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Current Opinion in Chemical Biology, ISSN 1367-5931, 2010, Volume 14, Issue 4, pp. 447 - 455
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2019, p. 126725
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 08/2015, Volume 23, Issue 16, pp. 5182 - 5189
Visceral leishmaniasis is a neglected parasitic disease that has a high fatality rate in the absence of treatment. New drugs that are inexpensive, orally... 
Neglected disease | Parasitic disease | Quinazoline | Leishmania
Journal Article
Current Opinion in Investigational Drugs, ISSN 1472-4472, 02/2006, Volume 7, Issue 2, pp. 147 - 157
Diamidine-containing compounds have a long history of use in the treatment of African trypanosomiasis and leishmaniasis. The discovery that diamidine prodrugs... 
Diamidine | Trypanosomes | Plasmodium | Chemotherapy | Pentamidine | Leishmania | AFRICAN TRYPANOSOMES | PENTAMIDINE-RESISTANT LEISHMANIA | KINETOPLAST DNA | TRYPANOCIDAL ACTIVITY | chemotherapy | DICATIONIC COMPOUNDS | BIPHENYL BENZIMIDAZOLE DERIVATIVES | MEXICANA-AMAZONENSIS | pentamidine | PARASITE PLASMODIUM-FALCIPARUM | PHARMACOLOGY & PHARMACY | TRYPANOSOMA-BRUCEI-BRUCEI | ANTIPROTOZOAL ACTIVITY | trypanosomes | diamidine | Trypanosomiasis, African - drug therapy | Humans | Pentamidine - therapeutic use | Plasmodium falciparum - drug effects | Trypanosoma brucei gambiense - drug effects | Benzamidines - therapeutic use | Leishmania - drug effects | Trypanocidal Agents - therapeutic use | Benzamidines - metabolism | Drug Evaluation, Preclinical | Pentamidine - pharmacology | Malaria, Falciparum - drug therapy | Trypanosoma brucei gambiense - growth & development | Leishmaniasis - drug therapy | Antimalarials - therapeutic use | Clinical Trials as Topic | Pentamidine - analogs & derivatives | Benzamidines - pharmacology | Antiprotozoal Agents - pharmacology | Antimalarials - pharmacology | Animals | Trypanosoma cruzi - growth & development | Trypanocidal Agents - pharmacology | Chagas Disease - drug therapy | Trypanosoma cruzi - drug effects | Prodrugs - therapeutic use | Plasmodium falciparum - growth & development | Antiprotozoal Agents - therapeutic use | Leishmania - growth & development | Prodrugs - pharmacology
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2014, Volume 57, Issue 12, pp. 5141 - 5156
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2015, Volume 23, Issue 16, p. 5182
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Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2018, Volume 62, Issue 1
Given the limitations of current antileishmanial drugs and the utility of oral combination therapy for other infections, developing an oral combination against... 
Chemotherapy | DB766 | Posaconazole | Leishmania | posaconazole | VITRO | IN-VIVO EFFICACY | MICROBIOLOGY | CALCINEURIN INHIBITORS | chemotherapy | CANDIDA-ALBICANS | EXPERIMENTAL VISCERAL LEISHMANIASIS | PHARMACOLOGY & PHARMACY | EXPERIMENTAL-DESIGN | N-2,N-4-DISUBSTITUTED QUINAZOLINE-2,4-DIAMINES | DRUG-COMBINATION | BIS-ARYLIMIDAMIDES | FLUCONAZOLE
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2015, Volume 23, Issue 16, pp. 5182 - 5189
Visceral leishmaniasis is a neglected parasitic disease that has a high fatality rate in the absence of treatment. New drugs that are inexpensive, orally... 
Neglected disease | Parasitic disease | Quinazoline | Leishmania
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2012, Volume 56, Issue 5, pp. 2428 - 2434
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2016, Volume 59, Issue 2, pp. 775 - 775
Journal Article
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