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Journal Article
Future oncology (London, England), 02/2017, Volume 13, Issue 3, p. 263
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 24, pp. 8895 - 8900
Journal Article
Science, ISSN 0036-8075, 2/2004, Volume 303, Issue 5660, pp. 983 - 988
The structure of the general transcription factor IIB (TFIIB) in a complex with RNA polymerase II reveals three features crucial for transcription initiation:... 
Yeasts | Docks | RNA | DNA | TATA box | Transcription initiation site | Promoter regions | Research Articles | Hybridity | General transcription factors | Zinc | START SITE SELECTION | ANGSTROM RESOLUTION | PROTEIN INTERACTIONS | ELONGATION COMPLEX | MULTIDISCIPLINARY SCIENCES | FUNCTIONAL DOMAINS | ZINC RIBBON | PREINITIATION COMPLEX | SACCHAROMYCES-CEREVISIAE | INITIATION COMPLEX | N-TERMINAL REGION | Transcription Factor TFIIB - metabolism | Transcription Factor TFIIB - chemistry | Molecular Sequence Data | Templates, Genetic | Crystallography, X-Ray | RNA Polymerase II - metabolism | Zinc - chemistry | TATA-Box Binding Protein - metabolism | Nuclear Magnetic Resonance, Biomolecular | Transcription, Genetic | TATA-Box Binding Protein - chemistry | Binding Sites | RNA Polymerase II - chemistry | RNA - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Promoter Regions, Genetic | Nucleic Acid Hybridization | Protein Structure, Secondary | Crystallization | Models, Molecular | DNA - metabolism | RNA - chemistry | Transcription Factors, TFII - chemistry | DNA - chemistry | Saccharomyces cerevisiae Proteins - metabolism | TATA Box | Transcription Factors, TFII - metabolism | Protein Conformation | Saccharomyces cerevisiae Proteins - chemistry | Models | Chemical properties | Genetic transcription | RNA polymerases | Genetics | RNA polymerase | TFIIH protein | TFIIE protein | TFIIB protein | TFIIF protein | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2019, p. jbc.RA119.009131
RAS  regulation and signaling are largely accomplished by direct protein-protein interactions, making RAS protein dynamics a critical determinant of RAS... 
Index Medicus
Journal Article
Nature chemical biology, ISSN 1552-4450, 12/2014, Volume 10, Issue 12, pp. 1006 - 1012
Her3 (also known as ErbB3) belongs to the epidermal growth factor receptor tyrosine kinases and is well credentialed as an anti-cancer target but is thought to... 
ADJUVANT CHEMOTHERAPY | LUNG-CANCER | DOMAIN | PROTEIN | MET AMPLIFICATION | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELECTIVE INHIBITORS | EXTENDED 5-SUBSTITUENT | OVARIAN-CANCER | HER2-POSITIVE BREAST-CANCER | Proto-Oncogene Proteins c-met - metabolism | Adenine - chemical synthesis | Receptor, ErbB-2 - genetics | Antineoplastic Agents - chemical synthesis | Humans | Protein Multimerization | Receptor, ErbB-2 - chemistry | Gene Expression Regulation, Neoplastic | Receptor, ErbB-2 - metabolism | Molecular Targeted Therapy | Receptor, ErbB-3 - chemistry | Proteolysis | Adenosine Triphosphate - metabolism | Antineoplastic Agents - pharmacology | Acrylamides - pharmacology | Protein Kinase Inhibitors - chemical synthesis | Catalytic Domain | Adenine - analogs & derivatives | Signal Transduction | Receptor, ErbB-3 - antagonists & inhibitors | Adenine - pharmacology | Cysteine - chemistry | Receptor, ErbB-3 - genetics | Proto-Oncogene Proteins c-met - genetics | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Cell Proliferation - drug effects | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Adamantane - chemistry | Proto-Oncogene Proteins c-met - chemistry | Adenosine Triphosphate - chemistry | Acrylamides - chemical synthesis | Signal transduction | Cell growth | Phosphorylation | Pharmacology | Epidermal growth factor | Kinases | Index Medicus
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 06/2016, Volume 12, Issue 6, pp. 452 - 458
Journal Article