X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (35) 35
humans (31) 31
nephrotoxicity (11) 11
animals (10) 10
cystinosis (10) 10
epithelial-cells (10) 10
male (10) 10
cells, cultured (9) 9
pharmacology & pharmacy (9) 9
biomedicine (8) 8
cystinosis - metabolism (8) 8
pediatrics (8) 8
cell line (7) 7
in-vitro (7) 7
kidney tubules, proximal - metabolism (7) 7
nephropathic cystinosis (7) 7
physiology (7) 7
protein (7) 7
urology & nephrology (7) 7
analysis (6) 6
cells (6) 6
cystinosis - pathology (6) 6
epithelial cells (6) 6
fanconi-syndrome (6) 6
female (6) 6
glutathione (6) 6
kidney tubules, proximal - cytology (6) 6
kidneys (6) 6
model (6) 6
p-glycoprotein (6) 6
adenosine triphosphate - metabolism (5) 5
biochemistry, general (5) 5
cell survival - drug effects (5) 5
cysteamine (5) 5
cystine - metabolism (5) 5
expression (5) 5
fibroblasts (5) 5
gene expression (5) 5
kidney (5) 5
kidney - pathology (5) 5
microfluidics (5) 5
toxicology (5) 5
uremic toxins (5) 5
article (4) 4
biochemistry & molecular biology (4) 4
cell biology (4) 4
child (4) 4
epithelial cells - metabolism (4) 4
hemodialysis (4) 4
increased apoptosis (4) 4
inhibition (4) 4
life sciences (4) 4
metabolism (4) 4
mice (4) 4
multidrug resistance-associated proteins - metabolism (4) 4
organic cation transporter (4) 4
pharmacology/toxicology (4) 4
physiological aspects (4) 4
proteins (4) 4
proximal tubular cells (4) 4
proximal tubule (4) 4
transport (4) 4
transporter (4) 4
adolescent (3) 3
adult (3) 3
amino acid transport systems, neutral - genetics (3) 3
anions (3) 3
atp (3) 3
biophysics (3) 3
biotechnology (3) 3
case-control studies (3) 3
cell line, transformed (3) 3
ciptec (3) 3
cystine (3) 3
cystinosis - genetics (3) 3
dose-response relationship, drug (3) 3
drug development (3) 3
efflux (3) 3
endocytosis (3) 3
endocytosis - physiology (3) 3
endothelial-cells (3) 3
epithelial cells - cytology (3) 3
exposure (3) 3
fanconi syndrome (3) 3
hek293 cells (3) 3
human physiology (3) 3
human-kidney (3) 3
infant (3) 3
kidney - metabolism (3) 3
kidney diseases (3) 3
living membrane (3) 3
lysosomes - metabolism (3) 3
medicine & public health (3) 3
membrane (3) 3
metabolites (3) 3
middle aged (3) 3
multidisciplinary sciences (3) 3
mutations (3) 3
neoplasm proteins - metabolism (3) 3
nephrology (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Drug Metabolism and Disposition, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, p. 592
Cisplatin is a cytostatic drug used for treatment of solid organ tumors. The main adverse effect is organic cation transporter 2 (OCT2)–mediated... 
Efflux | Organic cation transporter | Toxicity | Epithelial cells | Pyrimethamine | Cytotoxicity | Exposure | Oct-2 protein | Gene expression | Substrates | Cisplatin | Diclofenac | Sensitivity | Anions | Sodium | Extrusion | Viability | Transporter | Tumors
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 02/2016, Volume 13, p. 933
Apical transport is key in renal function, and the activity of efflux transporters and receptor-mediated endocytosis is pivotal in this process. The... 
Journal Article
Plos One, ISSN 1932-6203, 2013, Volume 8, Issue 8, p. e71199
BACKGROUND: Chronic kidney disease (CKD) is characterized by the progressive accumulation of various potential toxic solutes. Furthermore, uremic plasma is a... 
METABOLITES | TOXICOKINETICS | MAGNETIC-RESONANCE-SPECTROSCOPY | DIMETHYLSULFOXIDE | MULTIDISCIPLINARY SCIENCES | P-CRESOL | TOXINS | SERUM | HUMAN URINE | DIMETHYL SULFONE | H-1 | Uremia - diagnosis | Magnetic Resonance Spectroscopy | Toxins, Biological - blood | Humans | Middle Aged | Cells, Cultured | Metabolome | Male | Biomarkers - blood | Chromatography, High Pressure Liquid | Renal Insufficiency, Chronic - complications | Metabolomics - methods | Case-Control Studies | Renal Insufficiency, Chronic - pathology | Renal Insufficiency, Chronic - metabolism | Flow Cytometry | Kidney Tubules, Proximal | Uremia - blood | Adult | Female | Uremia - etiology | Renal Dialysis | Nitriles | Nuclear magnetic resonance spectroscopy | Diagnostic imaging | Precipitation (Meteorology) | Chronic kidney failure | Metabolites | Vimentin | Pediatrics | Hydroxyisobutyric acid | Nuclear magnetic resonance--NMR | Mesenchyme | Laboratories | Identification methods | Hemodialysis | Genomes | Solutes | Retention | Magnetic resonance spectroscopy | Proteins | Toxicology | Mitochondria | Sample preparation | Ultrafiltration | Physiology | Life sciences | Urine | Pharmacology | Patients | Deproteinization | Chromatography | Acetonitrile | Biomarkers | Scientific imaging | Dialysis | Toxins | Kidney diseases | NMR spectroscopy | Viability | Mass spectrometry | Clear cell-type renal cell carcinoma | Metabolic disorders | Kidney transplantation | Nuclear magnetic resonance | NMR
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2013, Volume 110, Issue 17, p. 7014
  Receptor-mediated endocytosis, involving megalin and cubilin, mediates renal proximal-tubular reabsorption and is decreased in Dent disease because of... 
Proteins | Endocytosis | T cell receptors | Mutation | Kidney diseases | Binding sites
Journal Article
Biochimica et Biophysica Acta (BBA) - General Subjects, ISSN 0304-4165, 09/2019, p. 129433
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 09/2018, Volume 46, Issue 9, pp. 1338 - 1350
Journal Article
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 2010, Volume 339, Issue 2, pp. 449 - 457
Journal Article
Pflügers Archiv : European Journal of Physiology, ISSN 0031-6768, 2013, Volume 465, Issue 12, pp. 1701 - 1714
Several organic cations, such as guanidino compounds and polyamines, have been found to accumulate in plasma of patients with kidney failure due to inadequate... 
OCT | Acrolein | Biomedicine | Human Physiology | Guanidine | Uremic toxin | Human proximal tubule cell | Polyamines | PHYSIOLOGY | NONRENAL DRUG CLEARANCE | PROTEIN-BINDING