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SCIENCE SIGNALING, ISSN 1945-0877, 07/2019, Volume 12, Issue 589, p. eaay4494
Selected members of the Wnt signaling community met during a 4-day period in October 2018 to discuss the current challenges and opportunities associated with... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Wnt protein
Journal Article
Bone, ISSN 8756-3282, 08/2018, Volume 113, pp. 105 - 113
CD82 is a widely expressed member of the tetraspanin family of transmembrane proteins known to control cell signaling, adhesion, and migration. Tetraspanin... 
Mouse model | Bone remodeling | Adipocytes | CD82 | Osteoblasts | Tetraspanin | FUSION | NICHE | MESENCHYMAL STEM-CELLS | OSTEOCLASTOGENESIS | INVASION | ENDOCRINOLOGY & METABOLISM | DIFFERENTIATION | PROTEINS | EXPRESSION | MEMBRANE MICRODOMAIN | HEMATOPOIETIC STEM | Bones | Growth | Density | Analysis | Cells | Membrane proteins
Journal Article
DEVELOPMENTAL DYNAMICS, ISSN 1058-8388, 10/2015, Volume 244, Issue 10, pp. 1347 - 1355
Canonical and noncanonical Wnt signaling pathways both play pivotal roles in bone development. Wntless/GPR177 is a chaperone protein that is required for... 
Col2a1 | CELLS | Osteocalcin | Wnt secretion | MESENCHYMAL PROGENITORS | ANATOMY & MORPHOLOGY | MOUSE | OSTEOGENESIS | DEVELOPMENTAL BIOLOGY | skeletal development | CHONDROCYTE DIFFERENTIATION | RECIPROCAL REGULATION | Dermo1 | PATHWAY | MATURE OSTEOBLASTS | WNT | EXPRESSION | Wntless | Embryonic development
Journal Article
by Lu, D and Li, JS and Liu, HD and Foxa, GE and Weaver, K and Li, J and Williams, BO and Yang, T
JOURNAL OF BONE AND MINERAL RESEARCH, ISSN 0884-0431, 10/2018, Volume 33, Issue 10, pp. 1773 - 1784
Single-nucleotide polymorphisms in the LRP1 gene coding sequence are associated with low bone mass, and cell culture studies suggest that LRP1 plays a role in... 
RANKL | LRP1 | LACTOFERRIN | MACROPHAGES | KAPPA-B | OSTEOPOROSIS | OSTEOCLASTOGENESIS | MICROPHTHALMIA TRANSCRIPTION FACTOR | NUCLEAR-FACTOR | ENDOCRINOLOGY & METABOLISM | SMOOTH-MUSCLE-CELLS | DIFFERENTIATION | RECEPTOR-RELATED PROTEIN-1 | MAPK PATHWAY | EXPRESSION | Genetic research | Bones | Density
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 10/2018, Volume 33, Issue 10, pp. 1773 - 1784
Journal Article
Bone, ISSN 8756-3282, 06/2013, Volume 54, Issue 2, p. 244
Bone has long been known to be responsive to mechanical loading. For at least 25years it has been known that osteocytes sense mechanical load, and because of... 
Osteoporosis
Journal Article
BONE RESEARCH, ISSN 2095-4700, 03/2018, Volume 6, Issue 1, pp. 7 - 12
Imbalances between bone formation and bone resorption, which can occur due to aging or sex hormone deprivation, result in decreased bone mass and an increased... 
FIBROSIS | CELLS | IN-VITRO | ACTIVATION | GALECTIN-3 | PROTEIN | GENE-EXPRESSION | BETA-CATENIN | MONOCLONAL-ANTIBODIES | OSTEOPOROSIS | CELL & TISSUE ENGINEERING | Aging
Journal Article
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, ISSN 0884-0431, 5/2017, Volume 32, Issue 5, pp. 883 - 888
The Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/CRISPR-associated protein (Cas) pathway is revolutionizing biological research. Modifications... 
Journal Article
Cancer Research, ISSN 0008-5472, 02/2013, Volume 73, Issue 3 Supplement, pp. C47 - C47
Journal Article
Cancer Research, ISSN 0008-5472, 10/2013, Volume 73, Issue 19 Supplement, pp. C49 - C49
Journal Article
Bone Reports, ISSN 2352-1872, 06/2019, Volume 10, p. 100196
We used a myeloid-specific Cre to conditionally delete CD82 in mouse osteoclasts and their precursors. In contrast to global loss of CD82 (gKO), conditional... 
Genetic mouse model | Cytoskeleton | Osteoclast | Adhesion | Tetraspanin
Journal Article
Developmental Dynamics, ISSN 1058-8388, 10/2015, Volume 244, Issue 10, pp. 1347 - 1355
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 09/2012, Volume 27, Issue 9, p. 1849
Journal Article
Bone, ISSN 8756-3282, 2013, Volume 54, Issue 2, pp. 244 - 249
Abstract Bone has long been known to be responsive to mechanical loading. For at least 25 years it has been known that osteocytes sense mechanical load, and... 
Orthopedics | Sclerostin | B-catenin | SOST | Wnt | Osteocyte | Lrp5 | SCLEROSTIN ANTIBODY | NEGATIVE REGULATOR | TRABECULAR BONE | HIGH-BONE-MASS | OSTEOPOROSIS-PSEUDOGLIOMA SYNDROME | IN-VIVO | ENDOCRINOLOGY & METABOLISM | RECEPTOR-RELATED PROTEIN-5 | PARATHYROID-HORMONE | FRIZZLED-RELATED PROTEIN-1 | VAN-BUCHEM-DISEASE | Bone and Bones - pathology |