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1. Full Text P2X3 Receptor Involvement in Pain States
by Wirkner, Kerstin and Sperlagh, Beata and Illes, Peter
Molecular Neurobiology, ISSN 0893-7648, 10/2007, Volume 36, Issue 2, pp. 165 - 183
The understanding of how pain is processed at each stage in the peripheral and central nervous system is the precondition to develop new therapies for the... 
Neurology | Medicine & Public Health | P2X 3 receptor | Neurophatic pain | Inflammation | Acute pain | Cell Biology | receptor | P2X | Receptors, Purinergic P2 - chemistry | Animals | Receptors, Purinergic P2X3 | Viscera - physiology | Adenosine Triphosphate - metabolism | Humans | Receptors, Purinergic P2 - metabolism | Migraine Disorders - physiopathology | Neurons - metabolism | Neoplasms - physiopathology | Pain - metabolism | Inflammation - physiopathology | Pain management
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2. Full Text Evaluating selection bias in a population-based cohort study with low baseline participation: the LIFE-Adult-Study
by Enzenbach, C and Wicklein, B and Wirkner, K and Loeffler, M
BMC MEDICAL RESEARCH METHODOLOGY, ISSN 1471-2288, 07/2019, Volume 19, Issue 1, pp. 135 - 14
BackgroundParticipation in epidemiologic studies is steadily declining, which may result in selection bias. It is therefore an ongoing challenge to clarify the... 
Participation | NONRESPONSE | RESPONDENTS | Selection bias | RISK | Reasons for nonparticipation | PREVALENCE | Validity | RATES | REPRESENTATIVENESS | Cohort study | HEALTH CARE SCIENCES & SERVICES | RECRUITMENT EFFORTS | HEALTH-STATUS
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3. Full Text Novel anthropometry based on 3D-bodyscans applied to a large population based cohort
by Löffler-Wirth, Henry and Willscher, Edith and Ahnert, Peter and Wirkner, Kerstin and Engel, Christoph and Loeffler, Markus and Binder, Hans
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0159887
Three-dimensional (3D) whole body scanners are increasingly used as precise measuring tools for the rapid quantification of anthropometric measures in... 
EXPRESSION LANDSCAPES | OBESITY | BODY SCANNER | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | WAIST | VALIDATION | RISK | PREVALENCE | PARTICIPANTS | ADIPOSE-TISSUE | Humans | Middle Aged | Imaging, Three-Dimensional - methods | Adult | Anthropometry - methods | Female | Male | Aged | Germany | Cohort Studies | Research | Epidemiology | Scanning devices | Analysis | Anthropometry | Cluster analysis | Scanners | Three dimensional bodies | Body mass index | Civilization | Maps | Population | Bioinformatics | Automation | Human body | Mortality | Data processing | Stability analysis | Interdisciplinary aspects | Metabolism | Hip | Studies | Self organizing maps | Body mass | Body size | Men | Health informatics | Cancer
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4. Full Text Parameters of pulse wave velocity: determinants and reference values assessed in the population-based study LIFE-Adult
by Baier, Daniel and Teren, Andrej and Wirkner, Kerstin and Loeffler, Markus and Scholz, Markus
Clinical Research in Cardiology, ISSN 1861-0684, 11/2018, Volume 107, Issue 11, pp. 1050 - 1061
Parameters of arterial stiffness such as pulse wave velocity (PWV) were recently proposed as independent risk factors of cardiovascular events. We analyse... 
Medicine & Public Health | Arterial stiffness | Brachial to ankle | Blood pressure | Cardiovascular risk stratification | Cardiology | Brachial to femoral | Carotid to femoral | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | COMPONENTS | RISK | SMOKING | AORTIC STIFFNESS | BLOOD-PRESSURE | PREDICTION | ALL-CAUSE | ASSOCIATION | Medicine, Experimental | Medical research | Epidemiology | Elderly people | Femur | Identification methods | Health risks | Population studies | Risk analysis | Parameter identification | Velocity | Blood | Subgroups | Risk factors | Ankle | Correlation analysis | Risk assessment | Determinants | Stiffness | Wave velocity | Cardiovascular diseases | Health risk assessment | Elderly | Age | Geriatrics | Original Paper
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5. Full Text P2X7 receptors in the nervous system
by Sperlágh, Beáta and Vizi, E. Sylvester and Wirkner, Kerstin and Illes, Peter
Progress in Neurobiology, ISSN 0301-0082, 04/2006, Volume 78, Issue 6, pp. 327 - 346
P2X receptors are ligand-gated ion channels, expressed as homo-oligomeric assemblies of individual subunits. They are widely distributed at immunocompetent... 
Neuron | receptor | P2X | Astrocyte | ATP | Microglia | Presynaptic | Central Nervous System - physiology | Receptors, Purinergic P2X7 | Peripheral Nervous System - physiology | Animals | Receptors, Purinergic P2 | Humans | Neuroglia - physiology | Neurons - physiology
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6. Full Text Association of serum 25-hydroxyvitamin D concentrations with sleep phenotypes in a German community sample
by Dogan-Sander, E and Willenberg, A and Batmaz, I and Enzenbach, C and Wirkner, K and Kohls, E and Mergl, R and Thiery, J and Kratzsch, J and Hegerl, U and Sander, C
PLOS ONE, ISSN 1932-6203, 07/2019, Volume 14, Issue 7, p. e0219318
Background Sleep disorders and vitamin D deficiency are among the most common health problems. Few studies investigated the effect of vitamin D on objectively... 
OBESITY | QUALITY | POLYSOMNOGRAPHY | MULTIDISCIPLINARY SCIENCES | ADULTS | DISORDERS | HEALTH | PREVALENCE | VITAMIN-D-METABOLISM | SOCIOECONOMIC-STATUS | DURATION | Physiological aspects | Calcifediol | Sleep | Alfacalcidol | Vitamin D | Health aspects | Analysis | Immunoassay | Daytime | Night | Laboratories | Health problems | Psychotherapy | Sleep apnea | Males | Sleep disorders | Civilization | Regression models | Pain | Quality | Sleepiness | Sleep and wakefulness | 25-Hydroxyvitamin D | Phenotypes | Nutrient deficiency | Parameters | Vitamin deficiency | Regression analysis | Electrochemiluminescence | Studies | Calciferol | Socioeconomic factors | Diabetes | Females | Psychiatry
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7. Full Text Recorded and reported sleepiness: The association between brain arousal in resting state and subjective daytime sleepiness
by Jawinski, Philippe and Kittel, Jennifer and Sander, Christian and Huang, Jue and Spada, Janek and Ulke, Christine and Wirkner, Kerstin and Hensch, Tilman and Hegerl, Ulrich
Sleep, ISSN 0161-8105, 07/2017, Volume 40, Issue 7
Objectives: Daytime sleepiness is a significant public health concern. Early evidence points toward the computerized VIGALL (Vigilance Algorithm Leipzig) as... 
Epworth Sleepiness Scale | Vigilance | EEG | Arousal | ECG | Daytime sleepiness | VIGALL | PERFORMANCE | daytime sleepiness | SLOW-WAVE | RISK | NEUROSCIENCES | CLINICAL NEUROLOGY | vigilance | LATENCY TEST | QUALITY INDEX | EEG-VIGILANCE | HEART-RATE | SCALE | WAKEFULNESS TEST | FALLING ASLEEP | arousal | Reproducibility of Results | Disorders of Excessive Somnolence - physiopathology | Humans | Middle Aged | Male | Electroencephalography | Brain - physiology | Rest - physiology | Arousal - physiology | Algorithms | Sleep Stages - physiology | Wakefulness - physiology | Adult | Female | Aged | Cohort Studies | Sleep deprivation
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8. Full Text Reference intervals of nine steroid hormones over the life-span analyzed by LC-MS/MS: Effect of age, gender, puberty, and oral contraceptives
by Bae, Yoon Ju and Zeidler, Robert and Baber, Ronny and Vogel, Mandy and Wirkner, Kerstin and Loeffler, Markus and Ceglarek, Uta and Kiess, Wieland and Körner, Antje and Thiery, Joachim and Kratzsch, Juergen
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 10/2019, Volume 193, p. 105409
New reference intervals need to be established for a new analytical method with improved sensitivity and specificity. We aimed to establish the new reference... 
Liquid chromatography-tandem mass spectrometry | GAMLSS | Tanner stage | Oral contraceptives | Steroid hormones | Mini-puberty | SYSTEM | TESTOSTERONE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | CHALLENGES | AXIS | Puberty | Senescence | Laboratories | Menopause | Endocrine diseases | Hormones | Hydrocortisone | Aldosterone | Estradiol | Testosterone | Body mass index | Birth control | Contraceptives | Contraceptives (oral) | Progesterone | Androstenedione | Age
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9. Full Text Targeted On‐line SPE‐LC‐MS/MS Assay for the Quantitation of 12 Apolipoproteins from Human Blood
by Dittrich, Julia and Adam, Melanie and Maas, Hilke and Hecht, Max and Reinicke, Madlen and Ruhaak, L. Renee and Cobbaert, Christa and Engel, Christoph and Wirkner, Kerstin and Löffler, Markus and Thiery, Joachim and Ceglarek, Uta
PROTEOMICS, ISSN 1615-9853, 02/2018, Volume 18, Issue 3-4, pp. 1700279 - n/a
Laborious sample pretreatment of biological samples represents the most limiting factor for the translation of targeted proteomics assays from research to... 
targeted proteomics | apolipoproteins | preanalytics | confounding variables | quantitative proteomics | PROTEOMICS EXPERIMENTS | HUMAN PLASMA | CHROMATOGRAPHY/TANDEM MASS-SPECTROMETRY | QUANTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CLINICAL PROTEOMICS | HUMAN SERUM | PEPTIDE | LIPOPROTEIN METABOLISM | DIGESTION | REVEALS | Humans | Middle Aged | Solid Phase Extraction - methods | Female | Male | Aged | Proteomics - methods | Apolipoproteins - blood | Chromatography, Liquid - methods | Online Systems | Tandem Mass Spectrometry - methods | High-Throughput Screening Assays - methods | Apolipoproteins | Analysis | Biological properties | Triglycerides | Coagulants | Quantitation | Metabolism | Assaying | Biological samples | Cholesterol | Trypsin | Proteomics | Lipid metabolism | Pretreatment | Sampling | Immunoassays
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10. Full Text Normative values of the Epworth Sleepiness Scale (ESS), derived from a large German sample
by Sander, Christian and Hegerl, Ulrich and Wirkner, Kerstin and Walter, Nadja and Kocalevent, Rüya-Daniela and Petrowski, Katja and Glaesmer, Heide and Hinz, Andreas
Sleep and Breathing, ISSN 1520-9512, 12/2016, Volume 20, Issue 4, pp. 1337 - 1345
Daytime sleepiness is associated with several medical problems. The aim of this paper is to provide normative values for one of the most often used... 
Neurology | Pediatrics | Pneumology/Respiratory System | Medicine & Public Health | Normative values | Population-based study | Internal Medicine | Otorhinolaryngology | Dentistry | Daytime sleepiness | Epidemiology | Prognostic factors | POPULATION | INSOMNIA | RISK-FACTORS | DETERMINANTS | ACCIDENTS | ADULTS | PREVALENCE | CLINICAL NEUROLOGY | QUALITY INDEX | RESPIRATORY SYSTEM | VALIDITY | EXCESSIVE DAYTIME SLEEPINESS | Reproducibility of Results | Psychometrics - statistics & numerical data | Humans | Middle Aged | Risk Factors | Male | Reference Values | Statistics as Topic | Disorders of Excessive Somnolence - epidemiology | Alcohol Drinking - epidemiology | Smoking - epidemiology | Disorders of Excessive Somnolence - diagnosis | Sex Factors | Aged, 80 and over | Tobacco Use Disorder - epidemiology | Adult | Female | Surveys and Questionnaires | Aged | Sleep Apnea, Obstructive - epidemiology | Sleep Apnea, Obstructive - diagnosis | Germany | Observer Variation | Fatigue | Medical tests | Sleep
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11. Full Text Olfactory function is associated with cognitive performance: results from the population-based LIFE-Adult-Study
by Yahiaoui-Doktor, M and Luck, T and Riedel-Heller, SG and Loeffler, M and Wirkner, K and Engel, C
ALZHEIMERS RESEARCH & THERAPY, ISSN 1758-9193, 05/2019, Volume 11, Issue 1, pp. 43 - 43
BackgroundStudies in older adults or those with cognitive impairment have shown associations between cognitive and olfactory performance, but there are few... 
DEMENTIA | ALZHEIMERS-DISEASE | General population | Cognition | SNIFFIN-STICKS | EDUCATION | Olfactory function | NEUROSCIENCES | CLINICAL NEUROLOGY | IMPAIRMENT | DYSFUNCTION | DEFICITS | Cross-sectional | NORMATIVE DATA | ODOR IDENTIFICATION | Cognition disorders | Diagnosis | Health aspects | Risk factors | Middle age | Disease | Cognitive ability | Otolaryngology | Identification | Mental depression | Studies | Brain research | Education | Older people | Population | Adults | Dementia | Adaptation
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12. Full Text Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness
by Li, Dian and Rauscher, Franziska G and Choi, Eun Young and Wang, Mengyu and Baniasadi, Neda and Wirkner, Kerstin and Kirsten, Toralf and Thiery, Joachim and Engel, Christoph and Loeffler, Markus and Elze, Tobias
Ophthalmology, ISSN 0161-6420, 09/2019
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13. Full Text Testosterone imbalance may link depression and increased body weight in premenopausal women
by Stanikova, Daniela and Zsido, Rachel G and Luck, Tobias and Pabst, Alexander and Enzenbach, Cornelia and Bae, Yoon Ju and Thiery, Joachim and Ceglarek, Uta and Engel, Christoph and Wirkner, Kerstin and Stanik, Juraj and Kratzsch, Juergen and Villringer, Arno and Riedel-Heller, Steffi G and Sacher, Julia
Translational Psychiatry, ISSN 2158-3188, 12/2019, Volume 9, Issue 1, pp. 160 - 12
Accumulating evidence supports a link between depression and being overweight in women. Given previously reported sex differences in fat accumulation and... 
Testosterone | Hormone replacement therapy | Mental depression | Health risk assessment | Mediation
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14. Full Text Relationship between determinants of arterial stiffness assessed by diastolic and suprasystolic pulse oscillometry: comparison of vicorder and vascular explorer
by Teren, Andrej and