Van Guelpen, Bethany and Weinstein, Stephanie J and White, Emily and Wolk, Alicja and Woods, Michael O and Wu, Anna H and Abeçasis, Goncalo R and Casey, Graham and Nickerson, Deborah A and Gruber, Stephen B and Hsu, Li and Zheng, Wei and Peters, Ulrike
Human genetics, ISSN 0340-6717, 07/2019, Volume 138, Issue 7, pp. 789 - 791
Journal Article
by Huyghe, Jeroen R and Bien, Stephanie A and Harrison, Tabitha A and Kang, Hyun Min and Chen, Sai and Schmit, Stephanie L and Conti, David V and Qu, Conghui and Jeon, Jihyoun and Edlund, Christopher K and Greenside, Peyton and Wainberg, Michael and Schumacher, Fredrick R and Smith, Joshua D and Levine, David M and Nelson, Sarah C and Sinnott-Armstrong, Nasa A and Albanes, Demetrius and Alonso, M Henar and Anderson, Kristin and Arnau-Collell, Coral and Arndt, Volker and Bamia, Christina and Banbury, Barbara L and Baron, John A and Berndt, Sonja I and Bézieau, Stéphane and Bishop, D Timothy and Boehm, Juergen and Boeing, Heiner and Brenner, Hermann and Brezina, Stefanie and Buch, Stephan and Buchanan, Daniel D and Burnett-Hartman, Andrea and Butterbach, Katja and Caan, Bette J and Campbell, Peter T and Carlson, Christopher S and Castellví-Bel, Sergi and Chan, Andrew T and Chang-Claude, Jenny and Chanock, Stephen J and Chirlaque, Maria-Dolores and Cho, Sang Hee and Connolly, Charles M and Cross, Amanda J and Cuk, Katarina and Curtis, Keith R and de la Chapelle, Albert and Doheny, Kimberly F and Duggan, David and Easton, Douglas Frederick and Elias, Sjoerd G and Elliott, Faye and English, Dallas R and Feskens, Edith JM and Figueiredo, Jane C and Fischer, Rocky and FitzGerald, Liesel M and Forman, David and Gala, Manish and Gallinger, Steven and Gauderman, W James and Giles, Graham G and Gillanders, Elizabeth and Gong, Jian and Goodman, Phyllis J and Grady, William M and Grove, John S and Gsur, Andrea and Gunter, Marc J and Haile, Robert W and Hampe, Jochen and Hampel, Heather and Harlid, Sophia and Hayes, Richard B and Hofer, Philipp and Hoffmeister, Michael and Hopper, John L and Hsu, Wan-Ling and Huang, Wen-Yi and Hudson, Thomas J and Hunter, David J and Ibañez-Sanz, Gemma and Idos, Gregory E and Ingersoll, Roxann and Jackson, Rebecca D and Jacobs, Eric J and Jenkins, Mark A and Joshi, Amit D and Joshu, Corinne E and Keku, Temitope O and Key, Timothy J and Kim, Hyeong Rok and Kobayashi, Emiko and Kolonel, Laurence N and Kooperberg, Charles and Kühn, Tilman and Küry, Sébastien and ... and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature Genetics, ISSN 1061-4036, 2019, Volume 51, Issue 1, p. 76
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed... 
Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Bien, Stephanie A and Su, Yu-Ru and Conti, David V and Harrison, Tabitha A and Qu, Conghui and Guo, Xingyi and Lu, Yingchang and Albanes, Demetrius and Auer, Paul L and Banbury, Barbara L and Berndt, Sonja I and Bézieau, Stéphane and Brenner, Hermann and Buchanan, Daniel D and Caan, Bette J and Campbell, Peter T and Carlson, Christopher S and Chan, Andrew T and Chang-Claude, Jenny and Chen, Sai and Connolly, Charles M and Easton, Douglas F and Feskens, Edith J. M and Gallinger, Steven and Giles, Graham G and Gunter, Marc J and Hampe, Jochen and Huyghe, Jeroen R and Hoffmeister, Michael and Hudson, Thomas J and Jacobs, Eric J and Jenkins, Mark A and Kampman, Ellen and Kang, Hyun Min and Kühn, Tilman and Küry, Sébastien and Lejbkowicz, Flavio and Le Marchand, Loic and Milne, Roger L and Li, Li and Li, Christopher I and Lindblom, Annika and Lindor, Noralane M and Martín, Vicente and McNeil, Caroline E and Melas, Marilena and Moreno, Victor and Newcomb, Polly A and Offit, Kenneth and Pharaoh, Paul D. P and Potter, John D and Qu, Chenxu and Riboli, Elio and Rennert, Gad and Sala, Núria and Schafmayer, Clemens and Scacheri, Peter C and Schmit, Stephanie L and Severi, Gianluca and Slattery, Martha L and Smith, Joshua D and Trichopoulou, Antonia and Tumino, Rosario and Ulrich, Cornelia M and van Duijnhoven, Fränzel J. B and Van Guelpen, Bethany and Weinstein, Stephanie J and White, Emily and Wolk, Alicja and Woods, Michael O and Wu, Anna H and Abecasis, Goncalo R and Casey, Graham and Nickerson, Deborah A and Gruber, Stephen B and Hsu, Li and Zheng, Wei and Peters, Ulrike and Medicinska fakulteten and Patologi and Institutionen för medicinsk biovetenskap and Umeå universitet
Human Genetics, ISSN 0340-6717, 04/2019, Volume 138, Issue 4, pp. 307 - 326
Genome-wide association studies have reported 56 independently associated colorectal cancer (CRC) risk variants, most of which are non-coding and believed to... 
CELLS | METAANALYSIS | GLYCOGEN-PHOSPHORYLASE | GENOTYPE IMPUTATION | TRIPARTITE MOTIF | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | HYDROGEN-PEROXIDE | COLON | IDENTIFICATION | GENOME-WIDE ASSOCIATION | Colorectal Neoplasms - epidemiology | Predictive Value of Tests | Gene Expression | Genetic Predisposition to Disease | Prognosis | Colorectal Neoplasms - genetics | Gene Frequency | Humans | Risk Factors | Gene Expression Regulation, Neoplastic | Genome-Wide Association Study - statistics & numerical data | Case-Control Studies | Colorectal Neoplasms - diagnosis | Polymorphism, Single Nucleotide | Medical colleges | Oncology, Experimental | Genes | Genomics | Colorectal cancer | Genomes | Research | Gene expression | Risk factors | Genetic research | Genetic aspects | Health aspects | Cancer | Statistical analysis | CXCR2 protein | Therapeutic applications | Colorectal carcinoma | Homeostasis | Chromosome 2 | Genetic variance | Computer applications | Replication | Colon | Tumors | Original Investigation | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Nutrition and Disease | HNE Voeding en Gezondheid in de Levenscyclus | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | HNE Nutrition and Disease | Wereldvoeding | Chair Nutrition and Disease | Voeding en Ziekte | HNE Nutrition and Health over the Lifecourse | HNE Voeding en Ziekte
Journal Article
by Fanidi, Anouar and Carreras‐Torres, Robert and Larose, Tricia L and Yuan, Jian‐Min and Stevens, Victoria L and Weinstein, Stephanie J and Albanes, Demetrius and Prentice, Ross and Pettinger, Mary and Cai, Qiuyin and Blot, William J and Arslan, Alan A and Zeleniuch‐Jacquotte, Anne and McCullough, Marjorie L and Le Marchand, Loic and Wilkens, Lynne R and Haiman, Christopher A and Zhang, Xuehong and Stampfer, Meir J and Smith‐Warner, Stephanie A and Giovannucci, Edward and Giles, Graham G and Hodge, Allison M and Severi, Gianluca and Johansson, Mikael and Grankvist, Kjell and Langhammer, Arnulf and Brumpton, Ben M and Wang, Renwei and Gao, Yu‐Tang and Ericson, Ulrika and Bojesen, Stig E and Arnold, Susanne M and Koh, Woon‐Puay and Shu, Xiao‐Ou and Xiang, Yong‐Bing and Li, Honglan and Zheng, Wei and Lan, Qing and Visvanathan, Kala and Hoffman‐Bolton, Judith and Ueland, Per M and Midttun, Øivind and Caporaso, Neil E and Purdue, Mark and Freedman, Neal D and Buring, Julie E and Lee, I‐Min and Sesso, Howard D and Michael Gaziano, J and Manjer, Jonas and Relton, Caroline L and Hung, Rayjean J and Amos, Chris I and Johansson, Mattias and Brennan, Paul and LC3 Consortium and TRICL Consortium and LC3 consortium and the TRICL consortium and on behalf of the LC3 consortium and the TRICL consortium and Medicinska fakulteten and Klinisk kemi and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
International Journal of Cancer, ISSN 0020-7136, 09/2019, Volume 145, Issue 6, pp. 1499 - 1503
Journal Article