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Journal Article
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 07/2015, Volume 12, Issue 1, p. 136
Background: Inflammation and the excess production of reactive oxygen species (ROS) contribute significantly to the pathogenesis of ischemic retinopathies such... 
Retinal ischemia | Inflammation | Müller cell | NADPH oxidase | Ganglion cell | Microglia | DIABETIC-RETINOPATHY | NADPH OXIDASE 4 | ACTIVATION | ANGIOGENESIS | Muller cell | IMMUNOLOGY | NEUROSCIENCES | IN-VIVO | DISEASE | NEOVASCULARIZATION | MULLER CELLS | PREMATURITY | ENDOTHELIAL GROWTH-FACTOR | Pyrazoles - therapeutic use | Reactive Oxygen Species - metabolism | Neuroglia - pathology | Vascular Endothelial Growth Factor A - metabolism | Retinitis - prevention & control | Ischemia - prevention & control | Neuroglia - drug effects | NADPH Oxidases - drug effects | Chemokine CCL2 - metabolism | NADH, NADPH Oxidoreductases - drug effects | Ischemia - pathology | Disease Models, Animal | Pyrazoles - pharmacology | Pyridines - therapeutic use | Retinitis - pathology | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Rats | Hypoxia - complications | NADPH Oxidase 4 | Cell Adhesion - drug effects | NADPH Oxidase 1 | Intercellular Adhesion Molecule-1 - metabolism | Animals | Neuroglia - metabolism | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Pyridines - pharmacology | In Vitro Techniques | Ischemia - etiology | Retinitis - metabolism | Oxidases | Diabetic retinopathy | RNA | Analysis | Albumin | Gene expression | Vascular endothelial growth factor | Enzyme-linked immunosorbent assay | Protein binding
Journal Article
Clinical Science, ISSN 0143-5221, 12/2017, Volume 131, Issue 24, pp. 2865 - 2883
For many years, oxidative stress arising from the ubiquitous production of reactive oxygen species (ROS) has been implicated in the pathogenesis of various eye... 
DIABETIC-RETINOPATHY | MEDICINE, RESEARCH & EXPERIMENTAL | RETINAL GANGLION-CELLS | OPTIC-NERVE HEAD | NADPH OXIDASE | OPEN-ANGLE GLAUCOMA | PIGMENT EPITHELIAL-CELLS | RENIN-ANGIOTENSIN SYSTEM | INFLAMMATION IN-VITRO | ALPHA-LIPOIC ACID | HUMAN TRABECULAR MESHWORK
Journal Article
The Journal of Pathology, ISSN 0022-3417, 06/2016, Volume 239, Issue 2, pp. 152 - 161
Leakage of fluid from blood vessels, leading to oedema, is a key feature of many diseases including hyperoxic acute lung injury (HALI), which can occur when... 
VEGF‐D | pulmonary oedema | hyperoxia | VEGFR‐3 | VEGFR‐2 | vascular leak | hyperoxic acute lung injury | VEGFR-3 | VEGFR-2 | VEGF-D | LYMPHATIC ENDOTHELIUM | METASTASIS | MOUSE | TYROSINE KINASES | VASCULAR-PERMEABILITY | TUMOR ANGIOGENESIS | FACTOR RECEPTOR-3 | OXYGEN-TOXICITY | PATHOLOGY | CELL-DEATH | ONCOLOGY | ENDOTHELIAL GROWTH-FACTOR | Bronchoalveolar Lavage Fluid | Humans | Male | Pulmonary Edema - etiology | Oxygen - metabolism | Vascular Endothelial Growth Factor D - administration & dosage | Hyperoxia - complications | Hyperoxia - metabolism | Pulmonary Edema - complications | Female | Pulmonary Edema - pathology | Acute Lung Injury - metabolism | Lung - metabolism | Vascular Endothelial Growth Factor D - genetics | Pulmonary Edema - metabolism | Lung - pathology | Signal Transduction | Mice, Inbred C57BL | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Mice, SCID | Acute Lung Injury - pathology | Mice, Knockout | Hyperoxia - pathology | Xenograft Model Antitumor Assays | Vascular Endothelial Growth Factor D - metabolism | Animals | Cell Line, Tumor | Mice, Inbred NOD | Mice | Vascular Endothelial Growth Factor Receptor-3 - genetics | Acute Lung Injury - complications | Acute respiratory distress syndrome | Dropsy | Edema | Vascular endothelial growth factor | Original Papers | Original Paper
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 01/2010, Volume 518, Issue 1, pp. 41 - 63
Retinopathy of prematurity (ROP) is characterized by deficits in the scotopic pathway, although the cellular locus for these deficits is not clear. Here we... 
retina | amino acid | rod pathway | neovascularization | renin‐angiotensin system | ischemia | pattern recognition | Amino acid | Ischemia | Retina | Neovascularization | Pattern recognition | Renin-angiotensin system | Rod pathway | PROTEIN-KINASE-C | MONOCARBOXYLATE TRANSPORT INHIBITION | OXYGEN-INDUCED RETINOPATHY | CAT RETINA | CHRONIC PLACENTAL INSUFFICIENCY | ROD BIPOLAR CELLS | MAMMALIAN RETINA | NEUROSCIENCES | AMINO-ACID SIGNATURES | AII-AMACRINE | RETINAL GANGLION-CELLS | ZOOLOGY | renin-angiotensin system | Amacrine Cells - drug effects | Retina - drug effects | Glycine - metabolism | Tetrazoles - pharmacology | Valsartan | gamma-Aminobutyric Acid - metabolism | Amacrine Cells - pathology | Humans | Amacrine Cells - metabolism | Angiotensin II Type 1 Receptor Blockers - pharmacology | Angiotensin II Type 1 Receptor Blockers - metabolism | Neuroprotective Agents - metabolism | Tetrazoles - metabolism | Amino Acids - metabolism | Neuroprotective Agents - pharmacology | Retina - cytology | Color Vision - physiology | Infant, Newborn | Animals, Newborn | Valine - analogs & derivatives | Rats | Random Allocation | Rats, Sprague-Dawley | Retina - chemistry | Animals | Receptor, Angiotensin, Type 2 - metabolism | Valine - metabolism | Receptor, Angiotensin, Type 1 - metabolism | Retinopathy of Prematurity - metabolism | Valine - pharmacology | Retina - pathology | Retinopathy of Prematurity - pathology
Journal Article