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Current Opinion in Gastroenterology, ISSN 0267-1379, 11/2019, Volume 35, Issue 6, pp. 499 - 506
PURPOSE OF REVIEWTo describe the latest developments in the field of anti-trafficking agents (ATAs), a class of therapeutics with growing importance in the... 
Viral antibodies | Medical research | Inflammatory bowel diseases | Care and treatment | Usage | Analysis | Clinical trials | Antibodies | Medicine, Experimental
Journal Article
by Gerner, Stefan T and Kuramatsu, Joji B and Sembill, Jochen A and Sprügel, Maximilian I and Endres, Matthias and Haeusler, Karl Georg and Vajkoczy, Peter and Ringleb, Peter A and Purrucker, Jan and Rizos, Timolaos and Erbguth, Frank and Schellinger, Peter D and Fink, Gereon R and Stetefeld, Henning and Schneider, Hauke and Neugebauer, Hermann and Röther, Joachim and Claßen, Joseph and Michalski, Dominik and Dörfler, Arnd and Schwab, Stefan and Huttner, Hagen B and Horn, Markus and Bahner, Dirk and Hagemann, Georg and Rakers, Florian and Endres, Matthias and Haeusler, Karl Georg and Sobesky, Jan and Schurig, Johannes and Zweynert, Sarah and Bauer, Miriam and Vajkoczy, Peter and Fink, Gereon R and Dohmen, Christian and Stetefeld, Henning and Schwarz, Michael and Reimann, Gernot and Reichmann, Heinz and Schneider, Hauke and Rahmig, Jan and Gerner, Stefan T and Kuramatsu, Joji B and Bogenreuther, Christina and Sembill, Jochen A and Sprügel, Maximilian I and Hagen, Manuel and Knappe, Ruben and Köhrmann, Martin and Schwab, Stefan and Huttner, Hagen B and Kloska, Stephan P and Dörfler, Arnd and Ringwald, Jürgen and Hamann, Gerhard F and Röther, Joachim and Michels, Peter and Ringleb, Peter A and Purrucker, Jan and Rizos, Timolaos and Witte, Otto W and Günther, Albrecht and Wöhrle, Johannes C and Alshammari, Fahid and Claßen, Joseph and Michalski, Dominik and Grau, Armin and Palm, Frederick and Urbanek, Christian and Schellinger, Peter D and Glahn, Jörg and Knappe, Ulrich J and Wiendl, Heinz and Fisse, Anna Lena and Minnerup, Jens and Erbguth, Frank and Nueckel, Martin and Bäzner, Hansjörg and Schwert, Henning and Ludolph, Albert Christian and Stösser, Sebastian and Neugebauer, Hermann and Volkmann, Jens and Müllges, Wolfgang and Kraft, Peter and Schubert, Anna‐Lena and RETRACE II German-Wide and RETRACE II (German-Wide Multicenter Analysis of Oral Anticoagulation-Associated Intracerebral Hemorrhage II) Investigators
Annals of Neurology, ISSN 0364-5134, 01/2018, Volume 83, Issue 1, pp. 186 - 196
Journal Article
Nature immunology, ISSN 1529-2908, 03/2019, Volume 20, Issue 4, pp. 514 - 514
In the version of this article initially published, a portion of the Acknowledgements section ("the Clinical Research Group CEDER of the German Research... 
Learning | Memory cells | Immunological memory | Intestine | Lymphocytes | Lymphocytes T | Error correction | CD4 antigen
Journal Article
European Journal of Immunology, ISSN 0014-2980, 12/2017, Volume 47, Issue 12, pp. 2101 - 2112
The IL‐1 family member IL‐36α has proinflammatory and pathogenic properties in psoriasis. IL‐36α binds to the IL‐36 receptor leading to nuclear factor kappa... 
Synovial fibroblasts | B cell | IL‐36R | Plasma cell | MAPK signaling | IL-36R | RHEUMATOID-ARTHRITIS | SURVIVAL | ANTAGONIST IL-36RA | ACTIVATION | BONE-MARROW | HUMAN B-CELLS | IMMUNOLOGY | MATRIX METALLOPROTEINASES | SYNOVIOCYTES | NF-KAPPA-B | EXPRESSION | Interleukin-1 - genetics | NIH 3T3 Cells | Coculture Techniques | Humans | Receptors, Interleukin-1 - genetics | Synovial Membrane - immunology | Gene Expression - immunology | Plasma Cells - metabolism | Cytokines - genetics | Cytokines - immunology | Fibroblasts - metabolism | Cell Line | Interleukin-1 - metabolism | Cytokines - metabolism | Jurkat Cells | Receptors, Interleukin-1 - immunology | Mice, Inbred C57BL | Cells, Cultured | Synovial Membrane - metabolism | Interleukin-1 - pharmacology | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Animals | Fibroblasts - drug effects | Cell Line, Tumor | Fibroblasts - immunology | Mice | Synovial Membrane - cytology | Plasma Cells - immunology | B cells | Psoriasis | Interleukins | Protein kinases | Cell culture | Matrix metalloproteinases | Cytokines | Interleukin | Crosstalk | Stimulation | Inflammation | Kinases | Joint diseases | Synoviocytes | Recruitment | Signaling | Cell activation | Lymphocytes B | Protein kinase | Hsp27 protein | Interleukin 1 | Cell lines | Plasma cells | Fibroblasts
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 1 - 14
Cytokines of the interleukin (IL)-1 family regulate immune and inflammatory responses. The recently discovered IL-36 family members are involved in psoriasis,... 
ACTIVATION | PROTEIN | ANTAGONIST | PARAMETERIZATION | AMYLOID-BETA | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | REGULATORY MOTIF | IDENTIFICATION | NF-KAPPA-B | AGONIST | Nuclear magnetic resonance--NMR | Cytokines | Psoriasis | Lung diseases | Inflammation | Synoviocytes | Signal transduction | Rheumatoid arthritis | Interleukin 1 | N-Terminus | Heme | Transduction | Binding sites
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 9561 - 11
Temporal lobe epilepsy with amygdala enlargement (TLE-AE) is increasingly recognized as a distinct adult electroclinical syndrome. However, functional... 
EXPRESSIONS | DISGUST | LIMBIC ENCEPHALITIS | AROUSAL | INTACT RECOGNITION | MULTIDISCIPLINARY SCIENCES | STIMULI | DAMAGE | BRAIN | Temporal lobe | Amygdala | Immunotherapy | Epilepsy | Cognitive ability | Arousal | Conductance | Anxiety | Patients | Emotions
Journal Article
Inflammatory Bowel Diseases, ISSN 1078-0998, 05/2018, Volume 24, Issue 6, pp. 1237 - 1250
Abstract Background Although anti-adhesion therapies are a novel mainstay in the treatment of inflammatory bowel diseases (IBDs), the mechanisms controlling... 
vedolizumab | etrolizumab | inflammatory bowel diseases | adhesion | gut homing | T cells | natalizumab | Inflammatory bowel diseases | Usage | Lymphocytes | Physiological aspects | Monoclonal antibodies | Drug therapy | Health aspects
Journal Article
Gut, ISSN 0017-5749, 05/2019, p. gutjnl-2018-316772
To study the role of α4β7 integrin for gut homing of monocytes and to explore the biological consequences of therapeutic α4β7 inhibition with regard to... 
Journal Article
Journal of Visualized Experiments, ISSN 1940-087X, 09/2018, Volume 2018, Issue 139
Gut homing of immune cells is important for the pathogenesis of inflammatory bowel diseases (IBD). Integrin-dependent cell adhesion to addressins is a crucial... 
Integrin | Natalizumab | Cell adhesion | Immunology and infection | Gut homing | Addressin | Vedolizumab | Issue 139 | vedolizumab | MADCAM-1 | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | ETROLIZUMAB | ANTIBODY | Immunology and Infection | PHASE-2 | BLOOD-FLOW | MAINTENANCE THERAPY | DIAMETER | INDUCTION THERAPY | addressin | integrin | gut homing | natalizumab
Journal Article
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 12/2006, Volume 77, Issue 12, pp. 1381 - 1382
Journal Article