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Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 1106 - 1106
Abstract Introduction Nephrotic syndrome (NS) is characterized by massive proteinuria (secondary to podocyte injury or dysfunction), hypoalbuminemia, and... 
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2006, Volume 38, Issue 12, pp. 1397 - 1405
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2181 - 2196
Diabetic nephropathy (DN) is among the most lethal complications that occur in type 1 and type 2 diabetics. Podocyte dysfunction is postulated to be a critical... 
EPITHELIAL-MESENCHYMAL TRANSITION | KIDNEY-DISEASE | MAMMALIAN TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | TUBEROUS SCLEROSIS COMPLEX | SLIT DIAPHRAGM | GLOMERULAR PROTEIN | ANGIOTENSIN-II | NEPHRIN EXPRESSION | ENDOPLASMIC-RETICULUM STRESS | NEPHROTIC SYNDROME | Phosphorylation | Ribosomal Protein S6 Kinases - metabolism | Diabetic Nephropathies - etiology | Diabetes Mellitus, Type 2 - genetics | Multiprotein Complexes | Podocytes - enzymology | Diabetic Nephropathies - drug therapy | Endoplasmic Reticulum - metabolism | Male | Mechanistic Target of Rapamycin Complex 1 | Mice, Mutant Strains | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Glomerular Basement Membrane - pathology | Regulatory-Associated Protein of mTOR | Cell Differentiation | Membrane Proteins - metabolism | Diabetic Nephropathies - prevention & control | Diabetes Mellitus, Type 2 - complications | Disease Models, Animal | Carrier Proteins - physiology | Proteins - physiology | Sirolimus - therapeutic use | Mice, Inbred C57BL | Podocytes - pathology | Mice, Knockout | Carrier Proteins - genetics | Tumor Suppressor Proteins - physiology | Adaptor Proteins, Signal Transducing | Glomerular Mesangium - pathology | Animals | Podocytes - drug effects | Podocytes - physiology | Mice | Protein Processing, Post-Translational | TOR Serine-Threonine Kinases | Enzyme Activation | Proteins - antagonists & inhibitors | Diabetic nephropathies
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2011, Volume 121, Issue 5, pp. 2013 - 2024
Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of end-stage renal failure. Identification of single-gene causes of SRNS has generated some... 
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | GENE | COENZYME-Q BIOSYNTHESIS | DIPHOSPHATE SYNTHASE SUBUNIT-2 | NPHS2 | GLOMERULAR PROTEIN | UBIQUINONE BIOSYNTHESIS | COQ DEFICIENCY | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | SACCHAROMYCES-CEREVISIAE | Deafness | Gene mutations | Genetic aspects | Nephrotic syndrome | Research | Health aspects | Risk factors
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3243 - 3253
Journal Article
Kidney International, ISSN 0085-2538, 01/2012, Volume 81, Issue 1, pp. 40 - 55
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 08/2017, Volume 28, Issue 8, pp. 2420 - 2430
In the live animal, tissue autofluorescence arises from a number of biologically important metabolites, such as the reduced form of nicotinamide adenine... 
LIPID DOMAINS | OXIDATIVE STRESS | STATES | NADH | LIVE TISSUE | BIOLOGY | 2ND-HARMONIC GENERATION | REPRESENTATION | UROLOGY & NEPHROLOGY | PHASOR APPROACH | MICROSCOPY | Kidney - metabolism | Animals | Kidney - diagnostic imaging | Mice, Inbred C57BL | Male | Kidney - cytology | Mice | Microscopy, Fluorescence, Multiphoton | Intravital Microscopy | endothelium | metabolism | tubules | podocyte | Basic Research
Journal Article