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Clinical Cancer Research, ISSN 1078-0432, 08/2016, Volume 22, Issue 16 Supplement, pp. IA11 - IA11
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2018, Volume 24, Issue 8, pp. 1246 - 1256
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e17038 - e17038
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e17039 - e17039
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6314 - 9
As patient derived xenograft (PDX) models are increasingly used for preclinical drug development, strategies to account for the nonhuman component of PDX RNA... 
BREAST-CANCER | MODELS | SUBTYPES | MULTIDISCIPLINARY SCIENCES | ENRICHMENT ANALYSIS | MAINTENANCE THERAPY | NIRAPARIB | Animal models | Transcription | Xenografts | Stroma | Gene expression | Drug development | Bioinformatics | Patients | Ovarian cancer | Tumors
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 2014, Volume 20, Issue 5, pp. 1288 - 1297
Journal Article
Cancer Research, ISSN 0008-5472, 12/2017, Volume 77, Issue 23, pp. 6524 - 6537
E26 transformation-specific transcription factor ERG is aberrantly overexpressed in approximately 50% of all human prostate cancer due to TMPRSS2-ERG gene... 
CANCER-CELLS | CYTOSOLIC FOXO1 | ANDROGEN RECEPTOR | GENE FUSIONS | ONCOLOGY | PHOSPHORYLATION | PTEN | DEGRADATION | ERG | EXPRESSION | FORKHEAD TRANSCRIPTION FACTORS | Prostatic Neoplasms - pathology | RNA, Small Interfering - genetics | Cell Proliferation - genetics | Prostatic Intraepithelial Neoplasia - pathology | Serine Endopeptidases - biosynthesis | Humans | Male | Mice, Transgenic | Transcriptional Regulator ERG - biosynthesis | Prostate - pathology | Animals | Prostatic Neoplasms - genetics | RNA Interference | Cell Transformation, Neoplastic - genetics | Serine Endopeptidases - genetics | Cell Line, Tumor | Mice | Prostatic Intraepithelial Neoplasia - genetics | Transcription, Genetic - genetics | Transcriptional Regulator ERG - genetics | Neoplasm Invasiveness - genetics | Forkhead Box Protein O1 - genetics | Cell proliferation | ERG protein | Transformation | Transcription factors | Gene deletion | Proteins | Signal transduction | Clonal deletion | FOXO1 protein | Etiology | Deletion | FOXO4 protein | Forkhead protein | Tumorigenesis | Lesions | FOXO3 protein | Transgenic mice | Gene expression | Disease control | ERG gene | Signaling | Androgens | Tumor suppressor genes | Prostatic intraepithelial neoplasia | Aberration | Prostate cancer | Prostate | Cancer | prostate cancer | PIN | TMPRSS2-ERG | tumorigenesis | cell invasion | FoxO1
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11153 - 13
Although 70-80% of newly diagnosed ovarian cancer patients respond to first-line therapy, almost all relapse and five-year survival remains below 50%. One... 
CHEMOSENSITIVITY | GLIOBLASTOMA | MULTIDISCIPLINARY SCIENCES | CA-125 | SENSITIVITY | RESISTANCE | RECURRENCE | MECHANISMS | CHEMORESPONSE ASSAY | CHEMOTHERAPY | PROGRESSION | Cell culture | Chemotherapy | Biopsy | Tissue culture | Population studies | Laparoscopy | Health risk assessment | Patients | Cancer therapies | Ovarian cancer
Journal Article
Cancer Cell, ISSN 1535-6108, 09/2017, Volume 32, Issue 3, pp. 310 - 323.e5
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0126867
Ovarian carcinosarcoma is a rare subtype of ovarian cancer with poor clinical outcomes. The low incidence of this disease makes accrual to large clinical... 
CARCINOMA XENOGRAFTS | BREAST-CANCER | MODELS | UTERINE CARCINOSARCOMA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | CLINICAL-TRIALS | PLATINUM-BASED CHEMOTHERAPY | MIXED MESODERMAL TUMORS | MULLERIAN TUMORS | INHIBITOR | Paclitaxel - pharmacology | Humans | Ovarian Neoplasms - pathology | Gene Expression Profiling | Antineoplastic Agents - administration & dosage | Molecular Targeted Therapy | Ovarian Neoplasms - genetics | Female | Antineoplastic Agents - pharmacology | Ovarian Neoplasms - metabolism | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Disease Models, Animal | Carcinosarcoma - pathology | Carcinosarcoma - metabolism | Carboplatin - administration & dosage | Tumor Burden | Xenograft Model Antitumor Assays | Maximum Tolerated Dose | Animals | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Carcinosarcoma - drug therapy | Carcinosarcoma - genetics | Mice | Carboplatin - pharmacology | Chemotherapy | Usage | Physiological aspects | Genetic aspects | Research | Drug therapy | Cancer | Ovarian cancer | Phosphorylation | Ovarian carcinoma | p53 Protein | Lung cancer | Clinical trials | Cytotoxicity | Oncology | mRNA | Insulin-like growth factors | Hybridization | ADP | Cancer therapies | K-Ras protein | Model matching | Ribose | Paclitaxel | Xenografts | Vascular endothelial growth factor | Medical research | Epidermal growth factor receptors | Ifosfamide | Breast cancer | Insulin | Patients | Studies | Amplification | Polymerase | Gene amplification | Inhibitors | Carboplatin | Mutation | Laboratory animals | Tumors
Journal Article