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The AAPS Journal, ISSN 1550-7416, 09/2017, Volume 19, Issue 5, p. 1276
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1208/s12248-017-0097-1... 
Type 2 diabetes | Medical colleges | Prostaglandins | Analysis | G proteins | Cardiovascular diseases | Health aspects | Membrane proteins
Journal Article
Endocrinology, ISSN 0013-7227, 06/2017, Volume 158, Issue 6, p. 1645
Abstract The α -subunit of the heterotrimeric Gz protein, Gα z, promotes β -cell death and inhibits β -cell replication when pancreatic islets are challenged... 
Cell proliferation | Transcription | Streptozocin | Diabetes mellitus | Mortality | Inflammation | Insulin | Proteins | DNA nucleotidylexotransferase | Immune systems | Signaling | Hyperglycemia | Cell death | Rodents | Infiltration | Mice | Diabetes | Pancreas | Apoptosis
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 05/2016, Volume 30, Issue 5, pp. 543 - 556
A defining characteristic of type 1 diabetes mellitus (T1DM) pathophysiology is pancreatic [beta]-cell death and dysfunction, resulting in insufficient insulin... 
Journal Article
Journal of Physiology, ISSN 0022-3751, 02/2018, Volume 596, Issue 4, pp. 623 - 645
Obesity and diabetes are increasing problems around the world, and although even moderate weight loss can improve metabolic health, reduced calorie diets are... 
protein restriction | branched-chain amino acids | diabetes | obesity | DIETARY METHIONINE RESTRICTION | PHYSIOLOGY | WEIGHT-LOSS | LEUCINE RESTRICTION | NEUROSCIENCES | ENERGY-EXPENDITURE | INSULIN-RESISTANCE | HIGH-PROTEIN-DIET | HEPATIC STEATOSIS | GROWTH-FACTOR 21 | GLUCOSE-TOLERANCE | ADIPOSE-TISSUE | Blood Glucose - analysis | Caloric Restriction | Diet - adverse effects | Amino Acids, Branched-Chain - metabolism | Mice, Inbred C57BL | Diabetes Mellitus, Type 2 - prevention & control | Insulin Resistance | Male | Diabetes Mellitus, Type 2 - metabolism | Obesity - metabolism | Fibroblast Growth Factors - metabolism | Amino Acids, Branched-Chain - administration & dosage | Animals | Energy Metabolism | Weight Loss | Obesity - prevention & control | Diabetes Mellitus, Type 2 - etiology | Obesity - etiology | Mice | Insulin resistance | Fibroblast growth factors | Blood sugar | Branched chain amino acids | Reducing diets | Fibroblast growth factor | Adipose tissue | Body fat | Amino acids | Body weight loss | Leucine | Glucose | High fat diet | Proteins | Dietary restrictions | Protein composition | Rodents | Fibroblasts | Growth factors | Low protein diet | Sugar | Isoleucine | Obesity | Nutrient deficiency | Diabetes mellitus | Energy expenditure | Metabolism | Insulin | Feeding | Glucose tolerance | Energy balance | Weight control | Diet | Hypocaloric diet | Valine | Low fat diet | High protein diet | Metabolic disorders | Index Medicus | Research Paper | Endocrine, Nutrition and Metabolism | branched‐chain amino acids
Journal Article
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 12/2017, Volume 15, Issue 12, pp. 1792 - 1802
Cyclic AMP (cAMP) is an important second messenger that regulates a wide range of physiologic processes. In mammalian cutaneous melanocytes, cAMP-mediated... 
MIGRATION | MC1R | ONCOLOGY | CELLS IN-VITRO | SIGNALING PATHWAY | MELANOCORTIN 1 RECEPTOR | ULTRAVIOLET-RADIATION | HUMAN MELANOCYTES | EPAC | CAMP | ERK | CELL BIOLOGY | PTEN Phosphohydrolase - genetics | Guanine Nucleotide Exchange Factors - genetics | Mitogen-Activated Protein Kinase Kinases - genetics | Humans | Receptor, Melanocortin, Type 1 - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Colforsin - administration & dosage | Adenylyl Cyclases - drug effects | Melanoma - pathology | Telomere-Binding Proteins - genetics | Neoplasm Metastasis | Animals | Signal Transduction - drug effects | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Cyclic AMP - genetics | Mice | Adenylyl Cyclases - genetics | Cyclic AMP - metabolism | Cell proliferation | Protein kinase A | G protein-coupled receptors | Homeostasis | Melanocytes | Metastasis | Kinases | Metastases | Adenylate cyclase | Signal transduction | Receptors | Rodents | Inhibition | a-Melanocyte-stimulating hormone | Cell survival | AMP | MEK inhibitors | Melanoma | Cyclic AMP | Melanocortin | MAP kinase | Data processing | Pharmacology | siRNA | Rap1 protein | Signaling | Forskolin | Topical application | Mutation | PTEN protein | Cancer | Index Medicus | EPAC-RAP1 axis | melanoma progression | BRAF | Cyclic AMP signaling | PTEN melanoma
Journal Article
The AAPS Journal, ISSN 1550-7416, 9/2017, Volume 19, Issue 5, pp. 1276 - 1283
Cardiovascular disease is a common co-morbidity found with obesity-linked type 2 diabetes. Current pharmaceuticals for these two diseases treat each of them... 
Biochemistry, general | Biotechnology | cardiovascular disease | Biomedicine | type 2 diabetes | Pharmacy | GPCRs | prostaglandins | G proteins | Pharmacology/Toxicology | diabetes | Index Medicus
Journal Article
01/2013, ISBN 1303452960
Catastrophic cardiovascular events, such as myocardial infarction and ischemic stroke, are mediated by excessive platelet accumulation that results in arterial... 
Cellular biology | Pharmacology
Dissertation
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