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science & technology (18) 18
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hiv-1 - immunology (12) 12
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1. Full Text Antibody Specificities Associated with Neutralization Breadth in Plasma from Human Immunodeficiency Virus Type 1 Subtype C-Infected Blood Donors
by Elin S. Gray and Natasha Taylor and Diane Wycuff and Penny L. Moore and Georgia D. Tomaras and Constantinos Kurt Wibmer and Adrian Puren and Allan DeCamp and Peter B. Gilbert and Blake Wood and David C. Montefiori and James M. Binley and George M. Shaw and Barton F. Haynes and John R. Mascola and Lynn Morris
Journal of Virology, ISSN 0022-538X, 09/2009, Volume 83, Issue 17, pp. 8925 - 8937
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Cross Reactions | HIV Antibodies - blood | Antibody Specificity | Blood Donors | Epitope Mapping | HIV-1 - immunology | Humans | Neutralization Tests | Antibodies, Anticardiolipin - blood | Index Medicus | Pathogenesis and Immunity
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2. Full Text The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection
by Elin S. Gray and Maphuti C. Madiga and Tandile Hermanus and Penny L. Moore and Constantinos Kurt Wibmer and Nancy L. Tumba and Lise Werner and Koleka Mlisana and Sengeziwe Sibeko and Carolyn Williamson and Salim S. Abdool Karim and Lynn Morris and and the CAPRISA002 Study Team and CAPRISA 002 Acute Infection Study Team and CAPRISA002 Study Team and and the CAPRISA002 Study Team
Journal of Virology, ISSN 0022-538X, 05/2011, Volume 85, Issue 10, pp. 4828 - 4840
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | HIV Antibodies - blood | Epitope Mapping | HIV Infections - virology | Humans | Viral Load | CD4-Positive T-Lymphocytes - immunology | Cross Reactions | Epitopes - immunology | HIV Infections - immunology | HIV-1 - immunology | Time Factors | Female | CD4-Positive T-Lymphocytes - virology | Antibodies, Neutralizing - blood | Index Medicus | Pathogenesis and Immunity
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3. Full Text Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
by Doria-Rose, Nicole A and Schramm, Chaim A and Gorman, Jason and Moore, Penny L and Bhiman, Jinal N and Dekosky, Brandon J and Ernandes, Michael J and Georgiev, Ivelin S and Kim, Helen J and Pancera, Marie and Staupe, Ryan P and Altae-Tran, Han R and Bailer, Robert T and Crooks, Ema T and Cupo, Albert and z, Aliaksan and Garrett, Nigel J and Hoi, Kam H and Kong, Rui and Louder, Mark K and Longo, Nancy S and McKee, Krisha and Nonyane, Molati and O'Dell, Sijy and Roark, Ryan S and Rudicell, Rebecca S and Schmidt, Stephen D and Sheward, Daniel J and Soto, Cinque and Wibmer, Constantinos Kurt and Yang, Yongping and Zhang, Zhenhai and Mullikin, James C and Binley, James M and Sanders, Rogier W and Wilson, Ian A and Moore, John P and Ward, Anew B and Georgiou, George and Williamson, Carolyn and Abdool Karim, Salim S and Morris, Lynn and Kwong, Peter D and Shapiro, Lawrence and Mascola, John R and Becker, Jesse and Benjamin, Betty and Blakesley, Robert and Bouffard, Gerry and Brooks, Shelise and Coleman, Holly and Dekhtyar, Mila and Gregory, Michael and Guan, Xiaobin and Gupta, Jyoti and Han, Joel and Hargrove, April and Ho, Shi-ling and Johnson, Taccara and Legaspi, Richelle and Lovett, Sean and Maduro, Quino and Masiello, Cathy and Maskeri, Baishali and McDowell, Jenny and Montemayor, Casana and Mullikin, James and Park, Morgan and Riebow, Nancy and Schandler, Karen and Schmidt, Brian and Sison, Christina and Stantripop, Mal and Thomas, James and Thomas, Pam and Vemulapalli, Meg and Young, Alice and NISC Comparative Sequencing and NISC Comparative Sequencing Program
Nature (London), ISSN 0028-0836, 2014, Volume 509, Issue 7498, pp. 55 - 62
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Complementarity Determining Regions - genetics | Epitope Mapping | Epitopes, B-Lymphocyte - chemistry | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Antibody Affinity - immunology | Neutralization Tests | Epitopes, B-Lymphocyte - immunology | HIV Antibodies - isolation & purification | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | HIV Envelope Protein gp160 - chemistry | Complementarity Determining Regions - chemistry | HIV-1 - chemistry | Binding Sites - immunology | B-Lymphocytes - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | CD4 Antigens - immunology | B-Lymphocytes - cytology | Models, Molecular | Antibody Affinity - genetics | Antibodies, Neutralizing - genetics | HIV Antibodies - chemistry | AIDS Vaccines - chemistry | Antibodies, Neutralizing - isolation & purification | Cell Lineage | HIV-1 - immunology | B-Lymphocytes - immunology | Antibodies, Neutralizing - chemistry | Complementarity Determining Regions - immunology | HIV Envelope Protein gp160 - immunology | HIV Antibodies - genetics | Somatic Hypermutation, Immunoglobulin - genetics | CD4 Antigens - metabolism | Evolution, Molecular | Viral antibodies | Antigen-antibody reactions | AIDS vaccines | AIDS (Disease) | Antibodies | Physiological aspects | Research | AIDS research | Cell culture | Genes | Human immunodeficiency virus--HIV | Phylogenetics | Amino acids | Infections | Genomes | Mutation | Index Medicus
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4. Full Text Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions
by Wibmer, Constantinos Kurt and Richardson, Simone I and Yolitz, Jason and Cicala, Claudia and Arthos, James and Moore, Penny L and Morris, Lynn and Argonne National Lab. (ANL), Argonne, IL (United States)
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4489 - 14
HIV Antibodies - metabolism | HIV-1 - metabolism | Humans | Integrins - chemistry | Receptors, HIV - chemistry | Protein Binding - immunology | Virion - metabolism | HIV Envelope Protein gp120 - metabolism | Integrins - metabolism | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | HIV-1 - immunology | Receptors, HIV - antagonists & inhibitors | HIV Antibodies - immunology | Receptors, HIV - metabolism | Protein Conformation | Epitopes - chemistry | Antibodies, Monoclonal - metabolism | HIV Envelope Protein gp120 - chemistry | Binding Sites | Antibodies, Monoclonal - immunology | Integrins - antagonists & inhibitors | Immunoglobulins | Peptides | Pathogenesis | Blocking antibodies | Antibodies | Trimers | Vaccines | Lymphoid tissue | Human immunodeficiency virus--HIV | Gut-associated lymphoid tissues | Virions | Monoclonal antibodies | Binding sites | Glycoprotein gp120 | Conformation | Index Medicus | X-ray crystallography | HIV infections | antibodies | BASIC BIOLOGICAL SCIENCES | vaccines
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5. Full Text V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity
by van Eeden, Charmaine and Wibmer, Constantinos Kurt and Scheepers, Cathrine and Richardson, Simone I and Nonyane, Molati and Lambson, Bronwen and Mkhize, Nonhlanhla N and Vijayakumar, Balakrishnan and Sheng, Zizhang and Stanfield-Oakley, Sherry and Bhiman, Jinal N and Bekker, Valerie and Hermanus, Tandile and Mabvakure, Batsirai and Ismail, Arshad and Moody, M. Anthony and Wiehe, Kevin and Garrett, Nigel and Karim, Salim Abdool and Dirr, Heini and Fernandes, Manuel A and Sayed, Yasien and Shapiro, Lawrence and Ferrari, Guido and Haynes, Barton F and Moore, Penny L and Morris, Lynn
Cell reports (Cambridge), ISSN 2211-1247, 12/2018, Volume 25, Issue 11, pp. 3123 - 3135.e6
antibody evolution | V2 antibodies | RV144 vaccine response | HIV | ED motif | CH58 | K169 | CAP228 | V2 structure | ADCC | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Amino Acid Sequence | HIV Infections - virology | Humans | AIDS Vaccines - immunology | Antibody-Dependent Cell Cytotoxicity - immunology | Models, Molecular | HIV Antibodies - isolation & purification | HIV Envelope Protein gp120 - metabolism | Immunoglobulin Light Chains - metabolism | Immunoglobulin Light Chains - chemistry | HIV Infections - immunology | Peptides - metabolism | HIV Antibodies - immunology | Alleles | Protein Binding | Lysine - metabolism | HIV Envelope Protein gp120 - chemistry | Tissue Donors | Index Medicus
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6. Full Text Isolation of a Monoclonal Antibody That Targets the Alpha-2 Helix of gp120 and Represents the Initial Autologous Neutralizing-Antibody Response in an HIV-1 Subtype C-Infected Individual
by Elin S. Gray and M. Anthony Moody and Constantinos Kurt Wibmer and Xi Chen and Dawn Marshall and Joshua Amos and Penny L. Moore and Andrew Foulger and Jae-Sung Yu and Bronwen Lambson and Salim Abdool Karim and John Whitesides and Georgia D. Tomaras and Barton F. Haynes and Lynn Morris and Hua-Xin Liao
Journal of Virology, ISSN 0022-538X, 08/2011, Volume 85, Issue 15, pp. 7719 - 7729
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies | Miscellaneous | Microbiology | Cell Line | Enzyme-Linked Immunosorbent Assay | Humans | Models, Molecular | Antibodies, Monoclonal - isolation & purification | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV-1 - immunology | B-Lymphocytes - immunology | Antibodies, Neutralizing - chemistry | Immunologic Memory | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Index Medicus | Pathogenesis and Immunity
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7. Full Text Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals
by Georgia D. Tomaras and James M. Binley and Elin S. Gray and Emma T. Crooks and Keiko Osawa and Penny L. Moore and Nancy Tumba and Tommy Tong and Xiaoying Shen and Nicole L. Yates and Julie Decker and Constantinos Kurt Wibmer and Feng Gao and S. Munir Alam and Philippa Easterbrook and Salim Abdool Karim and Gift Kamanga and John A. Crump and Myron Cohen and George M. Shaw and John R. Mascola and Barton F. Haynes and David C. Montefiori and Lynn Morris
Journal of Virology, ISSN 0022-538X, 11/2011, Volume 85, Issue 21, pp. 11502 - 11519
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | HIV Antibodies - blood | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | HIV-1 - immunology | B-Lymphocytes - immunology | HIV Envelope Protein gp41 - immunology | Humans | Epitopes, B-Lymphocyte - immunology | Antibodies, Neutralizing - blood | Index Medicus | Pathogenesis and Immunity
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8. Full Text UCLA1, a Synthetic Derivative of a gp120 RNA Aptamer, Inhibits Entry of Human Immunodeficiency Virus Type 1 Subtype C
by Hazel T. Mufhandu and Elin S. Gray and Maphuti C. Madiga and Nancy Tumba and Kabamba B. Alexandre and Thandeka Khoza and Constantinos Kurt Wibmer and Penny L. Moore and Lynn Morris and Makobetsa Khati
Journal of Virology, ISSN 0022-538X, 05/2012, Volume 86, Issue 9, pp. 4989 - 4999
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | HIV Envelope Protein gp120 - genetics | Aptamers, Nucleotide - pharmacology | Aptamers, Nucleotide - toxicity | HIV-1 - drug effects | Humans | Cells, Cultured | HIV Envelope Protein gp120 - antagonists & inhibitors | Models, Molecular | Neutralization Tests | Aptamers, Nucleotide - metabolism | HIV Fusion Inhibitors - pharmacology | HIV-1 - genetics | Virus Internalization - drug effects | Leukocytes, Mononuclear - virology | Dose-Response Relationship, Drug | Drug Synergism | Point Mutation | Protein Binding | Protein Conformation | HIV Envelope Protein gp120 - chemistry | Binding Sites | Index Medicus | Vaccines and Antiviral Agents
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