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FEBS Journal, ISSN 1742-464X, 07/2015, Volume 282, Issue 14, p. 2587
  The transmembrane protease complex [gamma]-secretase is a key enzyme in Alzheimer disease pathogenesis as it liberates the neurotoxic amyloid [beta]-peptide... 
Proteins | Brain | Neurons | Alzheimer's disease | Enzymes | Alzheimers disease
Journal Article
FEBS Journal, ISSN 1742-464X, 09/2015, Volume 282, Issue 17, p. 3438
  [gamma]-Secretase is a transmembrane protease complex that is responsible for the processing of a multitude of type 1 transmembrane proteins, including the... 
Inositol | Proteases | Amyloid beta-protein | Genetic engineering | Alzheimer's disease | Adenosine triphosphatase | Membrane proteins | Proteins | Alzheimers disease | Rodents
Journal Article
Journal Article
Acta Neuropathologica Communications, 01/2016, Volume 4
  The transmembrane protein assembly [gamma]-secretase is a key protease in regulated intramembrane processing (RIP) of around 100 type-1 transmembrane... 
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, p. P682
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P682 - P682
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P1041 - P1042
Journal Article
Alzheimer's Research and Therapy, ISSN 1758-9193, 08/2017, Volume 9, Issue 1, pp. 57 - 19
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63962
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 12/2015, Volume 52, Issue 3, pp. 1077 - 1092
Dysfunctional Omi/HtrA2, a mitochondrial serine protease, has been implicated in various neurodegenerative disorders. Despite the wealth of evidence on the... 
Vimentin | Neurology | Neurosciences | Mitochondria | APP swe | Biomedicine | Alzheimer disease | Neurobiology | Human primary neurons | Omi/HtrA2 | Cell Biology | APP | OUTER-MEMBRANE | APOPTOSIS | APP(swe) | NEUROPROTECTIVE ROLE | AMYLOID PRECURSOR PROTEIN | NEUROSCIENCES | HUMAN HTRA2 | SERINE-PROTEASE | INTERMEDIATE-FILAMENTS | IN-SITU | PARKINSONS-DISEASE | Vimentin - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Mutation, Missense | Neoplasm Proteins - metabolism | Cytosol - enzymology | Isothiocyanates - toxicity | Neurons - ultrastructure | Transfection | Mitochondrial Proteins - metabolism | Amyloid beta-Protein Precursor - metabolism | Axons - ultrastructure | Interleukin-1beta - toxicity | Pyrimidinones - pharmacology | Neurogenesis - drug effects | Neurons - metabolism | Culture Media, Serum-Free - pharmacology | Neurons - drug effects | Neuroblastoma - pathology | Serine Proteinase Inhibitors - pharmacology | Tretinoin - pharmacology | Stress, Physiological - physiology | Nerve Tissue Proteins - antagonists & inhibitors | Tunicamycin - toxicity | Mitochondrial Proteins - antagonists & inhibitors | High-Temperature Requirement A Serine Peptidase 2 | Nerve Tissue Proteins - metabolism | Point Mutation | Amyloid beta-Protein Precursor - genetics | Intermediate Filaments - ultrastructure | Cell Line, Tumor | Serine Endopeptidases - metabolism | Thiones - pharmacology | Mitochondria - physiology | Nervous system diseases | Neurons | Analysis | Amyloid beta-protein | Thrombin | Mitochondrial DNA | Neuroblastoma | Intermediate filament proteins | Alzheimer's disease | Neurophysiology | Proteases | Stress | Cells
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2011, Volume 6, Issue 12, p. e29011
Protein C inhibitor (PCI) is a serpin type of serine protease inhibitor that is found in many tissues and fluids in human, including blood plasma, seminal... 
SERPIN | KALLIKREIN | COMPLEX | MECHANISM | PROSTATE-SPECIFIC ANTIGEN | SEMINAL PLASMA | BIOLOGY | HUMAN SEMEN | INFERTILITY | ANTITHROMBIN | BINDING | Protein C Inhibitor - blood | Humans | Gene Expression Regulation | Models, Molecular | Male | Organ Specificity | Polysaccharides | Semen - metabolism | Prostate-Specific Antigen - antagonists & inhibitors | Protein Conformation | Prostate-Specific Antigen - metabolism | Prostate-Specific Antigen - chemistry | Protein C Inhibitor - pharmacology | Protein C Inhibitor - chemistry | Protein C Inhibitor - metabolism | Protease inhibitors | Prostate-specific antigen | Thrombin | Protein C | Mass spectrometry | Prostate cancer | Neurosciences | Rate constants | Serine | Childrens health | Serpins | Amino acids | Biochemistry | Tissues | Males | Crystallography | Blood | Blood plasma | Proteins | Protease | Catalysis | Inhibition | Urine | Antigens | Semen | Mass spectroscopy | Constants | N-glycans | Chromatography | Glycan | Children & youth | Inhibitors | Womens health | Proteomics | Ligands | Serine proteinase | Reproductive system | Prostate | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Biokemi | MEDICINE | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | N-glycosylation | Prostate specific antigen | Medical Biotechnology | Serpin | Chemistry | MEDICIN | Kemi | Protein C inhibitor | Seminal plasma
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e29586
Phagocytotic cells play a fundamental role in the defense against bacterial pathogens. One mechanism whereby bacteria evade phagocytosis is to produce factors... 
NEISSERIA-MENINGITIDIS NHHA | CELLS | INHIBITION | LETHALITY | LYMPHOCYTE | SEROGROUP-B | MITOCHONDRIA | BIOLOGY | SEPSIS | PORIN PORB | IDENTIFICATION | Meningococcal Infections - immunology | Tumor Necrosis Factor-alpha - metabolism | Neisseria meningitidis - metabolism | Apoptosis - drug effects | Monocytes - cytology | Apoptosis - genetics | Bacterial Outer Membrane Proteins - pharmacology | Meningococcal Infections - pathology | Neisseria meningitidis - genetics | Monocytes - physiology | Bacterial Outer Membrane Proteins - genetics | Macrophages - physiology | Nitric Oxide - physiology | Signal Transduction - genetics | Cell Lineage | Macrophages - metabolism | Animals | Bacterial Outer Membrane Proteins - metabolism | Protein Binding | Macrophages - drug effects | Signal Transduction - physiology | Mice | Apoptosis - physiology | Bacterial Outer Membrane Proteins - physiology | Nitric Oxide - metabolism | Heat shock proteins | Meningitis | B cells | Macrophages | Nitric oxide | Apoptosis | Neurosciences | Mucosa | Homeostasis | Homology | Infections | Biochemistry | Proteins | Toxicology | Cell activation | Laminin | E coli | Lymphocytes | Gangrene | Bacteria | Extracellular matrix | Heparan sulfate | Medical research | Bacterial infections | Immunoregulation | Caspase | Exposure | Permeability | Tumor necrosis factor-α | Chromatography | Nitric-oxide synthase | Membrane proteins | Studies | Signaling | Sepsis | Phagocytosis | Meningococcal disease | Basic Medicine | NEISSERIA-MENINGITIDIS NHHA; PORIN PORB; SEROGROUP-B; CELLS; SEPSIS; IDENTIFICATION; MITOCHONDRIA; INHIBITION; LYMPHOCYTE; LETHALITY | Medical and Health Sciences | Microbiology in the medical area | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Mikrobiologi inom det medicinska området
Journal Article